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Liver exerkine reverses aging- and Alzheimer's-related memory loss via vasculature.

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Title: Liver exerkine reverses aging- and Alzheimer's-related memory loss via vasculature.
Authors: Bieri G; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: gregbieri@gmail.com., Pratt KJB; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA., Fuseya Y; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA., Aghayev T; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA., Sucharov J; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA., Horowitz AM; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA., Philp AR; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA., Fonseca-Valencia K; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA; Pharmaceutical Sciences and Pharmacogenomics Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA., Chu R; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA., Phan M; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA., Remesal L; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA., Wang SJ; Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA; Department of Neurology, Duke University Medical Center, Durham, NC 27710, USA., Yang AC; Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA., Casaletto KB; Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA; Memory and Aging Center, Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA., Villeda SA; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA; Pharmaceutical Sciences and Pharmacogenomics Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Physical Therapy and Rehabilitation Science, University of California, San Francisco, San Francisco, CA 94143, USA; Bakar Aging Research Institute, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: saul.villeda@ucsf.edu.
Source: Cell [Cell] 2026 Mar 05; Vol. 189 (5), pp. 1499-1516.e25. Date of Electronic Publication: 2026 Feb 18.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Liver exerkine reverses aging- and Alzheimer's-related memory loss via vasculature.
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  Data: <searchLink fieldCode="AU" term="%22Bieri+G%22">Bieri G</searchLink>; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: gregbieri@gmail.com.<br /><searchLink fieldCode="AU" term="%22Pratt+KJB%22">Pratt KJB</searchLink>; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Fuseya+Y%22">Fuseya Y</searchLink>; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Aghayev+T%22">Aghayev T</searchLink>; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Sucharov+J%22">Sucharov J</searchLink>; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Horowitz+AM%22">Horowitz AM</searchLink>; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Philp+AR%22">Philp AR</searchLink>; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Fonseca-Valencia+K%22">Fonseca-Valencia K</searchLink>; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA; Pharmaceutical Sciences and Pharmacogenomics Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Chu+R%22">Chu R</searchLink>; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Phan+M%22">Phan M</searchLink>; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Remesal+L%22">Remesal L</searchLink>; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Wang+SJ%22">Wang SJ</searchLink>; Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA; Department of Neurology, Duke University Medical Center, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Yang+AC%22">Yang AC</searchLink>; Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Casaletto+KB%22">Casaletto KB</searchLink>; Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA; Memory and Aging Center, Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Villeda+SA%22">Villeda SA</searchLink>; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA; Pharmaceutical Sciences and Pharmacogenomics Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Physical Therapy and Rehabilitation Science, University of California, San Francisco, San Francisco, CA 94143, USA; Bakar Aging Research Institute, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: saul.villeda@ucsf.edu.
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  Data: <searchLink fieldCode="JN" term="%220413066%22">Cell</searchLink> [Cell] 2026 Mar 05; Vol. 189 (5), pp. 1499-1516.e25. <i>Date of Electronic Publication: </i>2026 Feb 18.
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