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Imidazole as a Pendant Reactivation Ligand Increases Efficacy Scope for Reactivation and Resurrection of Organophosphorus-Inhibited/Aged Cholinesterases by Quinone Methide Precursors.

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Title: Imidazole as a Pendant Reactivation Ligand Increases Efficacy Scope for Reactivation and Resurrection of Organophosphorus-Inhibited/Aged Cholinesterases by Quinone Methide Precursors.
Authors: Lovins AR; Department of Chemistry and Biochemistry, Ohio State University, Columbus, Ohio 43210, United States., Miller KA; Department of Chemistry and Biochemistry, Ohio State University, Columbus, Ohio 43210, United States., Homoelle RK; Department of Chemistry and Biochemistry, Ohio State University, Columbus, Ohio 43210, United States., Hoover HJ; Department of Chemistry and Biochemistry, Ohio State University, Columbus, Ohio 43210, United States., McElroy CA; InfinixBio, 1507 Chambers Road, Columbus, Ohio 43212, United States., Callam CS; Department of Chemistry and Biochemistry, Ohio State University, Columbus, Ohio 43210, United States., Hadad CM; Department of Chemistry and Biochemistry, Ohio State University, Columbus, Ohio 43210, United States.
Source: ACS chemical neuroscience [ACS Chem Neurosci] 2026 Mar 04; Vol. 17 (5), pp. 962-975. Date of Electronic Publication: 2026 Feb 19.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="JN" term="%22101525337%22">ACS chemical neuroscience</searchLink> [ACS Chem Neurosci] 2026 Mar 04; Vol. 17 (5), pp. 962-975. <i>Date of Electronic Publication: </i>2026 Feb 19.
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        Value: 10.1021/acschemneuro.5c00631
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              Text: 2026 Mar 04
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