Nanobody-based IgG simultaneously inhibit the allergenic and enzymatic activity of the dominant honeybee venom allergen.

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Bibliographic Details
Title: Nanobody-based IgG simultaneously inhibit the allergenic and enzymatic activity of the dominant honeybee venom allergen.
Authors: Aagaard JB; Department of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark., Gandini R; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark., Ballegaard AR; Department of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark., Jensen BK; Department of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark., Dorn B; Department of Dermatology and Allergology, Justus Liebig University Giessen, Giessen, Germany., Larsen AVB; Department of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark., Lenstrup A; Department of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark., Sønderholm M; Department of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark., Miehe M; Department of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark., Pfützner W; Department of Dermatology and Allergology, Clinical & Experimental Allergology, Philipps University Marburg, Marburg, Germany., Jakob T; Department of Dermatology and Allergology, Justus Liebig University Giessen, Giessen, Germany. thilo.jakob@derma.med.uni-giessen.de., Andersen GR; Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark. gra@mbg.au.dk., Möbs C; Department of Dermatology and Allergology, Clinical & Experimental Allergology, Philipps University Marburg, Marburg, Germany. moebs@med.uni-marburg.de., Spillner E; Department of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark. e.spillner@bce.au.dk.
Source: Nature communications [Nat Commun] 2026 Feb 17; Vol. 17 (1), pp. 1814. Date of Electronic Publication: 2026 Feb 17.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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