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Systemic Manifestations and Mortality Risk in Transthyretin V142I Variant Carriers: A Million Veteran Program Analysis.

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Title: Systemic Manifestations and Mortality Risk in Transthyretin V142I Variant Carriers: A Million Veteran Program Analysis.
Authors: Sideris K; Department of Internal Medicine, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah, USA; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA., Nelson TJ; Veterans Affairs Informatics and Computing Infrastructure, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah, USA., Brinker L; Department of Internal Medicine, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah, USA; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA., Gao A; Veterans Affairs Informatics and Computing Infrastructure, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah, USA., Tcheandjieu C; VA Palo Alto Health Care System, Palo Alto, California, USA; Gladstone Institute of Data Science and Biotechnology, Gladstone Institutes, San Francisco, California, USA; Department of Epidemiology and Biostatistics, University of California-San Francisco, San Francisco, California, USA., Kyriakopoulos CP; Department of Internal Medicine, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah, USA; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA., Berlowitz D; Department of Public Health, Bedford VA Hospital, Bedford, Massachusetts, USA; Department of Public Health, University of Massachusetts Lowell, Lowell, Massachusetts, USA; Department of Medicine, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, USA., Hull L; Division of General Internal Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA; Department of Medicine, Harvard Medical School, Cambridge, Massachusetts, USA., Ferraro JP; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA; Veterans Affairs Informatics and Computing Infrastructure, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah, USA., Agiri FY; Veterans Affairs Informatics and Computing Infrastructure, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah, USA., Pridgen KM; Veterans Affairs Informatics and Computing Infrastructure, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah, USA., Roblin S; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA., Joseph J; Cardiology Section, VA Providence Healthcare System, Providence, Rhode Island, USA; Department of Medicine, Brown University, Providence, Rhode Island, USA., Damrauer SM; Department of Surgery, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania, USA; Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA; Department of Internal Medicine, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania, USA; Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Chang KM; Department of Internal Medicine, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania, USA; Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Teerlink CC; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA; Veterans Affairs Informatics and Computing Infrastructure, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah, USA., Stehlik J; Department of Internal Medicine, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah, USA; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA., Carter S; Department of Internal Medicine, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah, USA; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA., Lynch JA; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA; Veterans Affairs Informatics and Computing Infrastructure, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah, USA. Electronic address: julie.lynch@utah.edu.
Source: JACC. CardioOncology [JACC CardioOncol] 2026 Feb; Vol. 8 (1), pp. 31-44.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101761697 Publication Model: Print Cited Medium: Internet ISSN: 2666-0873 (Electronic) Linking ISSN: 26660873 NLM ISO Abbreviation: JACC CardioOncol Subsets: PubMed not MEDLINE
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  Data: Systemic Manifestations and Mortality Risk in Transthyretin V142I Variant Carriers: A Million Veteran Program Analysis.
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  Data: <searchLink fieldCode="AU" term="%22Sideris+K%22">Sideris K</searchLink>; Department of Internal Medicine, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah, USA; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA.<br /><searchLink fieldCode="AU" term="%22Nelson+TJ%22">Nelson TJ</searchLink>; Veterans Affairs Informatics and Computing Infrastructure, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah, USA.<br /><searchLink fieldCode="AU" term="%22Brinker+L%22">Brinker L</searchLink>; Department of Internal Medicine, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah, USA; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA.<br /><searchLink fieldCode="AU" term="%22Gao+A%22">Gao A</searchLink>; Veterans Affairs Informatics and Computing Infrastructure, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah, USA.<br /><searchLink fieldCode="AU" term="%22Tcheandjieu+C%22">Tcheandjieu C</searchLink>; VA Palo Alto Health Care System, Palo Alto, California, USA; Gladstone Institute of Data Science and Biotechnology, Gladstone Institutes, San Francisco, California, USA; Department of Epidemiology and Biostatistics, University of California-San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Kyriakopoulos+CP%22">Kyriakopoulos CP</searchLink>; Department of Internal Medicine, George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah, USA; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA.<br /><searchLink fieldCode="AU" term="%22Berlowitz+D%22">Berlowitz D</searchLink>; Department of Public Health, Bedford VA Hospital, Bedford, Massachusetts, USA; Department of Public Health, University of Massachusetts Lowell, Lowell, Massachusetts, USA; Department of Medicine, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Hull+L%22">Hull L</searchLink>; Division of General Internal Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA; Department of Medicine, Harvard Medical School, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Ferraro+JP%22">Ferraro JP</searchLink>; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA; Veterans Affairs Informatics and Computing Infrastructure, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah, USA.<br /><searchLink fieldCode="AU" term="%22Agiri+FY%22">Agiri FY</searchLink>; Veterans Affairs Informatics and Computing Infrastructure, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah, USA.<br /><searchLink fieldCode="AU" term="%22Pridgen+KM%22">Pridgen KM</searchLink>; Veterans Affairs Informatics and Computing Infrastructure, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah, USA.<br /><searchLink fieldCode="AU" term="%22Roblin+S%22">Roblin S</searchLink>; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Joseph+J%22">Joseph J</searchLink>; Cardiology Section, VA Providence Healthcare System, Providence, Rhode Island, USA; Department of Medicine, Brown University, Providence, Rhode Island, USA.<br /><searchLink fieldCode="AU" term="%22Damrauer+SM%22">Damrauer SM</searchLink>; Department of Surgery, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania, USA; Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA; Department of Internal Medicine, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania, USA; Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Chang+KM%22">Chang KM</searchLink>; Department of Internal Medicine, Corporal Michael J. 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Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah, USA; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA.<br /><searchLink fieldCode="AU" term="%22Lynch+JA%22">Lynch JA</searchLink>; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA; Veterans Affairs Informatics and Computing Infrastructure, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, Utah, USA. Electronic address: julie.lynch@utah.edu.
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              Text: 2026 Feb
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