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The impact of acute normovolemic hemodilution on blood transfusions in cardiac surgery: a GRADE-assessed systematic review and meta-analysis of 30 randomized controlled trials with trial sequential analysis.

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Title: The impact of acute normovolemic hemodilution on blood transfusions in cardiac surgery: a GRADE-assessed systematic review and meta-analysis of 30 randomized controlled trials with trial sequential analysis.
Authors: Alam U; Khyber Medical College, Peshawar, Pakistan., Rath S; All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, India. Shreerath4a@gmail.com., Ansab M; Services Institute of Medical Sciences, Lahore, Pakistan., Khattak F; Khyber Medical College, Peshawar, Pakistan., Siddiqui HT; Jinnah Sindh Medical University, Karachi, Pakistan., Burhan M; Dow University of Health Sciences, Karachi, Sindh, Pakistan., Moiz A; Bacha Khan Medical College, Mardan, Pakistan., Sabir V; Khyber Medical College, Peshawar, Pakistan., Afridi ZAK; Khyber Medical College, Peshawar, Pakistan.
Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2026 May; Vol. 399 (8), pp. 11035-11054. Date of Electronic Publication: 2026 Feb 20.
Publication Type: Journal Article; Systematic Review; Meta-Analysis; Review
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The impact of acute normovolemic hemodilution on blood transfusions in cardiac surgery: a GRADE-assessed systematic review and meta-analysis of 30 randomized controlled trials with trial sequential analysis.
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  Data: <searchLink fieldCode="AU" term="%22Alam+U%22">Alam U</searchLink>; Khyber Medical College, Peshawar, Pakistan.<br /><searchLink fieldCode="AU" term="%22Rath+S%22">Rath S</searchLink>; All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, India. Shreerath4a@gmail.com.<br /><searchLink fieldCode="AU" term="%22Ansab+M%22">Ansab M</searchLink>; Services Institute of Medical Sciences, Lahore, Pakistan.<br /><searchLink fieldCode="AU" term="%22Khattak+F%22">Khattak F</searchLink>; Khyber Medical College, Peshawar, Pakistan.<br /><searchLink fieldCode="AU" term="%22Siddiqui+HT%22">Siddiqui HT</searchLink>; Jinnah Sindh Medical University, Karachi, Pakistan.<br /><searchLink fieldCode="AU" term="%22Burhan+M%22">Burhan M</searchLink>; Dow University of Health Sciences, Karachi, Sindh, Pakistan.<br /><searchLink fieldCode="AU" term="%22Moiz+A%22">Moiz A</searchLink>; Bacha Khan Medical College, Mardan, Pakistan.<br /><searchLink fieldCode="AU" term="%22Sabir+V%22">Sabir V</searchLink>; Khyber Medical College, Peshawar, Pakistan.<br /><searchLink fieldCode="AU" term="%22Afridi+ZAK%22">Afridi ZAK</searchLink>; Khyber Medical College, Peshawar, Pakistan.
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  Data: <searchLink fieldCode="JN" term="%220326264%22">Naunyn-Schmiedeberg's archives of pharmacology</searchLink> [Naunyn Schmiedebergs Arch Pharmacol] 2026 May; Vol. 399 (8), pp. 11035-11054. <i>Date of Electronic Publication: </i>2026 Feb 20.
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        Value: 10.1007/s00210-026-05051-z
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      – Code: eng
        Text: English
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        StartPage: 11035
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      – TitleFull: The impact of acute normovolemic hemodilution on blood transfusions in cardiac surgery: a GRADE-assessed systematic review and meta-analysis of 30 randomized controlled trials with trial sequential analysis.
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              M: 05
              Text: 2026 May
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              Y: 2026
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