The cyclin dependent kinase (CDK)7 inhibitor BS-181 inhibits pathogenic Cryptococcus species, causing G2/M arrest and a splicing defect.
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| Title: | The cyclin dependent kinase (CDK)7 inhibitor BS-181 inhibits pathogenic Cryptococcus species, causing G |
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| Authors: | Sethiya P; Centre for Infectious Diseases and Microbiology, Westmead Institute for Medical Research, Westmead, NSW , Australia.; Sydney Institute for Infectious Diseases, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW , Australia., Desmarini D; Centre for Infectious Diseases and Microbiology, Westmead Institute for Medical Research, Westmead, NSW , Australia.; Sydney Institute for Infectious Diseases, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW , Australia., Bowring B; Centre for Infectious Diseases and Microbiology, Westmead Institute for Medical Research, Westmead, NSW , Australia.; Sydney Institute for Infectious Diseases, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW , Australia., Dinh H; ARC Centre of Excellence in Synthetic Biology, School of Natural Sciences, Macquarie University, North Ryde, NSW, Australia., Cain AK; ARC Centre of Excellence in Synthetic Biology, School of Natural Sciences, Macquarie University, North Ryde, NSW, Australia., Parsania C; Cancer & Gene Regulation Laboratory Centenary Institute, The University of Sydney, Camperdown, NSW, Australia.; Centre for Rare Diseases & Gene Therapy Centenary Institute, The University of Sydney, Camperdown, NSW, Australia.; School of Medical Sciences, Faculty of Medicine & Health, The University of Sydney, Camperdown, NSW, Australia., Halliday CL; Sydney Institute for Infectious Diseases, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW , Australia.; Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, New South Wales Health Pathology, Westmead Hospital, Westmead, NSW., Chen SC; Sydney Institute for Infectious Diseases, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW , Australia.; Centre for Infectious Diseases and Microbiology Laboratory Services, Institute for Clinical Pathology and Medical Research, New South Wales Health Pathology, Westmead Hospital, Westmead, NSW.; Department of Infectious Diseases, Westmead Hospital, Westmead, NSW, Australia., Hewitt K; Westmead Bioresources Facility and Scientific Platforms, Westmead Institute for Medical Research, Westmead, NSW, Australia., Djordjevic JT; Centre for Infectious Diseases and Microbiology, Westmead Institute for Medical Research, Westmead, NSW , Australia.; Sydney Institute for Infectious Diseases, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW , Australia.; Department of Infectious Diseases, Westmead Hospital, Westmead, NSW, Australia. |
| Source: | Virulence [Virulence] 2026 Dec; Vol. 17 (1), pp. 2629100. Date of Electronic Publication: 2026 Feb 17. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-5608 (Electronic) Linking ISSN: 21505594 NLM ISO Abbreviation: Virulence Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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