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Pharmacogenomics of antiepileptic drug mood stabilizer treatment response in bipolar disorder: A MoStGen Consortium study.

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Title: Pharmacogenomics of antiepileptic drug mood stabilizer treatment response in bipolar disorder: A MoStGen Consortium study.
Authors: Ho AM; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA., Coombes BJ; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Batzler A; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Pazdernik VK; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Pendegraft RS; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Skime M; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA., Bendjemaa N; GHU Paris Psychiatrie et Neurosciences, Hôpital Sainte Anne, Paris, France., Carpiniello B; Section of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.; Unit of Clinical Psychiatry, University Hospital Agency of Cagliari, Cagliari, Italy., Contu M; Section of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy., Dalkner N; Division of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, Graz, Austria., Fellendorf FT; Division of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, Graz, Austria., Fico G; Institute of Neuroscience, University of Barcelona, Barcelona, Catalonia, Spain.; Hospital Clinic, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain., Fullerton CD; Department of Psychiatry, Faculty of Medicine, Universidad de los Andes, Santiago, Chile.; Mental Health Service, Clínica Universidad de los Andes, Santiago, Chile., Gardea-Resendez M; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA.; Department of Psychiatry, School of Medicine, Universidad Autonoma de Nuevo Leon, Monterrey, Mexico., Gonzalez-Garza S; Department of Psychiatry, School of Medicine, Universidad Autonoma de Nuevo Leon, Monterrey, Mexico., Jaafari N; Unité de Recherche Clinique Intersectorielle en Psychiatrie, Centre Hospitalier Henri Laborit, Poitiers, France., Jiménez E; Institute of Neuroscience, University of Barcelona, Barcelona, Catalonia, Spain.; Hospital Clinic, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain.; Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM-ISCIII, Madrid, Spain., Kebir O; GHU Paris Psychiatrie et Neurosciences, Hôpital Sainte Anne, Paris, France.; Université Paris Cité, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM U1266, Paris, France., Legrand A; GHU Paris Psychiatrie et Neurosciences, Hôpital Sainte Anne, Paris, France.; Université Paris Cité, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM U1266, Paris, France., Luna-Garza S; Department of Psychiatry, School of Medicine, Universidad Autonoma de Nuevo Leon, Monterrey, Mexico., Meloni A; Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy., Millet B; Infrastructure of Clinical Research in Neurosciences-Psychiatry, Brain Institute (ICM), Sorbonne Université, INSERM, Paris, France.; Service de Psychiatrie Adulte de la Pitié-Salpêtrière, Sorbonne Université, Paris, France., Mouaffak F; Université Paris Cité, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM U1266, Paris, France.; EPS Ville Evrard, Saint Denis, France., Nunes A; Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada., O'Donovan C; Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada., Paribello P; Section of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.; Unit of Clinical Psychiatry, University Hospital Agency of Cagliari, Cagliari, Italy., Pinna M; Section of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy., Pisanu C; Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy., Pomarol-Clotet E; FIDMAG Germanes Hospitalàries Research Foundation, Barcelona, Spain.; Centro de Investigacion Biomedica en Red de Salud Mental, CIBERSAM-ISCIII, Barcelona, Spain., Romo-Nava F; Lindner Center of HOPE, Mason, OH, USA.; Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Sánchez RF; Mood and Anxiety Clinical Center, Santiago, Chile., Scott K; Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada., Squassina A; Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy.; Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada., Vilella E; Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM-ISCIII, Madrid, Spain.; Institut d'Investigació Sanitària Pere Virgili-CERCA, Reus, Spain.; Universitat Rovira i Virgili, Tarragona, Spain.; Hospital Universitari Institut Pere Mata, Reus, Spain., Serretti A; Department of Medicine and Surgery, Kore University of Enna, Enna, Italy.; Oasi Research Institute-IRCCS, Troina, Italy., Prieto ML; Department of Psychiatry, Faculty of Medicine, Universidad de los Andes, Santiago, Chile.; Mental Health Service, Clínica Universidad de los Andes, Santiago, Chile., Reininghaus EZ; Division of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, Graz, Austria., Bengesser SA; Division of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, Graz, Austria., Cuellar-Barboza AB; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA.; Department of Psychiatry, School of Medicine, Universidad Autonoma de Nuevo Leon, Monterrey, Mexico., Krebs MO; GHU Paris Psychiatrie et Neurosciences, Hôpital Sainte Anne, Paris, France.; Université Paris Cité, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM U1266, Paris, France., Chaumette B; GHU Paris Psychiatrie et Neurosciences, Hôpital Sainte Anne, Paris, France.; Université Paris Cité, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM U1266, Paris, France.; Department of Psychiatry, McGill University, Montreal, Canada., Vieta E; Institute of Neuroscience, University of Barcelona, Barcelona, Catalonia, Spain.; Hospital Clinic, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain., Manchia M; Section of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.; Unit of Clinical Psychiatry, University Hospital Agency of Cagliari, Cagliari, Italy.; Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada., McElroy SL; Lindner Center of HOPE, Mason, OH, USA.; Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Alda M; Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.; National Institute of Mental Health, Klecany, Czech Republic., Frye MA; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA., Biernacka JM; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA. Biernacka.Joanna@mayo.edu.; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA. Biernacka.Joanna@mayo.edu.
Source: Molecular psychiatry [Mol Psychiatry] 2026 Jun; Vol. 31 (6), pp. 3587-3594. Date of Electronic Publication: 2026 Feb 19.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pharmacogenomics of antiepileptic drug mood stabilizer treatment response in bipolar disorder: A MoStGen Consortium study.
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  Data: <searchLink fieldCode="AU" term="%22Ho+AM%22">Ho AM</searchLink>; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Coombes+BJ%22">Coombes BJ</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Batzler+A%22">Batzler A</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Pazdernik+VK%22">Pazdernik VK</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Pendegraft+RS%22">Pendegraft RS</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Skime+M%22">Skime M</searchLink>; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Bendjemaa+N%22">Bendjemaa N</searchLink>; GHU Paris Psychiatrie et Neurosciences, Hôpital Sainte Anne, Paris, France.<br /><searchLink fieldCode="AU" term="%22Carpiniello+B%22">Carpiniello B</searchLink>; Section of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.; Unit of Clinical Psychiatry, University Hospital Agency of Cagliari, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Contu+M%22">Contu M</searchLink>; Section of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Dalkner+N%22">Dalkner N</searchLink>; Division of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Fellendorf+FT%22">Fellendorf FT</searchLink>; Division of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Fico+G%22">Fico G</searchLink>; Institute of Neuroscience, University of Barcelona, Barcelona, Catalonia, Spain.; 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Institute of Neuroscience, University of Barcelona, Barcelona, Catalonia, Spain.; Hospital Clinic, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain.; Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM-ISCIII, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Kebir+O%22">Kebir O</searchLink>; GHU Paris Psychiatrie et Neurosciences, Hôpital Sainte Anne, Paris, France.; Université Paris Cité, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM U1266, Paris, France.<br /><searchLink fieldCode="AU" term="%22Legrand+A%22">Legrand A</searchLink>; GHU Paris Psychiatrie et Neurosciences, Hôpital Sainte Anne, Paris, France.; Université Paris Cité, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM U1266, Paris, France.<br /><searchLink fieldCode="AU" term="%22Luna-Garza+S%22">Luna-Garza S</searchLink>; Department of Psychiatry, School of Medicine, Universidad Autonoma de Nuevo Leon, Monterrey, Mexico.<br /><searchLink fieldCode="AU" term="%22Meloni+A%22">Meloni A</searchLink>; 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Department of Psychiatry, Faculty of Medicine, Universidad de los Andes, Santiago, Chile.; Mental Health Service, Clínica Universidad de los Andes, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Reininghaus+EZ%22">Reininghaus EZ</searchLink>; Division of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Bengesser+SA%22">Bengesser SA</searchLink>; Division of Psychiatry and Psychotherapeutic Medicine, Medical University Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Cuellar-Barboza+AB%22">Cuellar-Barboza AB</searchLink>; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA.; Department of Psychiatry, School of Medicine, Universidad Autonoma de Nuevo Leon, Monterrey, Mexico.<br /><searchLink fieldCode="AU" term="%22Krebs+MO%22">Krebs MO</searchLink>; GHU Paris Psychiatrie et Neurosciences, Hôpital Sainte Anne, Paris, France.; Université Paris Cité, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM U1266, Paris, France.<br /><searchLink fieldCode="AU" term="%22Chaumette+B%22">Chaumette B</searchLink>; GHU Paris Psychiatrie et Neurosciences, Hôpital Sainte Anne, Paris, France.; Université Paris Cité, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM U1266, Paris, France.; Department of Psychiatry, McGill University, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Vieta+E%22">Vieta E</searchLink>; Institute of Neuroscience, University of Barcelona, Barcelona, Catalonia, Spain.; Hospital Clinic, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain.<br /><searchLink fieldCode="AU" term="%22Manchia+M%22">Manchia M</searchLink>; Section of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.; Unit of Clinical Psychiatry, University Hospital Agency of Cagliari, Cagliari, Italy.; Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada.<br /><searchLink fieldCode="AU" term="%22McElroy+SL%22">McElroy SL</searchLink>; Lindner Center of HOPE, Mason, OH, USA.; Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Alda+M%22">Alda M</searchLink>; Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.; National Institute of Mental Health, Klecany, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Frye+MA%22">Frye MA</searchLink>; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Biernacka+JM%22">Biernacka JM</searchLink>; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA. Biernacka.Joanna@mayo.edu.; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA. Biernacka.Joanna@mayo.edu.
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            NameFull: Frye MA
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          Name:
            NameFull: Biernacka JM
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 06
              Text: 2026 Jun
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1476-5578
          Numbering:
            – Type: volume
              Value: 31
            – Type: issue
              Value: 6
          Titles:
            – TitleFull: Molecular psychiatry
              Type: main
ResultId 1