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Development and validation of a robust UPLC-MS/MS method for the analysis of polyamines in cells, biofluids and tissues.

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Bibliographic Details
Title: Development and validation of a robust UPLC-MS/MS method for the analysis of polyamines in cells, biofluids and tissues.
Authors: Iannone M; Neuroscience Discovery, Johnson&Johnson, Beerse, Belgium., Vereyken L; Preclinical Sciences & Translational Safety, Johnson&Johnson, Beerse, Belgium., Grajchen E; Neuroscience Discovery, Johnson&Johnson, Beerse, Belgium., Deneubourg C; Neuroscience Discovery, Johnson&Johnson, Beerse, Belgium., Gorremans S; Neuroscience Discovery, Johnson&Johnson, Beerse, Belgium., Donck LV; Neuroscience Discovery, Johnson&Johnson, Beerse, Belgium., Bretteville A; Neuroscience Discovery, Johnson&Johnson, Beerse, Belgium., Moechars D; Neuroscience Discovery, Johnson&Johnson, Beerse, Belgium., Jahouh F; Preclinical Sciences & Translational Safety, Johnson&Johnson, Beerse, Belgium. Electronic address: fjahouh@its.jnj.com., Vreeken RJ; Maastricht MultiModal Molecular Imaging Institute (M4I), Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, the Netherlands.
Source: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2026 Jul 15; Vol. 274, pp. 117392. Date of Electronic Publication: 2026 Feb 13.
Publication Type: Journal Article; Validation Study
Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-264X
DOI:10.1016/j.jpba.2026.117392