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MyCARdiac score: integrating cardiac imaging and biomarkers to predict outcomes in RRMM patients receiving cilta-cel.

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Title: MyCARdiac score: integrating cardiac imaging and biomarkers to predict outcomes in RRMM patients receiving cilta-cel.
Authors: Wiemers TC; Department of Visceral, Transplantation, Vascular and Thoracic Surgery, University Hospital Leipzig, Leipzig, Germany. thomas.wiemers@medizin.uni-leipzig.de.; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany. thomas.wiemers@medizin.uni-leipzig.de.; Innovation Center Computer Assisted Surgery (ICCAS), University Hospital Leipzig, Leipzig, Germany. thomas.wiemers@medizin.uni-leipzig.de., Grieb N; Innovation Center Computer Assisted Surgery (ICCAS), University Hospital Leipzig, Leipzig, Germany., Ferle M; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany.; Innovation Center Computer Assisted Surgery (ICCAS), University Hospital Leipzig, Leipzig, Germany.; Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany.; Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI), University of Leipzig, Leipzig, Germany., Rade M; Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany., Fandrei D; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany.; Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany., Born P; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany., Fischer L; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany., Wang SY; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany., Seiffert S; Institute of Clinical Immunology, Medical Faculty, University of Leipzig, Leipzig, Germany., Grahnert A; Institute of Clinical Immunology, Medical Faculty, University of Leipzig, Leipzig, Germany., Friedrich M; Institute of Clinical Immunology, Medical Faculty, University of Leipzig, Leipzig, Germany., Baber R; Institute for Laboratory Medicine Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany.; Leipzig Medical Biobank, Medical Faculty, University of Leipzig, Leipzig, Germany., Kreuz M; Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany., Metzeler KH; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany., Herling M; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany., Herling CD; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany., Jentzsch M; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany., Franke GN; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany., Boldt A; Institute of Clinical Immunology, Medical Faculty, University of Leipzig, Leipzig, Germany., Neumuth T; Innovation Center Computer Assisted Surgery (ICCAS), University Hospital Leipzig, Leipzig, Germany., Köhl U; Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany.; Institute of Clinical Immunology, Medical Faculty, University of Leipzig, Leipzig, Germany., Reiche K; Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany.; Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI), University of Leipzig, Leipzig, Germany.; Institute of Clinical Immunology, Medical Faculty, University of Leipzig, Leipzig, Germany., Stegmann T; Department of Cardiology, University Hospital Leipzig, Leipzig, Germany., Denecke T; Department of Diagnostic and Interventional Radiology, University Hospital Leipzig, Leipzig, Germany., Platzbecker U; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany., Vučinić V; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany.; Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany., Meyer HJ; Department of Diagnostic and Interventional Radiology, University Hospital Leipzig, Leipzig, Germany., Lavall D; Department of Cardiology, University Hospital Leipzig, Leipzig, Germany., Merz M; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany.; Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany.; Myeloma and Cellular Therapy Services, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Source: Leukemia [Leukemia] 2026 Apr; Vol. 40 (4), pp. 832-836. Date of Electronic Publication: 2026 Feb 17.
Publication Type: Letter
Journal Info: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: MyCARdiac score: integrating cardiac imaging and biomarkers to predict outcomes in RRMM patients receiving cilta-cel.
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  Data: <searchLink fieldCode="AU" term="%22Wiemers+TC%22">Wiemers TC</searchLink>; Department of Visceral, Transplantation, Vascular and Thoracic Surgery, University Hospital Leipzig, Leipzig, Germany. thomas.wiemers@medizin.uni-leipzig.de.; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany. thomas.wiemers@medizin.uni-leipzig.de.; Innovation Center Computer Assisted Surgery (ICCAS), University Hospital Leipzig, Leipzig, Germany. thomas.wiemers@medizin.uni-leipzig.de.<br /><searchLink fieldCode="AU" term="%22Grieb+N%22">Grieb N</searchLink>; Innovation Center Computer Assisted Surgery (ICCAS), University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Ferle+M%22">Ferle M</searchLink>; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany.; Innovation Center Computer Assisted Surgery (ICCAS), University Hospital Leipzig, Leipzig, Germany.; Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany.; Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI), University of Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Rade+M%22">Rade M</searchLink>; Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Fandrei+D%22">Fandrei D</searchLink>; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany.; Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Born+P%22">Born P</searchLink>; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Fischer+L%22">Fischer L</searchLink>; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Wang+SY%22">Wang SY</searchLink>; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Seiffert+S%22">Seiffert S</searchLink>; Institute of Clinical Immunology, Medical Faculty, University of Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Grahnert+A%22">Grahnert A</searchLink>; Institute of Clinical Immunology, Medical Faculty, University of Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Friedrich+M%22">Friedrich M</searchLink>; Institute of Clinical Immunology, Medical Faculty, University of Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Baber+R%22">Baber R</searchLink>; Institute for Laboratory Medicine Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany.; Leipzig Medical Biobank, Medical Faculty, University of Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Kreuz+M%22">Kreuz M</searchLink>; Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Metzeler+KH%22">Metzeler KH</searchLink>; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Herling+M%22">Herling M</searchLink>; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Herling+CD%22">Herling CD</searchLink>; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Jentzsch+M%22">Jentzsch M</searchLink>; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Franke+GN%22">Franke GN</searchLink>; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Boldt+A%22">Boldt A</searchLink>; Institute of Clinical Immunology, Medical Faculty, University of Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Neumuth+T%22">Neumuth T</searchLink>; Innovation Center Computer Assisted Surgery (ICCAS), University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Köhl+U%22">Köhl U</searchLink>; Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany.; Institute of Clinical Immunology, Medical Faculty, University of Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Reiche+K%22">Reiche K</searchLink>; Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany.; Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI), University of Leipzig, Leipzig, Germany.; Institute of Clinical Immunology, Medical Faculty, University of Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Stegmann+T%22">Stegmann T</searchLink>; Department of Cardiology, University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Denecke+T%22">Denecke T</searchLink>; Department of Diagnostic and Interventional Radiology, University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Platzbecker+U%22">Platzbecker U</searchLink>; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Vučinić+V%22">Vučinić V</searchLink>; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany.; Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Meyer+HJ%22">Meyer HJ</searchLink>; Department of Diagnostic and Interventional Radiology, University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Lavall+D%22">Lavall D</searchLink>; Department of Cardiology, University Hospital Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Merz+M%22">Merz M</searchLink>; Department of Hematology, Hemostaseology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany.; Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany.; Myeloma and Cellular Therapy Services, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
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              Text: 2026 Apr
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