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Differential targeting of human pyroptotic caspase-5 and caspase-4 by Shigella OspC2 and OspC3.

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Title: Differential targeting of human pyroptotic caspase-5 and caspase-4 by Shigella OspC2 and OspC3.
Authors: Kim K; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA., Valdespino Diaz MA; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA., Karr RM; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA., Muscolo ME; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA., Goers L; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA., Yu T; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA., Levin TC; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Pruneda JN; Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, Oregon, USA.; Department of Chemical Physiology and Biochemistry, Oregon Health & Science University, Portland, Oregon, USA.; Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA., Lesser CF; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.; Stuart B Levy Center for the Integrated Management of Antimicrobial Resistance, Tufts University, Boston, Massachusetts, USA.
Source: MBio [mBio] 2026 Mar 11; Vol. 17 (3), pp. e0385525. Date of Electronic Publication: 2026 Feb 18.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Differential targeting of human pyroptotic caspase-5 and caspase-4 by Shigella OspC2 and OspC3.
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  Data: <searchLink fieldCode="AU" term="%22Kim+K%22">Kim K</searchLink>; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Valdespino+Diaz+MA%22">Valdespino Diaz MA</searchLink>; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Karr+RM%22">Karr RM</searchLink>; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Muscolo+ME%22">Muscolo ME</searchLink>; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Goers+L%22">Goers L</searchLink>; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Yu+T%22">Yu T</searchLink>; Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Levin+TC%22">Levin TC</searchLink>; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Pruneda+JN%22">Pruneda JN</searchLink>; Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, Oregon, USA.; Department of Chemical Physiology and Biochemistry, Oregon Health & Science University, Portland, Oregon, USA.; Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Lesser+CF%22">Lesser CF</searchLink>; Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.; Stuart B Levy Center for the Integrated Management of Antimicrobial Resistance, Tufts University, Boston, Massachusetts, USA.
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              Text: 2026 Mar 11
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