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Postnatal reduction of eIF4E overexpression in D1-SPNs ameliorates KCNQ channel dysfunction, hyperexcitability and ASD-like behaviours.

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Title: Postnatal reduction of eIF4E overexpression in D1-SPNs ameliorates KCNQ channel dysfunction, hyperexcitability and ASD-like behaviours.
Authors: Aaltonen A; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden., Tamaki A; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden., Peris Ramón A; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden., Borgkvist A; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden. anders.borgkvist@ki.se., Santini E; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden. emanuela.santini@ki.se.
Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2026 Feb 18; Vol. 83 (1). Date of Electronic Publication: 2026 Feb 18.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Postnatal reduction of eIF4E overexpression in D1-SPNs ameliorates KCNQ channel dysfunction, hyperexcitability and ASD-like behaviours.
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  Data: <searchLink fieldCode="AU" term="%22Aaltonen+A%22">Aaltonen A</searchLink>; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Tamaki+A%22">Tamaki A</searchLink>; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Peris+Ramón+A%22">Peris Ramón A</searchLink>; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Borgkvist+A%22">Borgkvist A</searchLink>; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden. anders.borgkvist@ki.se.<br /><searchLink fieldCode="AU" term="%22Santini+E%22">Santini E</searchLink>; Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden. emanuela.santini@ki.se.
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  Data: <searchLink fieldCode="JN" term="%229705402%22">Cellular and molecular life sciences : CMLS</searchLink> [Cell Mol Life Sci] 2026 Feb 18; Vol. 83 (1). <i>Date of Electronic Publication: </i>2026 Feb 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>9705402 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1420-9071 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221420682X%22">1420682X </searchLink><i>NLM ISO Abbreviation: </i>Cell Mol Life Sci <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s00018-026-06115-2
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      – Code: eng
        Text: English
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      – TitleFull: Postnatal reduction of eIF4E overexpression in D1-SPNs ameliorates KCNQ channel dysfunction, hyperexcitability and ASD-like behaviours.
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              Text: 2026 Feb 18
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