View in EDS

Variation in guide RNA library representation results in gene effect score bias in genome-wide CRISPR screens.

Saved in:
Bibliographic Details
Title: Variation in guide RNA library representation results in gene effect score bias in genome-wide CRISPR screens.
Authors: Metz P; Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK.; Department of Neurosurgery, Erasmus University Medical Centre, Rotterdam, The Netherlands., Alves-Vasconcelos S; Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK., Wallbank R; Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK., Riepsaame J; Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK.; Genome Engineering Oxford, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK., Brown S; Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK., Hassan AB; Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK. bass.hassan@path.ox.ac.uk.
Source: BMC genomics [BMC Genomics] 2026 Feb 20; Vol. 27 (1). Date of Electronic Publication: 2026 Feb 20.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164 (Electronic) Linking ISSN: 14712164 NLM ISO Abbreviation: BMC Genomics Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41715004
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Variation in guide RNA library representation results in gene effect score bias in genome-wide CRISPR screens.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Metz+P%22">Metz P</searchLink>; Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK.; Department of Neurosurgery, Erasmus University Medical Centre, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Alves-Vasconcelos+S%22">Alves-Vasconcelos S</searchLink>; Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK.<br /><searchLink fieldCode="AU" term="%22Wallbank+R%22">Wallbank R</searchLink>; Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK.<br /><searchLink fieldCode="AU" term="%22Riepsaame+J%22">Riepsaame J</searchLink>; Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK.; Genome Engineering Oxford, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK.<br /><searchLink fieldCode="AU" term="%22Brown+S%22">Brown S</searchLink>; Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK.<br /><searchLink fieldCode="AU" term="%22Hassan+AB%22">Hassan AB</searchLink>; Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK. bass.hassan@path.ox.ac.uk.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22100965258%22">BMC genomics</searchLink> [BMC Genomics] 2026 Feb 20; Vol. 27 (1). <i>Date of Electronic Publication: </i>2026 Feb 20.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100965258 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1471-2164 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214712164%22">14712164 </searchLink><i>NLM ISO Abbreviation: </i>BMC Genomics <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41715004
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1186/s12864-026-12658-2
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Variation in guide RNA library representation results in gene effect score bias in genome-wide CRISPR screens.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Metz P
      – PersonEntity:
          Name:
            NameFull: Alves-Vasconcelos S
      – PersonEntity:
          Name:
            NameFull: Wallbank R
      – PersonEntity:
          Name:
            NameFull: Riepsaame J
      – PersonEntity:
          Name:
            NameFull: Brown S
      – PersonEntity:
          Name:
            NameFull: Hassan AB
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 20
              M: 02
              Text: 2026 Feb 20
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1471-2164
          Numbering:
            – Type: volume
              Value: 27
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: BMC genomics
              Type: main
ResultId 1