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Mitochondrial bioenergetics-SASP crosstalk determines senolytic efficacy in therapy-induced senescence.

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Title: Mitochondrial bioenergetics-SASP crosstalk determines senolytic efficacy in therapy-induced senescence.
Authors: Llop-Hernández À; Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology, Girona, Spain.; Metabolism and Cancer Group, Girona Biomedical Research Institute (IDIBGI), Girona, Spain., Verdura S; Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology, Girona, Spain.; Metabolism and Cancer Group, Girona Biomedical Research Institute (IDIBGI), Girona, Spain., López J; Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology, Girona, Spain.; Metabolism and Cancer Group, Girona Biomedical Research Institute (IDIBGI), Girona, Spain.; Biochemistry and Molecular Biology Unit, Department of Biology, University of Girona, Girona, Spain., Martin-Castillo B; Metabolism and Cancer Group, Girona Biomedical Research Institute (IDIBGI), Girona, Spain.; Unit of Clinical Research, Catalan Institute of Oncology, Girona, Spain., Menendez JA; Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology, Girona, Spain. jmenendez@idibgi.org.; Metabolism and Cancer Group, Girona Biomedical Research Institute (IDIBGI), Girona, Spain. jmenendez@idibgi.org., Cuyàs E; Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology, Girona, Spain. ecuyas@idibgi.org.; Metabolism and Cancer Group, Girona Biomedical Research Institute (IDIBGI), Girona, Spain. ecuyas@idibgi.org.
Source: Cell death discovery [Cell Death Discov] 2026 Feb 19; Vol. 12 (1). Date of Electronic Publication: 2026 Feb 19.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Mitochondrial bioenergetics-SASP crosstalk determines senolytic efficacy in therapy-induced senescence.
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  Data: <searchLink fieldCode="AU" term="%22Llop-Hernández+À%22">Llop-Hernández À</searchLink>; Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology, Girona, Spain.; Metabolism and Cancer Group, Girona Biomedical Research Institute (IDIBGI), Girona, Spain.<br /><searchLink fieldCode="AU" term="%22Verdura+S%22">Verdura S</searchLink>; Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology, Girona, Spain.; Metabolism and Cancer Group, Girona Biomedical Research Institute (IDIBGI), Girona, Spain.<br /><searchLink fieldCode="AU" term="%22López+J%22">López J</searchLink>; Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology, Girona, Spain.; Metabolism and Cancer Group, Girona Biomedical Research Institute (IDIBGI), Girona, Spain.; Biochemistry and Molecular Biology Unit, Department of Biology, University of Girona, Girona, Spain.<br /><searchLink fieldCode="AU" term="%22Martin-Castillo+B%22">Martin-Castillo B</searchLink>; Metabolism and Cancer Group, Girona Biomedical Research Institute (IDIBGI), Girona, Spain.; Unit of Clinical Research, Catalan Institute of Oncology, Girona, Spain.<br /><searchLink fieldCode="AU" term="%22Menendez+JA%22">Menendez JA</searchLink>; Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology, Girona, Spain. jmenendez@idibgi.org.; Metabolism and Cancer Group, Girona Biomedical Research Institute (IDIBGI), Girona, Spain. jmenendez@idibgi.org.<br /><searchLink fieldCode="AU" term="%22Cuyàs+E%22">Cuyàs E</searchLink>; Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology, Girona, Spain. ecuyas@idibgi.org.; Metabolism and Cancer Group, Girona Biomedical Research Institute (IDIBGI), Girona, Spain. ecuyas@idibgi.org.
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  Data: <searchLink fieldCode="JN" term="%22101665035%22">Cell death discovery</searchLink> [Cell Death Discov] 2026 Feb 19; Vol. 12 (1). <i>Date of Electronic Publication: </i>2026 Feb 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101665035 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2058-7716 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220587716%22">20587716 </searchLink><i>NLM ISO Abbreviation: </i>Cell Death Discov <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1038/s41420-026-02967-6
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              Text: 2026 Feb 19
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