A brain-enriched circRNA blood biomarker can predict response to SSRI antidepressants.

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Title: A brain-enriched circRNA blood biomarker can predict response to SSRI antidepressants.
Authors: Papageorgiou G; Circular Genomics Inc., San Diego, CA, USA.; University of New Mexico, Department of Neurosciences, Albuquerque, NM, USA., Ibrahim EC; Aix-Marseille Univ, CNRS, INT, Inst Neurosci Timone, Marseille, France.; Fondation FondaMental, Créteil, France., Gorgievski V; Université Paris Cité, Inserm, CNRS, HealthFex, F-75006, Paris, France., Maxson G; Circular Genomics Inc., San Diego, CA, USA., Lozano E; Circular Genomics Inc., San Diego, CA, USA., Gordon E; Circular Genomics Inc., San Diego, CA, USA., Lefrere A; Fondation FondaMental, Créteil, France.; Hôpital Sainte Marguerite AP-HM, Pôle de Psychiatrie, Marseille, France., Toupet MJ; Hôpital Sainte Marguerite AP-HM, Pôle de Psychiatrie, Marseille, France., Courtet P; Fondation FondaMental, Créteil, France.; IGF, Université de Montpellier, CNRS, INSERM, Montpellier, France.; Department of Emergency Psychiatry and Acute Care, Lapeyronie Hospital, CHU Montpellier, Montpellier, France., Belzeaux R; Fondation FondaMental, Créteil, France.; IGF, Université de Montpellier, CNRS, INSERM, Montpellier, France.; Department of Psychiatry, CHU de Montpellier, Montpellier, France., Foster J; University of Texas Southwestern Medical Center, Department of Psychiatry, Dallas, TX, USA., Carmody T; University of Texas Southwestern Medical Center, Department of Psychiatry, Dallas, TX, USA., Perlis RH; Center for Quantitative Health, Massachusetts General Hospital, Boston, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA., Trivedi MH; University of Texas Southwestern Medical Center, Department of Psychiatry, Dallas, TX, USA. Madhukar.Trivedi@UTSouthwestern.edu., Tzavara ET; Fondation FondaMental, Créteil, France. eleni.tzavara@inserm.fr.; Université Paris Cité, Inserm, CNRS, HealthFex, F-75006, Paris, France. eleni.tzavara@inserm.fr.; Hôpital Sainte Marguerite AP-HM, Pôle de Psychiatrie, Marseille, France. eleni.tzavara@inserm.fr., Mellios N; Circular Genomics Inc., San Diego, CA, USA. nmellios@circulargenomics.com.; University of New Mexico, Department of Neurosciences, Albuquerque, NM, USA. nmellios@circulargenomics.com.
Source: Molecular psychiatry [Mol Psychiatry] 2026 Jul; Vol. 31 (7), pp. 3637-3652. Date of Electronic Publication: 2026 Feb 17.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-5578
DOI:10.1038/s41380-026-03491-w