Macrophage METTL3 synergizes with YTHDF2 to promote atherosclerosis by inhibiting the LXR-α/ABCA1 pathway.

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Title: Macrophage METTL3 synergizes with YTHDF2 to promote atherosclerosis by inhibiting the LXR-α/ABCA1 pathway.
Authors: Tu YF; Department of General Practice, The Fifth Affiliated Hospital of Southern Medical University, 510900, Guangzhou, Guangdong, China., Li Y; Department of General Practice, The Fifth Affiliated Hospital of Southern Medical University, 510900, Guangzhou, Guangdong, China; Guangxi Key Laboratory of Diabetic Systems Medicine, Guilin Medical University, 541199, Guilin, Guangxi, China., Qin JF; Department of General Practice, The Fifth Affiliated Hospital of Southern Medical University, 510900, Guangzhou, Guangdong, China; Guangxi Key Laboratory of Diabetic Systems Medicine, Guilin Medical University, 541199, Guilin, Guangxi, China., Chen WY; Department of General Practice, The Fifth Affiliated Hospital of Southern Medical University, 510900, Guangzhou, Guangdong, China., Zhu X; Department of General Practice, The Fifth Affiliated Hospital of Southern Medical University, 510900, Guangzhou, Guangdong, China; Guangxi Key Laboratory of Diabetic Systems Medicine, Guilin Medical University, 541199, Guilin, Guangxi, China. Electronic address: 1365681080@qq.com., Sammad A; Department of General Practice, The Fifth Affiliated Hospital of Southern Medical University, 510900, Guangzhou, Guangdong, China. Electronic address: drabdulsammad@outlook.com., Yin K; Department of General Practice, The Fifth Affiliated Hospital of Southern Medical University, 510900, Guangzhou, Guangdong, China; Guangxi Key Laboratory of Diabetic Systems Medicine, Guilin Medical University, 541199, Guilin, Guangxi, China. Electronic address: kaiyinby@qq.com.
Source: Nutrition, metabolism, and cardiovascular diseases : NMCD [Nutr Metab Cardiovasc Dis] 2026 May; Vol. 36 (5), pp. 104568. Date of Electronic Publication: 2026 Jan 14.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9111474 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1590-3729 (Electronic) Linking ISSN: 09394753 NLM ISO Abbreviation: Nutr Metab Cardiovasc Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Macrophage METTL3 synergizes with YTHDF2 to promote atherosclerosis by inhibiting the LXR-α/ABCA1 pathway.
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  Data: <searchLink fieldCode="AU" term="%22Tu+YF%22">Tu YF</searchLink>; Department of General Practice, The Fifth Affiliated Hospital of Southern Medical University, 510900, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Department of General Practice, The Fifth Affiliated Hospital of Southern Medical University, 510900, Guangzhou, Guangdong, China; Guangxi Key Laboratory of Diabetic Systems Medicine, Guilin Medical University, 541199, Guilin, Guangxi, China.<br /><searchLink fieldCode="AU" term="%22Qin+JF%22">Qin JF</searchLink>; Department of General Practice, The Fifth Affiliated Hospital of Southern Medical University, 510900, Guangzhou, Guangdong, China; Guangxi Key Laboratory of Diabetic Systems Medicine, Guilin Medical University, 541199, Guilin, Guangxi, China.<br /><searchLink fieldCode="AU" term="%22Chen+WY%22">Chen WY</searchLink>; Department of General Practice, The Fifth Affiliated Hospital of Southern Medical University, 510900, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Zhu+X%22">Zhu X</searchLink>; Department of General Practice, The Fifth Affiliated Hospital of Southern Medical University, 510900, Guangzhou, Guangdong, China; Guangxi Key Laboratory of Diabetic Systems Medicine, Guilin Medical University, 541199, Guilin, Guangxi, China. Electronic address: 1365681080@qq.com.<br /><searchLink fieldCode="AU" term="%22Sammad+A%22">Sammad A</searchLink>; Department of General Practice, The Fifth Affiliated Hospital of Southern Medical University, 510900, Guangzhou, Guangdong, China. Electronic address: drabdulsammad@outlook.com.<br /><searchLink fieldCode="AU" term="%22Yin+K%22">Yin K</searchLink>; Department of General Practice, The Fifth Affiliated Hospital of Southern Medical University, 510900, Guangzhou, Guangdong, China; Guangxi Key Laboratory of Diabetic Systems Medicine, Guilin Medical University, 541199, Guilin, Guangxi, China. Electronic address: kaiyinby@qq.com.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>9111474 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1590-3729 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209394753%22">09394753 </searchLink><i>NLM ISO Abbreviation: </i>Nutr Metab Cardiovasc Dis <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1016/j.numecd.2026.104568
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      – Code: eng
        Text: English
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        StartPage: 104568
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      – TitleFull: Macrophage METTL3 synergizes with YTHDF2 to promote atherosclerosis by inhibiting the LXR-α/ABCA1 pathway.
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            – D: 01
              M: 05
              Text: 2026 May
              Type: published
              Y: 2026
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              Value: 5
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            – TitleFull: Nutrition, metabolism, and cardiovascular diseases : NMCD
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