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Spironolactone and Fibrosis in Heart Failure Risk: Machine Learning Analysis of HOMAGE Trial Plasma Proteomics.

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Title: Spironolactone and Fibrosis in Heart Failure Risk: Machine Learning Analysis of HOMAGE Trial Plasma Proteomics.
Authors: Ravassa S; Laboratory of Heart Failure CIMA Universidad de Navarra and IdiSNA Pamplona Spain.; CIBERCV, Carlos III Institute of Health Madrid Spain., Girerd N; Inserm, Centre d'Investigation Clinique Plurithématique 1433, U1116, CHRU De Nancy, F-CRIN INI-CRCT Université De Lorraine Nancy France., Edelman F; Department of Internal Medicine and Cardiology Campus Virchow Klinikum Charité University Medicine Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Berlin Berlin Germany., López B; Laboratory of Heart Failure CIMA Universidad de Navarra and IdiSNA Pamplona Spain.; CIBERCV, Carlos III Institute of Health Madrid Spain., Ferreira JP; Inserm, Centre d'Investigation Clinique Plurithématique 1433, U1116, CHRU De Nancy, F-CRIN INI-CRCT Université De Lorraine Nancy France.; Cardiovascular Research and Development Center, Department of Surgery and Physiology Faculty of Medicine of the University of Porto Porto Portugal., Zurkan D; Department of Internal Medicine and Cardiology Campus Virchow Klinikum Charité University Medicine Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Berlin Berlin Germany., José GS; Laboratory of Heart Failure CIMA Universidad de Navarra and IdiSNA Pamplona Spain.; CIBERCV, Carlos III Institute of Health Madrid Spain., Latasa I; Laboratory of Heart Failure CIMA Universidad de Navarra and IdiSNA Pamplona Spain.; CIBERCV, Carlos III Institute of Health Madrid Spain., Pellicori P; School of Cardiovascular and Metabolic Health University of Glasgow Glasgow UK., Cosmi F; Department of Cardiology Cortona Hospital Arezzo Italy., Petutschnigg J; DZHK (German Centre for Cardiovascular Research), Partner Site Berlin Berlin Germany.; Deutsches Herzzentrum der Charité, Klinik für Kardiologie Angiologie & Intensivmedizin, Augustenburger Platz 1 Berlin Germany.; Charité - Universitätsmedizin Berlin Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin Berlin Germany., Heymans S; Department of Cardiology Maastricht University Medical Center Maastricht the Netherlands., Brunner-La Rocca HP; Department of Cardiology Maastricht University Medical Center Maastricht the Netherlands., Pieske B; Division of Cardiology, Department of Internal Medicine University Medicine Rostock Rostock Germany., Delles C; School of Cardiovascular and Metabolic Health University of Glasgow Glasgow UK., Clark AL; Castle Hill Hospital Hull University Teaching Hospitals NHS Trust Cottingham UK., Díez J; Laboratory of Heart Failure CIMA Universidad de Navarra and IdiSNA Pamplona Spain.; CIBERCV, Carlos III Institute of Health Madrid Spain., Zannad F; Inserm, Centre d'Investigation Clinique Plurithématique 1433, U1116, CHRU De Nancy, F-CRIN INI-CRCT Université De Lorraine Nancy France., Cleland JGF; School of Cardiovascular and Metabolic Health University of Glasgow Glasgow UK., González A; Laboratory of Heart Failure CIMA Universidad de Navarra and IdiSNA Pamplona Spain.; CIBERCV, Carlos III Institute of Health Madrid Spain.; Department of Cardiology and Cardiac Surgery Clínica Universidad de Navarra Pamplona Spain.
Corporate Authors: HOMAGE Trial Committees and Investigators
Source: MedComm [MedComm (2020)] 2026 Feb 17; Vol. 7 (3), pp. e70634. Date of Electronic Publication: 2026 Feb 17 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: China NLM ID: 101769925 Publication Model: eCollection Cited Medium: Internet ISSN: 2688-2663 (Electronic) Linking ISSN: 26882663 NLM ISO Abbreviation: MedComm (2020) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Spironolactone and Fibrosis in Heart Failure Risk: Machine Learning Analysis of HOMAGE Trial Plasma Proteomics.
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  Data: <searchLink fieldCode="AU" term="%22Ravassa+S%22">Ravassa S</searchLink>; Laboratory of Heart Failure CIMA Universidad de Navarra and IdiSNA Pamplona Spain.; CIBERCV, Carlos III Institute of Health Madrid Spain.<br /><searchLink fieldCode="AU" term="%22Girerd+N%22">Girerd N</searchLink>; Inserm, Centre d'Investigation Clinique Plurithématique 1433, U1116, CHRU De Nancy, F-CRIN INI-CRCT Université De Lorraine Nancy France.<br /><searchLink fieldCode="AU" term="%22Edelman+F%22">Edelman F</searchLink>; Department of Internal Medicine and Cardiology Campus Virchow Klinikum Charité University Medicine Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Berlin Berlin Germany.<br /><searchLink fieldCode="AU" term="%22López+B%22">López B</searchLink>; Laboratory of Heart Failure CIMA Universidad de Navarra and IdiSNA Pamplona Spain.; CIBERCV, Carlos III Institute of Health Madrid Spain.<br /><searchLink fieldCode="AU" term="%22Ferreira+JP%22">Ferreira JP</searchLink>; Inserm, Centre d'Investigation Clinique Plurithématique 1433, U1116, CHRU De Nancy, F-CRIN INI-CRCT Université De Lorraine Nancy France.; Cardiovascular Research and Development Center, Department of Surgery and Physiology Faculty of Medicine of the University of Porto Porto Portugal.<br /><searchLink fieldCode="AU" term="%22Zurkan+D%22">Zurkan D</searchLink>; Department of Internal Medicine and Cardiology Campus Virchow Klinikum Charité University Medicine Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Berlin Berlin Germany.<br /><searchLink fieldCode="AU" term="%22José+GS%22">José GS</searchLink>; Laboratory of Heart Failure CIMA Universidad de Navarra and IdiSNA Pamplona Spain.; CIBERCV, Carlos III Institute of Health Madrid Spain.<br /><searchLink fieldCode="AU" term="%22Latasa+I%22">Latasa I</searchLink>; Laboratory of Heart Failure CIMA Universidad de Navarra and IdiSNA Pamplona Spain.; CIBERCV, Carlos III Institute of Health Madrid Spain.<br /><searchLink fieldCode="AU" term="%22Pellicori+P%22">Pellicori P</searchLink>; School of Cardiovascular and Metabolic Health University of Glasgow Glasgow UK.<br /><searchLink fieldCode="AU" term="%22Cosmi+F%22">Cosmi F</searchLink>; Department of Cardiology Cortona Hospital Arezzo Italy.<br /><searchLink fieldCode="AU" term="%22Petutschnigg+J%22">Petutschnigg J</searchLink>; DZHK (German Centre for Cardiovascular Research), Partner Site Berlin Berlin Germany.; Deutsches Herzzentrum der Charité, Klinik für Kardiologie Angiologie & Intensivmedizin, Augustenburger Platz 1 Berlin Germany.; Charité - Universitätsmedizin Berlin Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin Berlin Germany.<br /><searchLink fieldCode="AU" term="%22Heymans+S%22">Heymans S</searchLink>; Department of Cardiology Maastricht University Medical Center Maastricht the Netherlands.<br /><searchLink fieldCode="AU" term="%22Brunner-La+Rocca+HP%22">Brunner-La Rocca HP</searchLink>; Department of Cardiology Maastricht University Medical Center Maastricht the Netherlands.<br /><searchLink fieldCode="AU" term="%22Pieske+B%22">Pieske B</searchLink>; Division of Cardiology, Department of Internal Medicine University Medicine Rostock Rostock Germany.<br /><searchLink fieldCode="AU" term="%22Delles+C%22">Delles C</searchLink>; School of Cardiovascular and Metabolic Health University of Glasgow Glasgow UK.<br /><searchLink fieldCode="AU" term="%22Clark+AL%22">Clark AL</searchLink>; Castle Hill Hospital Hull University Teaching Hospitals NHS Trust Cottingham UK.<br /><searchLink fieldCode="AU" term="%22Díez+J%22">Díez J</searchLink>; Laboratory of Heart Failure CIMA Universidad de Navarra and IdiSNA Pamplona Spain.; CIBERCV, Carlos III Institute of Health Madrid Spain.<br /><searchLink fieldCode="AU" term="%22Zannad+F%22">Zannad F</searchLink>; Inserm, Centre d'Investigation Clinique Plurithématique 1433, U1116, CHRU De Nancy, F-CRIN INI-CRCT Université De Lorraine Nancy France.<br /><searchLink fieldCode="AU" term="%22Cleland+JGF%22">Cleland JGF</searchLink>; School of Cardiovascular and Metabolic Health University of Glasgow Glasgow UK.<br /><searchLink fieldCode="AU" term="%22González+A%22">González A</searchLink>; Laboratory of Heart Failure CIMA Universidad de Navarra and IdiSNA Pamplona Spain.; CIBERCV, Carlos III Institute of Health Madrid Spain.; Department of Cardiology and Cardiac Surgery Clínica Universidad de Navarra Pamplona Spain.
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