Adequacy criteria and reporting for prognostic and predictive profiling of biopsies from gastrointestinal neoplasia: A position paper from the Italian group of gastrointestinal pathologists, section of Italian society of anatomic pathology and cytology (GIPAD-SIAPeC-IAP).

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Title: Adequacy criteria and reporting for prognostic and predictive profiling of biopsies from gastrointestinal neoplasia: A position paper from the Italian group of gastrointestinal pathologists, section of Italian society of anatomic pathology and cytology (GIPAD-SIAPeC-IAP).
Authors: Parente P; Pathology Unit, Azienda Ospedaliero Universitaria Policlinico Foggia, Foggia, Italy., Grillo F; Pathology Unit, Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy; IRCCS Azienda Ospedaliera Metropolitana (AOM), Genoa, Italy. Electronic address: federica.grillo@unige.it., Callegarin M; Department of Medicine (DIMED), University of Padua, Padua, Italy., Luchini C; Department of Diagnostics and Public Health, Section of Pathology, University of Verona, Verona, Italy., Milione M; First Pathology Unit, Department of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Mattiolo P; Department of Diagnostics and Public Health, Section of Pathology, University of Verona, Verona, Italy., Gafà R; Anatomic Pathology Unit, Department of Translational Medicine, University of Ferrara, Ferrara, Italy; Azienda Ospedaliero-Universitaria S. Anna, Ferrara, Italy., Pagni F; Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; Department of Pathology, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy., Malapelle U; Department of Public Health, University Federico II of Naples, Naples, Italy., Macciomei MC; UOC Anatomia Patologica Azienda Ospedaliera San Camillo Forlanini, Roma, Italy., Giordano C; Dipartimento Di Scienze Radiologiche, Oncologiche ed Anatomo-Patologiche Sapienza, Università di Roma, roma, Italy; DAI Medicina Diagnostica e Radiologia, Policlinico Umberto I, 00161 Roma, Italy., D'Armiento M; Dipartimento di Sanità Pubblica, sezione di Anatomia Patologica Scuola di Medicina e Chirurgia, Università degli Studi di Napoli Federico II, Napoli, Italy., Ambrosio MR; Azienda Ospedaliera Universitaria 'SS. Annunziata', University of Calabria (UNICAL), Cosenza, Italy; UOC Anatomia Patologica, Azienda Toscana Nord Ovest, Pisa, Italy., Vasuri F; Pathology Unit, Santa Maria delle Croci Hospital, Ravenna, Italy; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy., Fanni D; Unit of Pathology, Azienda Ospedaliero Universitaria Cagliari, Cagliari, Italy; Department of Medical Sciences and Public Health University of Cagliari, Cagliari, Italy., Ingravallo G; Pathological Anatomy Unit, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy., Carbone FG; Surgical Pathology Unit, Santa Chiara Hospital, Azienda Sanitaria Universitaria Integrata, Trento, Italy., Pilozzi E; Department of Clinical and Molecular Medicine, 'Sapienza' University of Rome, Rome, Italy; UOC Anatomia Patologica Morfologia e Molecolare Azienda Ospedaliera-Universitaria Sant'Andrea, Roma, Italy., Falco E; Pathology Unit, Department of Medical Sciences University of Turin, Turin, Italy., Perrone G; Research Unit of Anatomical Pathology, Department of Medicine and Surgery, Università Campus Bio-Medico, Rome, Italy; Anatomical Pathology Operative Research Unit, Fondazione Policlinico Università Campus Bio-Medico, Rome, Italy., Caputo A; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Baronissi, Italy; Department of Pathology, University Hospital of Salerno, Salerno, Italy., Panarese I; UOC di Anatomia Patologica, Azienda Ospedaliero Universitarua 'Luigi Vanvitelli', Napoli, Italy., Pruneri G; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Cassoni P; Pathology Unit, Department of Medical Sciences University of Turin, Turin, Italy., Gambella A; Pathology Unit, Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy; IRCCS Azienda Ospedaliera Metropolitana (AOM), Genoa, Italy., Savino L; Unit of Anatomic Pathology, SS Annunziata Hospital, Chieti, Italy., Angerilli V; Surgical Pathology Unit, ULSS2 Marca Trevigiana, Treviso, Italy., Vanoli A; SC Anatomia Patologica, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; Anatomic Pathology Unit, Department of Molecular Medicine, University of Pavia, Pavia, Italy., Mastracci L; Pathology Unit, Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy; IRCCS Azienda Ospedaliera Metropolitana (AOM), Genoa, Italy., Fassan M; Department of Medicine (DIMED), University of Padua, Padua, Italy; Veneto Institute of Oncology, IOV-IRCCS, Padua, Italy.
Source: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver [Dig Liver Dis] 2026 Apr; Vol. 58 (4), pp. 444-455. Date of Electronic Publication: 2026 Feb 16.
Publication Type: Consensus Statement; Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 100958385 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3562 (Electronic) Linking ISSN: 15908658 NLM ISO Abbreviation: Dig Liver Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Adequacy criteria and reporting for prognostic and predictive profiling of biopsies from gastrointestinal neoplasia: A position paper from the Italian group of gastrointestinal pathologists, section of Italian society of anatomic pathology and cytology (GIPAD-SIAPeC-IAP).
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  Data: <searchLink fieldCode="AU" term="%22Parente+P%22">Parente P</searchLink>; Pathology Unit, Azienda Ospedaliero Universitaria Policlinico Foggia, Foggia, Italy.<br /><searchLink fieldCode="AU" term="%22Grillo+F%22">Grillo F</searchLink>; Pathology Unit, Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy; IRCCS Azienda Ospedaliera Metropolitana (AOM), Genoa, Italy. Electronic address: federica.grillo@unige.it.<br /><searchLink fieldCode="AU" term="%22Callegarin+M%22">Callegarin M</searchLink>; Department of Medicine (DIMED), University of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Luchini+C%22">Luchini C</searchLink>; Department of Diagnostics and Public Health, Section of Pathology, University of Verona, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Milione+M%22">Milione M</searchLink>; First Pathology Unit, Department of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mattiolo+P%22">Mattiolo P</searchLink>; Department of Diagnostics and Public Health, Section of Pathology, University of Verona, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Gafà+R%22">Gafà R</searchLink>; Anatomic Pathology Unit, Department of Translational Medicine, University of Ferrara, Ferrara, Italy; Azienda Ospedaliero-Universitaria S. Anna, Ferrara, Italy.<br /><searchLink fieldCode="AU" term="%22Pagni+F%22">Pagni F</searchLink>; Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; Department of Pathology, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.<br /><searchLink fieldCode="AU" term="%22Malapelle+U%22">Malapelle U</searchLink>; Department of Public Health, University Federico II of Naples, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Macciomei+MC%22">Macciomei MC</searchLink>; UOC Anatomia Patologica Azienda Ospedaliera San Camillo Forlanini, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Giordano+C%22">Giordano C</searchLink>; Dipartimento Di Scienze Radiologiche, Oncologiche ed Anatomo-Patologiche Sapienza, Università di Roma, roma, Italy; DAI Medicina Diagnostica e Radiologia, Policlinico Umberto I, 00161 Roma, Italy.<br /><searchLink fieldCode="AU" term="%22D'Armiento+M%22">D'Armiento M</searchLink>; Dipartimento di Sanità Pubblica, sezione di Anatomia Patologica Scuola di Medicina e Chirurgia, Università degli Studi di Napoli Federico II, Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Ambrosio+MR%22">Ambrosio MR</searchLink>; Azienda Ospedaliera Universitaria 'SS. Annunziata', University of Calabria (UNICAL), Cosenza, Italy; UOC Anatomia Patologica, Azienda Toscana Nord Ovest, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Vasuri+F%22">Vasuri F</searchLink>; Pathology Unit, Santa Maria delle Croci Hospital, Ravenna, Italy; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Fanni+D%22">Fanni D</searchLink>; Unit of Pathology, Azienda Ospedaliero Universitaria Cagliari, Cagliari, Italy; Department of Medical Sciences and Public Health University of Cagliari, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Ingravallo+G%22">Ingravallo G</searchLink>; Pathological Anatomy Unit, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Carbone+FG%22">Carbone FG</searchLink>; Surgical Pathology Unit, Santa Chiara Hospital, Azienda Sanitaria Universitaria Integrata, Trento, Italy.<br /><searchLink fieldCode="AU" term="%22Pilozzi+E%22">Pilozzi E</searchLink>; Department of Clinical and Molecular Medicine, 'Sapienza' University of Rome, Rome, Italy; UOC Anatomia Patologica Morfologia e Molecolare Azienda Ospedaliera-Universitaria Sant'Andrea, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Falco+E%22">Falco E</searchLink>; Pathology Unit, Department of Medical Sciences University of Turin, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Perrone+G%22">Perrone G</searchLink>; Research Unit of Anatomical Pathology, Department of Medicine and Surgery, Università Campus Bio-Medico, Rome, Italy; Anatomical Pathology Operative Research Unit, Fondazione Policlinico Università Campus Bio-Medico, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Caputo+A%22">Caputo A</searchLink>; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Baronissi, Italy; Department of Pathology, University Hospital of Salerno, Salerno, Italy.<br /><searchLink fieldCode="AU" term="%22Panarese+I%22">Panarese I</searchLink>; UOC di Anatomia Patologica, Azienda Ospedaliero Universitarua 'Luigi Vanvitelli', Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Pruneri+G%22">Pruneri G</searchLink>; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy; Department of Advanced Diagnostics, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cassoni+P%22">Cassoni P</searchLink>; Pathology Unit, Department of Medical Sciences University of Turin, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Gambella+A%22">Gambella A</searchLink>; Pathology Unit, Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy; IRCCS Azienda Ospedaliera Metropolitana (AOM), Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Savino+L%22">Savino L</searchLink>; Unit of Anatomic Pathology, SS Annunziata Hospital, Chieti, Italy.<br /><searchLink fieldCode="AU" term="%22Angerilli+V%22">Angerilli V</searchLink>; Surgical Pathology Unit, ULSS2 Marca Trevigiana, Treviso, Italy.<br /><searchLink fieldCode="AU" term="%22Vanoli+A%22">Vanoli A</searchLink>; SC Anatomia Patologica, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; Anatomic Pathology Unit, Department of Molecular Medicine, University of Pavia, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Mastracci+L%22">Mastracci L</searchLink>; Pathology Unit, Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy; IRCCS Azienda Ospedaliera Metropolitana (AOM), Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Fassan+M%22">Fassan M</searchLink>; Department of Medicine (DIMED), University of Padua, Padua, Italy; Veneto Institute of Oncology, IOV-IRCCS, Padua, Italy.
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