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PrecISE-a biomarker-stratified adaptive trial of 5 interventions in severe asthma: Final protocol and the baseline cohort.

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Title: PrecISE-a biomarker-stratified adaptive trial of 5 interventions in severe asthma: Final protocol and the baseline cohort.
Authors: Denlinger LC; University of Wisconsin School of Medicine and Public Health, Madison, Wis. Electronic address: lcd@medicine.wisc.edu., Israel E; Brigham and Women's Hospital and Harvard Medical School, Boston, Mass., Moore WC; Wake Forest School of Medicine, Winston-Salem, NC., Georas SN; University of Rochester School of Medicine and Dentistry, Rochester, NY., Wright RJ; Icahn School of Medicine at Mount Sinai, New York, NY., Castro M; University of Kansas School of Medicine, Kansas City, Kan., Peden DB; University of North Carolina, Chapel Hill, NC., Anstrom KJ; University of North Carolina, Chapel Hill, NC., Bleecker ER; Mayo Clinic, Scottsdale, Ariz., Alexander LC; University of California-San Diego School of Medicine, San Diego, Calif., Cahill KN; Vanderbilt University School of Medicine, Nashville, Tenn., Cardet JC; University of South Florida-Morsani College of Medicine, Tampa, Fla., Carr TF; University of Arizona College of Medicine, Tucson, Ariz., Cedano J; University of Kansas School of Medicine, Kansas City, Kan., Chen AY; University of North Carolina, Chapel Hill, NC., Chupp GL; Yale University School of Medicine, New Haven, Conn., Comhair SAA; Cleveland Clinic, Cleveland, Ohio., DiMango EA; Columbia University Vagelos College of Physicians and Surgeons, New York, NY., Erzurum SC; Cleveland Clinic, Cleveland, Ohio., Fahy JV; University of California-San Francisco School of Medicine, San Francisco, Calif., Fajt ML; University of Pittsburgh Schools of Medicine and Public Health, Pittsburgh, Pa., Gaston BM; Indiana University School of Medicine, Indianapolis, Ind., Jackson DJ; University of Wisconsin School of Medicine and Public Health, Madison, Wis., Jain S; University of California-San Diego School of Medicine, San Diego, Calif., Jarjour NN; University of Wisconsin School of Medicine and Public Health, Madison, Wis., Kenyon NJ; University of California-Davis School of Medicine, Sacramento, Calif., Kraft M; Icahn School of Medicine at Mount Sinai, New York, NY., Krishnan JA; University of Illinois-Chicago, Chicago, Ill., Kumar R; Northwestern University Feinberg School of Medicine, Chicago, Ill., Lugogo NL; University of Michigan Medical School, Ann Arbor, Mich., Martinez FD; University of Arizona College of Medicine, Tucson, Ariz., Marquis MA; University of North Carolina, Chapel Hill, NC., Pappalardo AA; University of Illinois-Chicago, Chicago, Ill., Phipatanakul W; Boston Children's Hospital and Harvard Medical School, Boston, Mass., Rank MA; Mayo Clinic, Scottsdale, Ariz., Rosenberg SR; Northwestern University Feinberg School of Medicine, Chicago, Ill., Salciccioli JD; Brigham and Women's Hospital and Harvard Medical School, Boston, Mass., Sanchez M; University of North Carolina, Chapel Hill, NC., Smith LJ; Northwestern University Feinberg School of Medicine, Chicago, Ill., Sumino K; Washington University School of Medicine, St Louis, Mo., Szefler SJ; University of Colorado School of Medicine, Aurora, Colo., Tang M; University of California-San Francisco School of Medicine, San Francisco, Calif., Vijayanand P; University of California-San Diego School of Medicine, San Diego, Calif; La Jolla Institute for Immunology, La Jolla, Calif., Wechsler ME; University of Colorado School of Medicine, Aurora, Colo; National Jewish Health, Denver, Colo., Wenzel SE; University of Pittsburgh Schools of Medicine and Public Health, Pittsburgh, Pa., White SR; University of Chicago Pritzker School of Medicine, Chicago, Ill., Zeki AA; University of California-Davis School of Medicine, Sacramento, Calif., Ivanova A; University of North Carolina, Chapel Hill, NC., Bacharier LB; Vanderbilt University School of Medicine, Nashville, Tenn., Akuthota P; University of California-San Diego School of Medicine, San Diego, Calif.
Corporate Authors: NHLBI PrecISE Study Team
Source: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2026 Jun; Vol. 157 (6), pp. 1261-1273. Date of Electronic Publication: 2026 Feb 16.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 1275002 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6825 (Electronic) Linking ISSN: 00916749 NLM ISO Abbreviation: J Allergy Clin Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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