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Taurine protects against gentamicin-induced neurotoxicity through dual modulation of Nrf2 and NF-κB pathways.

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Title: Taurine protects against gentamicin-induced neurotoxicity through dual modulation of Nrf2 and NF-κB pathways.
Authors: Farage AE; Department of Anatomy and Embryology, Faculty of Medicine, Kafrelsheikh University, Kafr Elsheikh 33511, Egypt. Electronic address: amira.farag2015@med.kfs.edu.eg., Taha M; Department of Anatomy, Al, Qunfudah Medical College, Umm Al-Qura University, Al-Qunfudhah, Saudi Arabia; Department of Anatomy and Embryology, Faculty of Medicine, Mansoura University, Egypt. Electronic address: mftaha@uqu.edu.sa., Khattab BA; Department of Anatomy and Embryology, Faculty of Medicine, Mansoura University, Egypt. Electronic address: Dr_basmakhattab99@mans.edu.eg., Al-Hazmi NE; Department of Chemistry, Division of Biology (Microbiology), University College of Qunfudah, Umm Al-Qura University, Saudi Arabia. Electronic address: nehazmi@uqu.edu.sa., Mohamed AEA; Department of Pharmacology, Faculty of Medicine, Al-Azhar University, Damietta, Egypt. Electronic address: Alaa.eisa.pharma@domazhermedicine.edu.eg., Mona MM; Associate professor of medical Biochemistry and Molecular Biology faculty of medicine Kafrelsheikh university, Egypt. Electronic address: marwa_mana@med.kfs.edu.eg., Abd-Elsalam MM; Histology & Cell Biology Department, Faculty of Medicine, Kafr Elsheikh University, Egypt. Electronic address: marwa_abdelbaky2014@med.kfs.edu.eg., Elsukary AE; Lecturer of forensic medicine and clinical toxicology, Faculty of medicine, Mansoura university, Egypt. Electronic address: ahmed.elsukary@mans.edu.eg., Sarhan MAFE; Biochemistry department, faculty of medicine, Mansoura university, Egypt; Institute of Pathology, Julius-Maximilians-University of Würzburg, Würzburg, Germany. Electronic address: mohamed.sarhan@uni-wuerzburg.de., Abdelmonsef AS; Department of Anatomy and Physiology, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia. Electronic address: Aabdalmaksoud@imamu.edu.sa., Baokbah TAS; Department of Medical Emergency Services, College of Health Sciences-AlQunfudah, Umm Al-Qura University, Saudi Arabia. Electronic address: tabaokbah@uqu.edu.sa., El-Shenbaby I; Clinical Pharmacology Department, Faculty of Medicine, Mansoura University, Egypt. Electronic address: shenbaby@mans.edu.eg., Eldesoky RT; Anatomic Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt. Electronic address: dr_rehabtalaat@mans.edu.eg., Hussin E; Department of Anatomy and Embryology, Faculty of Medicine, Mansoura University, Egypt. Electronic address: emaadeldeenhamed@mans.edu.eg.
Source: Tissue & cell [Tissue Cell] 2026 Jun; Vol. 100, pp. 103382. Date of Electronic Publication: 2026 Feb 09.
Publication Type: Journal Article
Journal Info: Publisher: Churchill Livingstone Country of Publication: Scotland NLM ID: 0214745 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3072 (Electronic) Linking ISSN: 00408166 NLM ISO Abbreviation: Tissue Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Taurine protects against gentamicin-induced neurotoxicity through dual modulation of Nrf2 and NF-κB pathways.
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  Data: <searchLink fieldCode="AU" term="%22Farage+AE%22">Farage AE</searchLink>; Department of Anatomy and Embryology, Faculty of Medicine, Kafrelsheikh University, Kafr Elsheikh 33511, Egypt. Electronic address: amira.farag2015@med.kfs.edu.eg.<br /><searchLink fieldCode="AU" term="%22Taha+M%22">Taha M</searchLink>; Department of Anatomy, Al, Qunfudah Medical College, Umm Al-Qura University, Al-Qunfudhah, Saudi Arabia; Department of Anatomy and Embryology, Faculty of Medicine, Mansoura University, Egypt. Electronic address: mftaha@uqu.edu.sa.<br /><searchLink fieldCode="AU" term="%22Khattab+BA%22">Khattab BA</searchLink>; Department of Anatomy and Embryology, Faculty of Medicine, Mansoura University, Egypt. Electronic address: Dr_basmakhattab99@mans.edu.eg.<br /><searchLink fieldCode="AU" term="%22Al-Hazmi+NE%22">Al-Hazmi NE</searchLink>; Department of Chemistry, Division of Biology (Microbiology), University College of Qunfudah, Umm Al-Qura University, Saudi Arabia. Electronic address: nehazmi@uqu.edu.sa.<br /><searchLink fieldCode="AU" term="%22Mohamed+AEA%22">Mohamed AEA</searchLink>; Department of Pharmacology, Faculty of Medicine, Al-Azhar University, Damietta, Egypt. Electronic address: Alaa.eisa.pharma@domazhermedicine.edu.eg.<br /><searchLink fieldCode="AU" term="%22Mona+MM%22">Mona MM</searchLink>; Associate professor of medical Biochemistry and Molecular Biology faculty of medicine Kafrelsheikh university, Egypt. Electronic address: marwa_mana@med.kfs.edu.eg.<br /><searchLink fieldCode="AU" term="%22Abd-Elsalam+MM%22">Abd-Elsalam MM</searchLink>; Histology & Cell Biology Department, Faculty of Medicine, Kafr Elsheikh University, Egypt. Electronic address: marwa_abdelbaky2014@med.kfs.edu.eg.<br /><searchLink fieldCode="AU" term="%22Elsukary+AE%22">Elsukary AE</searchLink>; Lecturer of forensic medicine and clinical toxicology, Faculty of medicine, Mansoura university, Egypt. Electronic address: ahmed.elsukary@mans.edu.eg.<br /><searchLink fieldCode="AU" term="%22Sarhan+MAFE%22">Sarhan MAFE</searchLink>; Biochemistry department, faculty of medicine, Mansoura university, Egypt; Institute of Pathology, Julius-Maximilians-University of Würzburg, Würzburg, Germany. Electronic address: mohamed.sarhan@uni-wuerzburg.de.<br /><searchLink fieldCode="AU" term="%22Abdelmonsef+AS%22">Abdelmonsef AS</searchLink>; Department of Anatomy and Physiology, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia. Electronic address: Aabdalmaksoud@imamu.edu.sa.<br /><searchLink fieldCode="AU" term="%22Baokbah+TAS%22">Baokbah TAS</searchLink>; Department of Medical Emergency Services, College of Health Sciences-AlQunfudah, Umm Al-Qura University, Saudi Arabia. Electronic address: tabaokbah@uqu.edu.sa.<br /><searchLink fieldCode="AU" term="%22El-Shenbaby+I%22">El-Shenbaby I</searchLink>; Clinical Pharmacology Department, Faculty of Medicine, Mansoura University, Egypt. Electronic address: shenbaby@mans.edu.eg.<br /><searchLink fieldCode="AU" term="%22Eldesoky+RT%22">Eldesoky RT</searchLink>; Anatomic Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt. Electronic address: dr_rehabtalaat@mans.edu.eg.<br /><searchLink fieldCode="AU" term="%22Hussin+E%22">Hussin E</searchLink>; Department of Anatomy and Embryology, Faculty of Medicine, Mansoura University, Egypt. Electronic address: emaadeldeenhamed@mans.edu.eg.
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  Data: <searchLink fieldCode="JN" term="%220214745%22">Tissue & cell</searchLink> [Tissue Cell] 2026 Jun; Vol. 100, pp. 103382. <i>Date of Electronic Publication: </i>2026 Feb 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Churchill+Livingstone%22">Churchill Livingstone </searchLink><i>Country of Publication: </i>Scotland <i>NLM ID: </i>0214745 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-3072 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200408166%22">00408166 </searchLink><i>NLM ISO Abbreviation: </i>Tissue Cell <i>Subsets: </i>MEDLINE
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        Text: English
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              Text: 2026 Jun
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