T-Cell-Derived Exosomes From Multi Core Granules Exhibit Superior Caspase-3-Mediated Tumor-Suppressive Activity Compared to Those From Multivesicular Bodies.
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| Title: | T-Cell-Derived Exosomes From Multi Core Granules Exhibit Superior Caspase-3-Mediated Tumor-Suppressive Activity Compared to Those From Multivesicular Bodies. |
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| Authors: | Alawar N; Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), Saarland University, Homburg, Germany., Schirra C; Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), Saarland University, Homburg, Germany., Rasuli R; Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), Saarland University, Homburg, Germany.; Department of Medical Oncology and Hematology, University Hospital of Zürich (USZ), Zürich, Switzerland., Fecher-Trost C; Institute of Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany.; Department of Experimental and Clinical Toxicology and Pharmacology, Center for Molecular Signaling (PZMS), Saarland University, Homburg, Germany., Weins L; Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), Saarland University, Homburg, Germany.; Department of Hematology and Oncology, Caritas Klinikum Saarbrücken, Saarbrücken, Germany., Meyer MR; Department of Experimental and Clinical Toxicology and Pharmacology, Center for Molecular Signaling (PZMS), Saarland University, Homburg, Germany., Flockerzi V; Institute of Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany., Keller A; Clinical Bioinformatics, Saarland University, Saarbrücken, Germany.; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research, Saarbrücken, Germany.; PharmaScienceHub, Saarbrücken, Germany., Dustin ML; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK., Rettig J; Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), Saarland University, Homburg, Germany., Becherer U; Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), Saarland University, Homburg, Germany. |
| Source: | Journal of extracellular vesicles [J Extracell Vesicles] 2026 Feb; Vol. 15 (2), pp. e70239. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 101610479 Publication Model: Print Cited Medium: Internet ISSN: 2001-3078 (Electronic) Linking ISSN: 20013078 NLM ISO Abbreviation: J Extracell Vesicles Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41711633 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: T-Cell-Derived Exosomes From Multi Core Granules Exhibit Superior Caspase-3-Mediated Tumor-Suppressive Activity Compared to Those From Multivesicular Bodies. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Alawar+N%22">Alawar N</searchLink>; Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), Saarland University, Homburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schirra+C%22">Schirra C</searchLink>; Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), Saarland University, Homburg, Germany.<br /><searchLink fieldCode="AU" term="%22Rasuli+R%22">Rasuli R</searchLink>; Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), Saarland University, Homburg, Germany.; Department of Medical Oncology and Hematology, University Hospital of Zürich (USZ), Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Fecher-Trost+C%22">Fecher-Trost C</searchLink>; Institute of Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany.; Department of Experimental and Clinical Toxicology and Pharmacology, Center for Molecular Signaling (PZMS), Saarland University, Homburg, Germany.<br /><searchLink fieldCode="AU" term="%22Weins+L%22">Weins L</searchLink>; Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), Saarland University, Homburg, Germany.; Department of Hematology and Oncology, Caritas Klinikum Saarbrücken, Saarbrücken, Germany.<br /><searchLink fieldCode="AU" term="%22Meyer+MR%22">Meyer MR</searchLink>; Department of Experimental and Clinical Toxicology and Pharmacology, Center for Molecular Signaling (PZMS), Saarland University, Homburg, Germany.<br /><searchLink fieldCode="AU" term="%22Flockerzi+V%22">Flockerzi V</searchLink>; Institute of Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany.<br /><searchLink fieldCode="AU" term="%22Keller+A%22">Keller A</searchLink>; Clinical Bioinformatics, Saarland University, Saarbrücken, Germany.; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research, Saarbrücken, Germany.; PharmaScienceHub, Saarbrücken, Germany.<br /><searchLink fieldCode="AU" term="%22Dustin+ML%22">Dustin ML</searchLink>; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Rettig+J%22">Rettig J</searchLink>; Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), Saarland University, Homburg, Germany.<br /><searchLink fieldCode="AU" term="%22Becherer+U%22">Becherer U</searchLink>; Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), Saarland University, Homburg, Germany. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101610479%22">Journal of extracellular vesicles</searchLink> [J Extracell Vesicles] 2026 Feb; Vol. 15 (2), pp. e70239. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101610479 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2001-3078 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220013078%22">20013078 </searchLink><i>NLM ISO Abbreviation: </i>J Extracell Vesicles <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41711633 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/jev2.70239 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e70239 Titles: – TitleFull: T-Cell-Derived Exosomes From Multi Core Granules Exhibit Superior Caspase-3-Mediated Tumor-Suppressive Activity Compared to Those From Multivesicular Bodies. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Alawar N – PersonEntity: Name: NameFull: Schirra C – PersonEntity: Name: NameFull: Rasuli R – PersonEntity: Name: NameFull: Fecher-Trost C – PersonEntity: Name: NameFull: Weins L – PersonEntity: Name: NameFull: Meyer MR – PersonEntity: Name: NameFull: Flockerzi V – PersonEntity: Name: NameFull: Keller A – PersonEntity: Name: NameFull: Dustin ML – PersonEntity: Name: NameFull: Rettig J – PersonEntity: Name: NameFull: Becherer U IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: 2026 Feb Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2001-3078 Numbering: – Type: volume Value: 15 – Type: issue Value: 2 Titles: – TitleFull: Journal of extracellular vesicles Type: main |
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