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A brain-enriched circRNA blood biomarker can predict response to SSRI antidepressants.

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Title: A brain-enriched circRNA blood biomarker can predict response to SSRI antidepressants.
Authors: Papageorgiou G; Circular Genomics Inc., San Diego, CA, USA.; University of New Mexico, Department of Neurosciences, Albuquerque, NM, USA., Ibrahim EC; Aix-Marseille Univ, CNRS, INT, Inst Neurosci Timone, Marseille, France.; Fondation FondaMental, Créteil, France., Gorgievski V; Université Paris Cité, Inserm, CNRS, HealthFex, F-75006, Paris, France., Maxson G; Circular Genomics Inc., San Diego, CA, USA., Lozano E; Circular Genomics Inc., San Diego, CA, USA., Gordon E; Circular Genomics Inc., San Diego, CA, USA., Lefrere A; Fondation FondaMental, Créteil, France.; Hôpital Sainte Marguerite AP-HM, Pôle de Psychiatrie, Marseille, France., Toupet MJ; Hôpital Sainte Marguerite AP-HM, Pôle de Psychiatrie, Marseille, France., Courtet P; Fondation FondaMental, Créteil, France.; IGF, Université de Montpellier, CNRS, INSERM, Montpellier, France.; Department of Emergency Psychiatry and Acute Care, Lapeyronie Hospital, CHU Montpellier, Montpellier, France., Belzeaux R; Fondation FondaMental, Créteil, France.; IGF, Université de Montpellier, CNRS, INSERM, Montpellier, France.; Department of Psychiatry, CHU de Montpellier, Montpellier, France., Foster J; University of Texas Southwestern Medical Center, Department of Psychiatry, Dallas, TX, USA., Carmody T; University of Texas Southwestern Medical Center, Department of Psychiatry, Dallas, TX, USA., Perlis RH; Center for Quantitative Health, Massachusetts General Hospital, Boston, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA., Trivedi MH; University of Texas Southwestern Medical Center, Department of Psychiatry, Dallas, TX, USA. Madhukar.Trivedi@UTSouthwestern.edu., Tzavara ET; Fondation FondaMental, Créteil, France. eleni.tzavara@inserm.fr.; Université Paris Cité, Inserm, CNRS, HealthFex, F-75006, Paris, France. eleni.tzavara@inserm.fr.; Hôpital Sainte Marguerite AP-HM, Pôle de Psychiatrie, Marseille, France. eleni.tzavara@inserm.fr., Mellios N; Circular Genomics Inc., San Diego, CA, USA. nmellios@circulargenomics.com.; University of New Mexico, Department of Neurosciences, Albuquerque, NM, USA. nmellios@circulargenomics.com.
Source: Molecular psychiatry [Mol Psychiatry] 2026 Jul; Vol. 31 (7), pp. 3637-3652. Date of Electronic Publication: 2026 Feb 17.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A brain-enriched circRNA blood biomarker can predict response to SSRI antidepressants.
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  Data: <searchLink fieldCode="AU" term="%22Papageorgiou+G%22">Papageorgiou G</searchLink>; Circular Genomics Inc., San Diego, CA, USA.; University of New Mexico, Department of Neurosciences, Albuquerque, NM, USA.<br /><searchLink fieldCode="AU" term="%22Ibrahim+EC%22">Ibrahim EC</searchLink>; Aix-Marseille Univ, CNRS, INT, Inst Neurosci Timone, Marseille, France.; Fondation FondaMental, Créteil, France.<br /><searchLink fieldCode="AU" term="%22Gorgievski+V%22">Gorgievski V</searchLink>; Université Paris Cité, Inserm, CNRS, HealthFex, F-75006, Paris, France.<br /><searchLink fieldCode="AU" term="%22Maxson+G%22">Maxson G</searchLink>; Circular Genomics Inc., San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lozano+E%22">Lozano E</searchLink>; Circular Genomics Inc., San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gordon+E%22">Gordon E</searchLink>; Circular Genomics Inc., San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lefrere+A%22">Lefrere A</searchLink>; Fondation FondaMental, Créteil, France.; Hôpital Sainte Marguerite AP-HM, Pôle de Psychiatrie, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Toupet+MJ%22">Toupet MJ</searchLink>; Hôpital Sainte Marguerite AP-HM, Pôle de Psychiatrie, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Courtet+P%22">Courtet P</searchLink>; Fondation FondaMental, Créteil, France.; IGF, Université de Montpellier, CNRS, INSERM, Montpellier, France.; Department of Emergency Psychiatry and Acute Care, Lapeyronie Hospital, CHU Montpellier, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Belzeaux+R%22">Belzeaux R</searchLink>; Fondation FondaMental, Créteil, France.; IGF, Université de Montpellier, CNRS, INSERM, Montpellier, France.; Department of Psychiatry, CHU de Montpellier, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Foster+J%22">Foster J</searchLink>; University of Texas Southwestern Medical Center, Department of Psychiatry, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Carmody+T%22">Carmody T</searchLink>; University of Texas Southwestern Medical Center, Department of Psychiatry, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Perlis+RH%22">Perlis RH</searchLink>; Center for Quantitative Health, Massachusetts General Hospital, Boston, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Trivedi+MH%22">Trivedi MH</searchLink>; University of Texas Southwestern Medical Center, Department of Psychiatry, Dallas, TX, USA. Madhukar.Trivedi@UTSouthwestern.edu.<br /><searchLink fieldCode="AU" term="%22Tzavara+ET%22">Tzavara ET</searchLink>; Fondation FondaMental, Créteil, France. eleni.tzavara@inserm.fr.; Université Paris Cité, Inserm, CNRS, HealthFex, F-75006, Paris, France. eleni.tzavara@inserm.fr.; Hôpital Sainte Marguerite AP-HM, Pôle de Psychiatrie, Marseille, France. eleni.tzavara@inserm.fr.<br /><searchLink fieldCode="AU" term="%22Mellios+N%22">Mellios N</searchLink>; Circular Genomics Inc., San Diego, CA, USA. nmellios@circulargenomics.com.; University of New Mexico, Department of Neurosciences, Albuquerque, NM, USA. nmellios@circulargenomics.com.
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  Data: <searchLink fieldCode="JN" term="%229607835%22">Molecular psychiatry</searchLink> [Mol Psychiatry] 2026 Jul; Vol. 31 (7), pp. 3637-3652. <i>Date of Electronic Publication: </i>2026 Feb 17.
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