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High-Dose Influenza Vaccination in Atherosclerotic Cardiovascular Disease: A Multinational Pooled Analysis of DANFLU-2 and GALFLU (FLUNITY-HD).

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Title: High-Dose Influenza Vaccination in Atherosclerotic Cardiovascular Disease: A Multinational Pooled Analysis of DANFLU-2 and GALFLU (FLUNITY-HD).
Authors: Pareek M; Department of Cardiology, Copenhagen University Hospital-Herlev and Gentofte, Copenhagen, Denmark; Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Johansen ND; Department of Cardiology, Copenhagen University Hospital-Herlev and Gentofte, Copenhagen, Denmark; Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Modin D; Department of Cardiology, Copenhagen University Hospital-Herlev and Gentofte, Copenhagen, Denmark; Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Pardo-Seco J; Genetics, Vaccines and Infectious Diseases Research Group, Instituto de Investigación Sanitaria de Santiago de Compostela, Santiago de Compostela, Galicia, Spain; WHO Collaborating Center for Vaccine Safety, Santiago de Compostela, Galicia, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain; GenPoB Research Group, Instituto de Investigación Sanitaria, Hospital Clínico Universitario de Santiago (SERGAS), and INCIFOR, Universidade de Santiago de Compostela, Santiago de Compostela, Galicia, Spain., Rodriguez-Tenreiro-Sánchez C; Genetics, Vaccines and Infectious Diseases Research Group, Instituto de Investigación Sanitaria de Santiago de Compostela, Santiago de Compostela, Galicia, Spain; WHO Collaborating Center for Vaccine Safety, Santiago de Compostela, Galicia, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain; Translational Pediatrics and Infectious Diseases, Hospital Clínico Universitario de Santiago (SERGAS) and University of Santiago de Compostela, Santiago de Compostela, Galicia, Spain., Loiacono MM; Sanofi, Morristown, New Jersey, USA; Department of Epidemiology, University of Delaware, Newark, Delaware, USA., Harris RC; Sanofi, Singapore., Dufournet M; Sanofi, Lyon, France., van Aalst R; Sanofi, Morristown, New Jersey, USA., Chit A; Sanofi, Morristown, New Jersey, USA; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada., Larsen CS; Department of Clinical Medicine-Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark; Danske Lægers Vaccinations Service, European LifeCare Group, Søborg, Denmark., Larsen L; Department of Infectious Diseases, Odense University Hospital, Odense, Denmark., Wiese L; Department of Infectious Diseases, Zealand University Hospital, Roskilde, Denmark., Dalager-Pedersen M; Department of Infectious Diseases, Aalborg University Hospital, Aalborg, Denmark; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark., Claggett BL; Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Janstrup KH; Department of Cardiology, Copenhagen University Hospital-Herlev and Gentofte, Copenhagen, Denmark; Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Duran-Parrondo C; Dirección Xeral de Saúde Pública, Consellería de Sanidade, Xunta de Galicia, Galicia, Spain., Piñeiro-Sotelo M; Department of Communicable Diseases, Dirección Xeral de Saúde Pública, Consellería de Sanidade, Xunta de Galicia, Galicia, Spain., Cribeiro-González M; Department of Communicable Diseases, Dirección Xeral de Saúde Pública, Consellería de Sanidade, Xunta de Galicia, Galicia, Spain., Conde-Pájaro M; Dirección Xeral de Recursos Económicos, Servizo Galego de Saúde, Xunta de Galicia, Galicia, Spain., Mirás-Carballal S; Department of Epidemiology, Dirección Xeral de Saúde Pública, Consellería de Sanidade, Xunta de Galicia, Galicia, Spain., González-Pérez JM; Subdirección de Sistemas y Tecnologías de la Información, Consellería de Sanidade, Xunta de Galicia, Galicia, Spain., Solomon SD; Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Sivapalan P; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Respiratory Medicine Section, Department of Medicine, Copenhagen University Hospital-Herlev and Gentofte, Copenhagen, Denmark., Martel CJ; Statens Serum Institut, Copenhagen, Denmark., Jensen JUS; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Respiratory Medicine Section, Department of Medicine, Copenhagen University Hospital-Herlev and Gentofte, Copenhagen, Denmark., Martinón-Torres F; Genetics, Vaccines and Infectious Diseases Research Group, Instituto de Investigación Sanitaria de Santiago de Compostela, Santiago de Compostela, Galicia, Spain; WHO Collaborating Center for Vaccine Safety, Santiago de Compostela, Galicia, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain; Translational Pediatrics and Infectious Diseases, Hospital Clínico Universitario de Santiago (SERGAS) and University of Santiago de Compostela, Santiago de Compostela, Galicia, Spain., Biering-Sørensen T; Department of Cardiology, Copenhagen University Hospital-Herlev and Gentofte, Copenhagen, Denmark; Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Cardiology, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark; Steno Diabetes Center Copenhagen, Herlev, Denmark. Electronic address: tor.biering@gmail.com.
Corporate Authors: DANFLU-2 Study Group and GALFLU Trial Team
Source: Journal of the American College of Cardiology [J Am Coll Cardiol] 2026 Feb 09. Date of Electronic Publication: 2026 Feb 09.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Biomedical Country of Publication: United States NLM ID: 8301365 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-3597 (Electronic) Linking ISSN: 07351097 NLM ISO Abbreviation: J Am Coll Cardiol Subsets: MEDLINE
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Genetics, Vaccines and Infectious Diseases Research Group, Instituto de Investigación Sanitaria de Santiago de Compostela, Santiago de Compostela, Galicia, Spain; WHO Collaborating Center for Vaccine Safety, Santiago de Compostela, Galicia, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain; GenPoB Research Group, Instituto de Investigación Sanitaria, Hospital Clínico Universitario de Santiago (SERGAS), and INCIFOR, Universidade de Santiago de Compostela, Santiago de Compostela, Galicia, Spain.<br /><searchLink fieldCode="AU" term="%22Rodriguez-Tenreiro-Sánchez+C%22">Rodriguez-Tenreiro-Sánchez C</searchLink>; Genetics, Vaccines and Infectious Diseases Research Group, Instituto de Investigación Sanitaria de Santiago de Compostela, Santiago de Compostela, Galicia, Spain; WHO Collaborating Center for Vaccine Safety, Santiago de Compostela, Galicia, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain; 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Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Duran-Parrondo+C%22">Duran-Parrondo C</searchLink>; Dirección Xeral de Saúde Pública, Consellería de Sanidade, Xunta de Galicia, Galicia, Spain.<br /><searchLink fieldCode="AU" term="%22Piñeiro-Sotelo+M%22">Piñeiro-Sotelo M</searchLink>; Department of Communicable Diseases, Dirección Xeral de Saúde Pública, Consellería de Sanidade, Xunta de Galicia, Galicia, Spain.<br /><searchLink fieldCode="AU" term="%22Cribeiro-González+M%22">Cribeiro-González M</searchLink>; Department of Communicable Diseases, Dirección Xeral de Saúde Pública, Consellería de Sanidade, Xunta de Galicia, Galicia, Spain.<br /><searchLink fieldCode="AU" term="%22Conde-Pájaro+M%22">Conde-Pájaro M</searchLink>; Dirección Xeral de Recursos Económicos, Servizo Galego de Saúde, Xunta de Galicia, Galicia, Spain.<br /><searchLink fieldCode="AU" term="%22Mirás-Carballal+S%22">Mirás-Carballal S</searchLink>; Department of Epidemiology, Dirección Xeral de Saúde Pública, Consellería de Sanidade, Xunta de Galicia, Galicia, Spain.<br /><searchLink fieldCode="AU" term="%22González-Pérez+JM%22">González-Pérez JM</searchLink>; Subdirección de Sistemas y Tecnologías de la Información, Consellería de Sanidade, Xunta de Galicia, Galicia, Spain.<br /><searchLink fieldCode="AU" term="%22Solomon+SD%22">Solomon SD</searchLink>; Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Sivapalan+P%22">Sivapalan P</searchLink>; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Respiratory Medicine Section, Department of Medicine, Copenhagen University Hospital-Herlev and Gentofte, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Martel+CJ%22">Martel CJ</searchLink>; Statens Serum Institut, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Jensen+JUS%22">Jensen JUS</searchLink>; 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Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Cardiology, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark; Steno Diabetes Center Copenhagen, Herlev, Denmark. Electronic address: tor.biering@gmail.com.
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