Enhancing IgG fragment crystallizable sialylation improves the therapeutic activity of IL-23 cytokine blockade.

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Bibliographic Details
Title: Enhancing IgG fragment crystallizable sialylation improves the therapeutic activity of IL-23 cytokine blockade.
Authors: Kämpf S; Division of Genetics, Department of Biology, Friedrich Alexander University Erlangen-Nürnberg, Germany., Hematianlarki M; Division of Genetics, Department of Biology, Friedrich Alexander University Erlangen-Nürnberg, Germany., Altmann L; Division of Genetics, Department of Biology, Friedrich Alexander University Erlangen-Nürnberg, Germany., Bright JM; Nuvig Therapeutics Inc., Palo Alto, California, USA., Toda AM; Nuvig Therapeutics Inc., Palo Alto, California, USA., Mirzapoor Z; Division of Genetics, Department of Biology, Friedrich Alexander University Erlangen-Nürnberg, Germany., Zollner V; Division of Genetics, Department of Biology, Friedrich Alexander University Erlangen-Nürnberg, Germany., Werner A; Division of Genetics, Department of Biology, Friedrich Alexander University Erlangen-Nürnberg, Germany., Bulang J; Division of Genetics, Department of Biology, Friedrich Alexander University Erlangen-Nürnberg, Germany., Radovani B; Division of Genetics, Department of Biology, Friedrich Alexander University Erlangen-Nürnberg, Germany., Wöhner M; Division of Genetics, Department of Biology, Friedrich Alexander University Erlangen-Nürnberg, Germany., Avery W; Nuvig Therapeutics Inc., Palo Alto, California, USA., Karbarz MJ; Nuvig Therapeutics Inc., Palo Alto, California, USA., Conley PB; Nuvig Therapeutics Inc., Palo Alto, California, USA., Coffey GP; Nuvig Therapeutics Inc., Palo Alto, California, USA., Nimmerjahn F; Division of Genetics, Department of Biology, Friedrich Alexander University Erlangen-Nürnberg, Germany.
Source: JCI insight [JCI Insight] 2026 Feb 19; Vol. 11 (7). Date of Electronic Publication: 2026 Feb 19 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2379-3708
DOI:10.1172/jci.insight.198630