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The use of non-TNF targeted biologics in Behçet's disease: real-life data from the International AIDA Network Behçet's Disease Registry.

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Title: The use of non-TNF targeted biologics in Behçet's disease: real-life data from the International AIDA Network Behçet's Disease Registry.
Authors: Sevik G; Department of Internal Medicine, Division of Rheumatology, Faculty of Medicine, Marmara University, Istanbul, Turkey., Lopalco G; Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), Policlinic Hospital, University of Bari, Bari, Italy., Iannone F; Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), Policlinic Hospital, University of Bari, Bari, Italy., Frassi M; Rheumatology and Clinical Immunology, Spedali Civili and Department of Clinical and Experimental Sciences, University of Brescia, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Brescia, Italy., Piga M; Rheumatology Unit, Department of Medical Sciences and Public Health, University and AOU of Cagliari, Cagliari, Italy., Emmi G; Clinical Medicine and Rheumatology Unit, Cattinara University Hospital, Trieste, Italy.; Department of Medicine, Centre for Inflammatory Diseases, Monash Medical Centre, Monash University, Melbourne, Australia., Ruscitti P; Rheumatology Unit, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy., Ciccia F; Department of Precision Medicine, Università Degli Studi Della Campania Luigi Vanvitelli, Naples, Italy., Viapiana O; Rheumatology Unit, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy., Tufan A; Division of Rheumatology, Department of Internal Medicine, Gazi University Hospital, Ankara, Turkey., Giacomelli R; Clinical Unit of Immunorheumatology, Fondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy.; Research Unit of Immunorheumatology, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Roma, Italy., Insalaco A; Division of Rheumatology, Ospedale Pediatrico Bambino Gesù, IRCCS [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Rome, Italy., Almaghlouth I; Rheumatology Unit, Department of Medicine, King Saud University, Riyadh, Saudi Arabia., Carubbi F; University of L'Aquila, Department of Life, Health & Environmental Sciences, Internal Medicine and Nephrology Division, ASL1 Avezzano-Sulmona-L'Aquila, San Salvatore Hospital, L'Aquila, Italy., González-García A; Systemic Autoimmune Diseases Unit, Department of Internal Medicine, Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain., Conforti A; U.O. Medicina Generale, Ospedale San Paolo di Civitavecchia, Civitavecchia, Rome, Italy., Talarico R; Rheumatology Unit, Azienda Ospedaliero Universitaria Pisana, University of Pisa, Pisa, Italy., Ragab G; Internal Medicine Department, Rheumatology and Clinical Immunology Unit, Faculty of Medicine, Cairo University, Giza, Egypt.; Faculty of Medicine, Newgiza University, 6th of October City, Egypt., Gentileschi S; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy.; Azienda Ospedaliero-Universitaria Senese, European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center, Siena, Italy., Caggiano V; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy.; Azienda Ospedaliero-Universitaria Senese, European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center, Siena, Italy., Sota J; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy.; Azienda Ospedaliero-Universitaria Senese, European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center, Siena, Italy., Fabiani C; Azienda Ospedaliero-Universitaria Senese, European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center, Siena, Italy.; Ophthalmology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy., Vitale A; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy.; Azienda Ospedaliero-Universitaria Senese, European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center, Siena, Italy., Cantarini L; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy.; Azienda Ospedaliero-Universitaria Senese, European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center, Siena, Italy., Direskeneli H; Department of Internal Medicine, Division of Rheumatology, Faculty of Medicine, Marmara University, Istanbul, Turkey., Alibaz-Oner F; Department of Internal Medicine, Division of Rheumatology, Faculty of Medicine, Marmara University, Istanbul, Turkey.
Source: Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2026 May 05; Vol. 65 (5).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 100883501 Publication Model: Print Cited Medium: Internet ISSN: 1462-0332 (Electronic) Linking ISSN: 14620324 NLM ISO Abbreviation: Rheumatology (Oxford) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The use of non-TNF targeted biologics in Behçet's disease: real-life data from the International AIDA Network Behçet's Disease Registry.
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  Data: <searchLink fieldCode="AU" term="%22Sevik+G%22">Sevik G</searchLink>; Department of Internal Medicine, Division of Rheumatology, Faculty of Medicine, Marmara University, Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Lopalco+G%22">Lopalco G</searchLink>; Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), Policlinic Hospital, University of Bari, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Iannone+F%22">Iannone F</searchLink>; Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), Policlinic Hospital, University of Bari, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Frassi+M%22">Frassi M</searchLink>; Rheumatology and Clinical Immunology, Spedali Civili and Department of Clinical and Experimental Sciences, University of Brescia, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Piga+M%22">Piga M</searchLink>; Rheumatology Unit, Department of Medical Sciences and Public Health, University and AOU of Cagliari, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Emmi+G%22">Emmi G</searchLink>; Clinical Medicine and Rheumatology Unit, Cattinara University Hospital, Trieste, Italy.; Department of Medicine, Centre for Inflammatory Diseases, Monash Medical Centre, Monash University, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Ruscitti+P%22">Ruscitti P</searchLink>; Rheumatology Unit, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.<br /><searchLink fieldCode="AU" term="%22Ciccia+F%22">Ciccia F</searchLink>; Department of Precision Medicine, Università Degli Studi Della Campania Luigi Vanvitelli, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Viapiana+O%22">Viapiana O</searchLink>; Rheumatology Unit, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Tufan+A%22">Tufan A</searchLink>; Division of Rheumatology, Department of Internal Medicine, Gazi University Hospital, Ankara, Turkey.<br /><searchLink fieldCode="AU" term="%22Giacomelli+R%22">Giacomelli R</searchLink>; Clinical Unit of Immunorheumatology, Fondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy.; Research Unit of Immunorheumatology, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Insalaco+A%22">Insalaco A</searchLink>; Division of Rheumatology, Ospedale Pediatrico Bambino Gesù, IRCCS [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Almaghlouth+I%22">Almaghlouth I</searchLink>; Rheumatology Unit, Department of Medicine, King Saud University, Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Carubbi+F%22">Carubbi F</searchLink>; University of L'Aquila, Department of Life, Health & Environmental Sciences, Internal Medicine and Nephrology Division, ASL1 Avezzano-Sulmona-L'Aquila, San Salvatore Hospital, L'Aquila, Italy.<br /><searchLink fieldCode="AU" term="%22González-García+A%22">González-García A</searchLink>; Systemic Autoimmune Diseases Unit, Department of Internal Medicine, Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Conforti+A%22">Conforti A</searchLink>; U.O. Medicina Generale, Ospedale San Paolo di Civitavecchia, Civitavecchia, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Talarico+R%22">Talarico R</searchLink>; Rheumatology Unit, Azienda Ospedaliero Universitaria Pisana, University of Pisa, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Ragab+G%22">Ragab G</searchLink>; Internal Medicine Department, Rheumatology and Clinical Immunology Unit, Faculty of Medicine, Cairo University, Giza, Egypt.; Faculty of Medicine, Newgiza University, 6th of October City, Egypt.<br /><searchLink fieldCode="AU" term="%22Gentileschi+S%22">Gentileschi S</searchLink>; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy.; Azienda Ospedaliero-Universitaria Senese, European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Caggiano+V%22">Caggiano V</searchLink>; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy.; Azienda Ospedaliero-Universitaria Senese, European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Sota+J%22">Sota J</searchLink>; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy.; Azienda Ospedaliero-Universitaria Senese, European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Fabiani+C%22">Fabiani C</searchLink>; Azienda Ospedaliero-Universitaria Senese, European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center, Siena, Italy.; Ophthalmology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Vitale+A%22">Vitale A</searchLink>; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy.; Azienda Ospedaliero-Universitaria Senese, European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Cantarini+L%22">Cantarini L</searchLink>; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy.; Azienda Ospedaliero-Universitaria Senese, European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Direskeneli+H%22">Direskeneli H</searchLink>; Department of Internal Medicine, Division of Rheumatology, Faculty of Medicine, Marmara University, Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Alibaz-Oner+F%22">Alibaz-Oner F</searchLink>; Department of Internal Medicine, Division of Rheumatology, Faculty of Medicine, Marmara University, Istanbul, Turkey.
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