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BDNF Val66Met protects oxaliplatin-induced peripheral neuropathy in patients with colorectal cancer.

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Title: BDNF Val66Met protects oxaliplatin-induced peripheral neuropathy in patients with colorectal cancer.
Authors: Chen LH; Department of Pharmacology, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.; Department of Obstetrics and Gynecology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70403, Taiwan.; University Center of Bioscience and Biotechnology, National Cheng Kung University, Tainan 70101, Taiwan., Lin PC; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70403, Taiwan.; Department of Genomic Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70403, Taiwan., Yeh YM; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70403, Taiwan., Li CI; Department of Statistics, College of Management, National Cheng Kung University, Tainan 70101, Taiwan., Chang LY; Department of Pharmacology, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan., Chang JY; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli County 35053, Taiwan.; TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taipei 11031, Taiwan., Shen MR; Department of Pharmacology, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.; Department of Obstetrics and Gynecology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70403, Taiwan.
Source: Science translational medicine [Sci Transl Med] 2026 Feb 18; Vol. 18 (837), pp. eadx1436. Date of Electronic Publication: 2026 Feb 18.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: BDNF Val<superscript>66</superscript>Met protects oxaliplatin-induced peripheral neuropathy in patients with colorectal cancer.
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  Data: <searchLink fieldCode="AU" term="%22Chen+LH%22">Chen LH</searchLink>; Department of Pharmacology, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.; Department of Obstetrics and Gynecology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70403, Taiwan.; University Center of Bioscience and Biotechnology, National Cheng Kung University, Tainan 70101, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+PC%22">Lin PC</searchLink>; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70403, Taiwan.; Department of Genomic Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70403, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yeh+YM%22">Yeh YM</searchLink>; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70403, Taiwan.<br /><searchLink fieldCode="AU" term="%22Li+CI%22">Li CI</searchLink>; Department of Statistics, College of Management, National Cheng Kung University, Tainan 70101, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+LY%22">Chang LY</searchLink>; Department of Pharmacology, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+JY%22">Chang JY</searchLink>; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli County 35053, Taiwan.; TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taipei 11031, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shen+MR%22">Shen MR</searchLink>; Department of Pharmacology, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.; Department of Obstetrics and Gynecology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70403, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2026 Feb 18; Vol. 18 (837), pp. eadx1436. <i>Date of Electronic Publication: </i>2026 Feb 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101505086 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1946-6242 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219466234%22">19466234 </searchLink><i>NLM ISO Abbreviation: </i>Sci Transl Med <i>Subsets: </i>MEDLINE
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        Value: 10.1126/scitranslmed.adx1436
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        Text: English
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      – TitleFull: BDNF Val66Met protects oxaliplatin-induced peripheral neuropathy in patients with colorectal cancer.
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              Text: 2026 Feb 18
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