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Neuropathologic basis of quantitative susceptibility mapping in the substantia nigra: contributions of tau, pigmented neurons, and iron.

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Title: Neuropathologic basis of quantitative susceptibility mapping in the substantia nigra: contributions of tau, pigmented neurons, and iron.
Authors: Ono D; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; Department of Neurology and Neurological Science, Institute of Science Tokyo, Tokyo, Japan.; School of Statistical Thinking, The Institute of Statistical Mathematics, Tokyo, Japan., Kondrakunta S; Department of Radiology, Opus Imaging Research Building, Mayo Clinic, Crossroads Dr SW, Rochester, MN, 55902, USA., Mak E; Department of Radiology, Opus Imaging Research Building, Mayo Clinic, Crossroads Dr SW, Rochester, MN, 55902, USA., Przybelski SA; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Fought AJ; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Schwarz CG; Department of Radiology, Opus Imaging Research Building, Mayo Clinic, Crossroads Dr SW, Rochester, MN, 55902, USA., Murray ME; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Nguyen A; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Reichard RR; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Senjem ML; Department of Radiology, Opus Imaging Research Building, Mayo Clinic, Crossroads Dr SW, Rochester, MN, 55902, USA.; Department of Information Technology, Mayo Clinic, Rochester, MN, USA., Gunter JL; Department of Radiology, Opus Imaging Research Building, Mayo Clinic, Crossroads Dr SW, Rochester, MN, 55902, USA., Jack CR Jr; Department of Radiology, Opus Imaging Research Building, Mayo Clinic, Crossroads Dr SW, Rochester, MN, 55902, USA., Miyagawa T; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Forsberg LK; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Fields JA; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA., Savica R; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Ramanan VK; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Jones DT; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Botha H; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Louis EKS; Department of Neurology, Mayo Clinic, Rochester, MN, USA.; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA.; Center for Sleep Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, MN, USA., Knopman DS; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Graff-Radford NR; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA., Day GS; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA., Ferman TJ; Department of Psychiatry and Psychology, Mayo Clinic, Jacksonville, FL, USA., Kremers WK; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Lowe VJ; Department of Radiology, Opus Imaging Research Building, Mayo Clinic, Crossroads Dr SW, Rochester, MN, 55902, USA., Petersen RC; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Boeve BF; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Dickson DW; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Kantarci K; Department of Radiology, Opus Imaging Research Building, Mayo Clinic, Crossroads Dr SW, Rochester, MN, 55902, USA. kantarci.kejal@mayo.edu.
Source: Acta neuropathologica [Acta Neuropathol] 2026 Feb 18; Vol. 151 (1), pp. 17. Date of Electronic Publication: 2026 Feb 18.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE
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  Data: Neuropathologic basis of quantitative susceptibility mapping in the substantia nigra: contributions of tau, pigmented neurons, and iron.
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  Data: <searchLink fieldCode="AU" term="%22Ono+D%22">Ono D</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; Department of Neurology and Neurological Science, Institute of Science Tokyo, Tokyo, Japan.; School of Statistical Thinking, The Institute of Statistical Mathematics, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kondrakunta+S%22">Kondrakunta S</searchLink>; Department of Radiology, Opus Imaging Research Building, Mayo Clinic, Crossroads Dr SW, Rochester, MN, 55902, USA.<br /><searchLink fieldCode="AU" term="%22Mak+E%22">Mak E</searchLink>; Department of Radiology, Opus Imaging Research Building, Mayo Clinic, Crossroads Dr SW, Rochester, MN, 55902, USA.<br /><searchLink fieldCode="AU" term="%22Przybelski+SA%22">Przybelski SA</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Fought+AJ%22">Fought AJ</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Schwarz+CG%22">Schwarz CG</searchLink>; Department of Radiology, Opus Imaging Research Building, Mayo Clinic, Crossroads Dr SW, Rochester, MN, 55902, USA.<br /><searchLink fieldCode="AU" term="%22Murray+ME%22">Murray ME</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+A%22">Nguyen A</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Reichard+RR%22">Reichard RR</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Senjem+ML%22">Senjem ML</searchLink>; Department of Radiology, Opus Imaging Research Building, Mayo Clinic, Crossroads Dr SW, Rochester, MN, 55902, USA.; Department of Information Technology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Gunter+JL%22">Gunter JL</searchLink>; Department of Radiology, Opus Imaging Research Building, Mayo Clinic, Crossroads Dr SW, Rochester, MN, 55902, USA.<br /><searchLink fieldCode="AU" term="%22Jack+CR+Jr%22">Jack CR Jr</searchLink>; Department of Radiology, Opus Imaging Research Building, Mayo Clinic, Crossroads Dr SW, Rochester, MN, 55902, USA.<br /><searchLink fieldCode="AU" term="%22Miyagawa+T%22">Miyagawa T</searchLink>; Department of Neurology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Forsberg+LK%22">Forsberg LK</searchLink>; Department of Neurology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Fields+JA%22">Fields JA</searchLink>; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Savica+R%22">Savica R</searchLink>; Department of Neurology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Ramanan+VK%22">Ramanan VK</searchLink>; Department of Neurology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Jones+DT%22">Jones DT</searchLink>; Department of Neurology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Botha+H%22">Botha H</searchLink>; Department of Neurology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Louis+EKS%22">Louis EKS</searchLink>; Department of Neurology, Mayo Clinic, Rochester, MN, USA.; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA.; Center for Sleep Medicine, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Knopman+DS%22">Knopman DS</searchLink>; Department of Neurology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Graff-Radford+NR%22">Graff-Radford NR</searchLink>; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Day+GS%22">Day GS</searchLink>; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Ferman+TJ%22">Ferman TJ</searchLink>; Department of Psychiatry and Psychology, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Kremers+WK%22">Kremers WK</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Lowe+VJ%22">Lowe VJ</searchLink>; Department of Radiology, Opus Imaging Research Building, Mayo Clinic, Crossroads Dr SW, Rochester, MN, 55902, USA.<br /><searchLink fieldCode="AU" term="%22Petersen+RC%22">Petersen RC</searchLink>; Department of Neurology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Boeve+BF%22">Boeve BF</searchLink>; Department of Neurology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Dickson+DW%22">Dickson DW</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Kantarci+K%22">Kantarci K</searchLink>; Department of Radiology, Opus Imaging Research Building, Mayo Clinic, Crossroads Dr SW, Rochester, MN, 55902, USA. kantarci.kejal@mayo.edu.
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  Data: <searchLink fieldCode="JN" term="%220412041%22">Acta neuropathologica</searchLink> [Acta Neuropathol] 2026 Feb 18; Vol. 151 (1), pp. 17. <i>Date of Electronic Publication: </i>2026 Feb 18.
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