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IKBKE downregulation increases chemosensitivity through pyroptosis mediated by the caspase-3/GSDME pathway in pancreatic cancer.

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Title: IKBKE downregulation increases chemosensitivity through pyroptosis mediated by the caspase-3/GSDME pathway in pancreatic cancer.
Authors: Ren T; Shandong Provincial Hospital Affiliated to Shandong First Medical University, 324 Jingwu Rd, Jinan, 250021, China.; Department of Oncology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 324 Jingwu Rd, Jinan, 250021, China., Chen X; Department of Oncology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 324 Jingwu Rd, Jinan, 250021, China., Wang X; Shandong University of Traditional Chinese Medicine, 4655 Daxue Rd, Jinan, 250355, China., Xu Y; Department of Liver Transplantation and Hepatobiliary Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 324 Jingwu Rd, Jinan, 250021, China., Shao N; Department of Oncology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 324 Jingwu Rd, Jinan, 250021, China. shaona@email.sdfmu.edu.cn.
Source: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2026 Feb 16; Vol. 45 (1). Date of Electronic Publication: 2026 Feb 16.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 8308647 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-9966 (Electronic) Linking ISSN: 03929078 NLM ISO Abbreviation: J Exp Clin Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: IKBKE downregulation increases chemosensitivity through pyroptosis mediated by the caspase-3/GSDME pathway in pancreatic cancer.
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  Data: <searchLink fieldCode="AU" term="%22Ren+T%22">Ren T</searchLink>; Shandong Provincial Hospital Affiliated to Shandong First Medical University, 324 Jingwu Rd, Jinan, 250021, China.; Department of Oncology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 324 Jingwu Rd, Jinan, 250021, China.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Department of Oncology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 324 Jingwu Rd, Jinan, 250021, China.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Shandong University of Traditional Chinese Medicine, 4655 Daxue Rd, Jinan, 250355, China.<br /><searchLink fieldCode="AU" term="%22Xu+Y%22">Xu Y</searchLink>; Department of Liver Transplantation and Hepatobiliary Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 324 Jingwu Rd, Jinan, 250021, China.<br /><searchLink fieldCode="AU" term="%22Shao+N%22">Shao N</searchLink>; Department of Oncology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 324 Jingwu Rd, Jinan, 250021, China. shaona@email.sdfmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%228308647%22">Journal of experimental & clinical cancer research : CR</searchLink> [J Exp Clin Cancer Res] 2026 Feb 16; Vol. 45 (1). <i>Date of Electronic Publication: </i>2026 Feb 16.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8308647 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1756-9966 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203929078%22">03929078 </searchLink><i>NLM ISO Abbreviation: </i>J Exp Clin Cancer Res <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1186/s13046-026-03670-1
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      – Code: eng
        Text: English
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      – TitleFull: IKBKE downregulation increases chemosensitivity through pyroptosis mediated by the caspase-3/GSDME pathway in pancreatic cancer.
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            NameFull: Ren T
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            NameFull: Chen X
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              Text: 2026 Feb 16
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              Y: 2026
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