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Development of a current Good Manufacturing Practice-compliant Process for Producing Cryptosporidium parvum oocysts for Clinical Use.

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Title: Development of a current Good Manufacturing Practice-compliant Process for Producing Cryptosporidium parvum oocysts for Clinical Use.
Authors: Jumani RS; Global Health, Biomedical Research, Novartis, Emeryville, California, USA., Thomas B; Global Health, Biomedical Research, Novartis, Emeryville, California, USA., Lakshman J; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA., Ostermeier C; Novartis Pharmaceuticals Corporation, Basel, Switzerland., Nuber N; Novartis Pharmaceuticals Corporation, Basel, Switzerland., Blusch JH; Novartis Pharmaceuticals Corporation, Basel, Switzerland., Braud-Perez S; Novartis Pharmaceuticals Corporation, Basel, Switzerland., Wetty D; Novartis Pharmaceuticals Corporation, Cambridge, Massachusetts, USA., Nouaime L; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA., Dederichs J; Novartis Pharmaceuticals Corporation, Basel, Switzerland., Etse J; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA., Grubesic S; Novartis Pharmaceuticals Corporation, Basel, Switzerland., Lakshminarayana SB; Global Health, Biomedical Research, Novartis, Emeryville, California, USA., Watson LC; Global Health, Biomedical Research, Novartis, Emeryville, California, USA., Blais J; Global Health, Biomedical Research, Novartis, Emeryville, California, USA., Thompson Z; Charles River Laboratories, Biological Testing Solutions, Wayne, Pennsylvania, USA., Jaber TZ; Charles River Laboratories, Biological Testing Solutions, Wayne, Pennsylvania, USA., Jones MR; Charles River Laboratories, Biological Testing Solutions, Wayne, Pennsylvania, USA., Schaefer DA; School of Animal and Comparative Biomedical Sciences, The University of Arizona, Tucson, Arizona, USA., Riggs MW; School of Animal and Comparative Biomedical Sciences, The University of Arizona, Tucson, Arizona, USA., Huston CD; Department of Medicine, University of Vermont Larner College of Medicine, Burlington, Vermont, USA., Diagana TT; Global Health, Biomedical Research, Novartis, Emeryville, California, USA., Manjunatha UH; Global Health, Biomedical Research, Novartis, Emeryville, California, USA.
Source: The Journal of infectious diseases [J Infect Dis] 2026 Feb 18. Date of Electronic Publication: 2026 Feb 18.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0413675 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6613 (Electronic) Linking ISSN: 00221899 NLM ISO Abbreviation: J Infect Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Jumani+RS%22">Jumani RS</searchLink>; Global Health, Biomedical Research, Novartis, Emeryville, California, USA.<br /><searchLink fieldCode="AU" term="%22Thomas+B%22">Thomas B</searchLink>; Global Health, Biomedical Research, Novartis, Emeryville, California, USA.<br /><searchLink fieldCode="AU" term="%22Lakshman+J%22">Lakshman J</searchLink>; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Ostermeier+C%22">Ostermeier C</searchLink>; Novartis Pharmaceuticals Corporation, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Nuber+N%22">Nuber N</searchLink>; Novartis Pharmaceuticals Corporation, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Blusch+JH%22">Blusch JH</searchLink>; Novartis Pharmaceuticals Corporation, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Braud-Perez+S%22">Braud-Perez S</searchLink>; Novartis Pharmaceuticals Corporation, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wetty+D%22">Wetty D</searchLink>; Novartis Pharmaceuticals Corporation, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Nouaime+L%22">Nouaime L</searchLink>; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Dederichs+J%22">Dederichs J</searchLink>; Novartis Pharmaceuticals Corporation, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Etse+J%22">Etse J</searchLink>; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Grubesic+S%22">Grubesic S</searchLink>; Novartis Pharmaceuticals Corporation, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Lakshminarayana+SB%22">Lakshminarayana SB</searchLink>; Global Health, Biomedical Research, Novartis, Emeryville, California, USA.<br /><searchLink fieldCode="AU" term="%22Watson+LC%22">Watson LC</searchLink>; Global Health, Biomedical Research, Novartis, Emeryville, California, USA.<br /><searchLink fieldCode="AU" term="%22Blais+J%22">Blais J</searchLink>; Global Health, Biomedical Research, Novartis, Emeryville, California, USA.<br /><searchLink fieldCode="AU" term="%22Thompson+Z%22">Thompson Z</searchLink>; Charles River Laboratories, Biological Testing Solutions, Wayne, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Jaber+TZ%22">Jaber TZ</searchLink>; Charles River Laboratories, Biological Testing Solutions, Wayne, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Jones+MR%22">Jones MR</searchLink>; Charles River Laboratories, Biological Testing Solutions, Wayne, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Schaefer+DA%22">Schaefer DA</searchLink>; School of Animal and Comparative Biomedical Sciences, The University of Arizona, Tucson, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Riggs+MW%22">Riggs MW</searchLink>; School of Animal and Comparative Biomedical Sciences, The University of Arizona, Tucson, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Huston+CD%22">Huston CD</searchLink>; Department of Medicine, University of Vermont Larner College of Medicine, Burlington, Vermont, USA.<br /><searchLink fieldCode="AU" term="%22Diagana+TT%22">Diagana TT</searchLink>; Global Health, Biomedical Research, Novartis, Emeryville, California, USA.<br /><searchLink fieldCode="AU" term="%22Manjunatha+UH%22">Manjunatha UH</searchLink>; Global Health, Biomedical Research, Novartis, Emeryville, California, USA.
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