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A critical analysis of the IMWG multiple myeloma complete response criterion in the era of mass spectrometry.

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Title: A critical analysis of the IMWG multiple myeloma complete response criterion in the era of mass spectrometry.
Authors: Puig N; Hematology Department IBSAL, Instituto de Biología Molecular y Celular del Cáncer-Consejo Superior de Investigaciones Científicas (IBMCC-CSIC), Centro de Investigación Biomédica en Red de Cáncer (CIBERONC) Salamanca Spain., Agulló C; Clinical Biochemistry Department Hospital Universitario de Salamanca Salamanca Spain., Paiva B; Clínica Universidad de Navarra, CUN, CIMA, IDISNA, CIBERONC CB16/12/00369 Pamplona Spain., Cedena MT; Hospital Universitario 12 de Octubre, Complutense University, i + 12, CNIO, CIBERONC, CB16/12/00369 Madrid Spain., Rosiñol L; Hospital Clinic, Institut d'Investigacions Biomédiques August Pi I Sunyer (IDIBAPS) Barcelona Spain., Contreras T; Clinical Biochemistry Department Hospital Universitario de Salamanca Salamanca Spain., Martínez-López J; Hospital Universitario 12 de Octubre, Complutense University, i + 12, CNIO, CIBERONC, CB16/12/00369 Madrid Spain., Oriol A; Institut Català d'Oncologia, Institut Josep Carreras, Hospital Germans Trias I Pujol Barcelona Spain., Blanchard MJ; Hematology Department Hospital Ramón y Cajal Madrid Spain., Ríos-Tamayo R; Hospital Universitario Virgen de las Nievels, Ibs Granada Spain., Sureda A; Institut Catalá d'Oncologia- l'Hospitalet, IDIBELL, Universitat de Barcelona Barcelona Spain., Lakhwani S; Hospital Universitario de Canarias Santa Cruz de Tenerife Spain., de la Rubia J; Hematology Department University Hospital La Fe and School of Medicine and Dentistry, Catholic University of Valencia, CIBERONC CD16/12/00284 Valencia Spain., Cabañas V; Hospital Universitario Virgen de la Arrixaca, IMIB Murcia Spain., de Arriba F; Hospital Morales Meseguer, IMIB-Pascual Parrilla, Universidad de Murcia Murcia Spain., Paricio M; Hospital Clínico Universitario Lozano Blesa, Instituto Investigacion Sanitaria Aragon Zaragoza Spain., Iñigo MB; Hospital Clínico San Carlos Madrid Spain., González-Calle V; Hematology Department IBSAL, Instituto de Biología Molecular y Celular del Cáncer-Consejo Superior de Investigaciones Científicas (IBMCC-CSIC), Centro de Investigación Biomédica en Red de Cáncer (CIBERONC) Salamanca Spain., Ocio EM; Hospital Universitario Marqués de Valdecilla (IDIVAL), Universidad de Cantabria Santander Spain., Castro S; Clinical Biochemistry Department Hospital Universitario de Salamanca Salamanca Spain., Bargay J; Hospital Universitario Son Llàtzer, IdIsBa Palma de Mallorca Spain., Bladé J; Hospital Clinic, Institut d'Investigacions Biomédiques August Pi I Sunyer (IDIBAPS) Barcelona Spain., San Miguel JF; Clínica Universidad de Navarra, CUN, CIMA, IDISNA, CIBERONC CB16/12/00369 Pamplona Spain., Lahuerta JJ; Hospital Universitario 12 de Octubre, Complutense University, i + 12, CNIO, CIBERONC, CB16/12/00369 Madrid Spain., Mateos MV; Hematology Department IBSAL, Instituto de Biología Molecular y Celular del Cáncer-Consejo Superior de Investigaciones Científicas (IBMCC-CSIC), Centro de Investigación Biomédica en Red de Cáncer (CIBERONC) Salamanca Spain.
Source: HemaSphere [Hemasphere] 2026 Feb 18; Vol. 10 (2), pp. e70301. Date of Electronic Publication: 2026 Feb 18 (Print Publication: 2026).
Publication Type: Letter
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101740619 Publication Model: eCollection Cited Medium: Internet ISSN: 2572-9241 (Electronic) Linking ISSN: 25729241 NLM ISO Abbreviation: Hemasphere Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Puig+N%22">Puig N</searchLink>; Hematology Department IBSAL, Instituto de Biología Molecular y Celular del Cáncer-Consejo Superior de Investigaciones Científicas (IBMCC-CSIC), Centro de Investigación Biomédica en Red de Cáncer (CIBERONC) Salamanca Spain.<br /><searchLink fieldCode="AU" term="%22Agulló+C%22">Agulló C</searchLink>; Clinical Biochemistry Department Hospital Universitario de Salamanca Salamanca Spain.<br /><searchLink fieldCode="AU" term="%22Paiva+B%22">Paiva B</searchLink>; Clínica Universidad de Navarra, CUN, CIMA, IDISNA, CIBERONC CB16/12/00369 Pamplona Spain.<br /><searchLink fieldCode="AU" term="%22Cedena+MT%22">Cedena MT</searchLink>; Hospital Universitario 12 de Octubre, Complutense University, i + 12, CNIO, CIBERONC, CB16/12/00369 Madrid Spain.<br /><searchLink fieldCode="AU" term="%22Rosiñol+L%22">Rosiñol L</searchLink>; Hospital Clinic, Institut d'Investigacions Biomédiques August Pi I Sunyer (IDIBAPS) Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Contreras+T%22">Contreras T</searchLink>; Clinical Biochemistry Department Hospital Universitario de Salamanca Salamanca Spain.<br /><searchLink fieldCode="AU" term="%22Martínez-López+J%22">Martínez-López J</searchLink>; Hospital Universitario 12 de Octubre, Complutense University, i + 12, CNIO, CIBERONC, CB16/12/00369 Madrid Spain.<br /><searchLink fieldCode="AU" term="%22Oriol+A%22">Oriol A</searchLink>; Institut Català d'Oncologia, Institut Josep Carreras, Hospital Germans Trias I Pujol Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Blanchard+MJ%22">Blanchard MJ</searchLink>; Hematology Department Hospital Ramón y Cajal Madrid Spain.<br /><searchLink fieldCode="AU" term="%22Ríos-Tamayo+R%22">Ríos-Tamayo R</searchLink>; Hospital Universitario Virgen de las Nievels, Ibs Granada Spain.<br /><searchLink fieldCode="AU" term="%22Sureda+A%22">Sureda A</searchLink>; Institut Catalá d'Oncologia- l'Hospitalet, IDIBELL, Universitat de Barcelona Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Lakhwani+S%22">Lakhwani S</searchLink>; Hospital Universitario de Canarias Santa Cruz de Tenerife Spain.<br /><searchLink fieldCode="AU" term="%22de+la+Rubia+J%22">de la Rubia J</searchLink>; Hematology Department University Hospital La Fe and School of Medicine and Dentistry, Catholic University of Valencia, CIBERONC CD16/12/00284 Valencia Spain.<br /><searchLink fieldCode="AU" term="%22Cabañas+V%22">Cabañas V</searchLink>; Hospital Universitario Virgen de la Arrixaca, IMIB Murcia Spain.<br /><searchLink fieldCode="AU" term="%22de+Arriba+F%22">de Arriba F</searchLink>; Hospital Morales Meseguer, IMIB-Pascual Parrilla, Universidad de Murcia Murcia Spain.<br /><searchLink fieldCode="AU" term="%22Paricio+M%22">Paricio M</searchLink>; Hospital Clínico Universitario Lozano Blesa, Instituto Investigacion Sanitaria Aragon Zaragoza Spain.<br /><searchLink fieldCode="AU" term="%22Iñigo+MB%22">Iñigo MB</searchLink>; Hospital Clínico San Carlos Madrid Spain.<br /><searchLink fieldCode="AU" term="%22González-Calle+V%22">González-Calle V</searchLink>; Hematology Department IBSAL, Instituto de Biología Molecular y Celular del Cáncer-Consejo Superior de Investigaciones Científicas (IBMCC-CSIC), Centro de Investigación Biomédica en Red de Cáncer (CIBERONC) Salamanca Spain.<br /><searchLink fieldCode="AU" term="%22Ocio+EM%22">Ocio EM</searchLink>; Hospital Universitario Marqués de Valdecilla (IDIVAL), Universidad de Cantabria Santander Spain.<br /><searchLink fieldCode="AU" term="%22Castro+S%22">Castro S</searchLink>; Clinical Biochemistry Department Hospital Universitario de Salamanca Salamanca Spain.<br /><searchLink fieldCode="AU" term="%22Bargay+J%22">Bargay J</searchLink>; Hospital Universitario Son Llàtzer, IdIsBa Palma de Mallorca Spain.<br /><searchLink fieldCode="AU" term="%22Bladé+J%22">Bladé J</searchLink>; Hospital Clinic, Institut d'Investigacions Biomédiques August Pi I Sunyer (IDIBAPS) Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22San+Miguel+JF%22">San Miguel JF</searchLink>; Clínica Universidad de Navarra, CUN, CIMA, IDISNA, CIBERONC CB16/12/00369 Pamplona Spain.<br /><searchLink fieldCode="AU" term="%22Lahuerta+JJ%22">Lahuerta JJ</searchLink>; Hospital Universitario 12 de Octubre, Complutense University, i + 12, CNIO, CIBERONC, CB16/12/00369 Madrid Spain.<br /><searchLink fieldCode="AU" term="%22Mateos+MV%22">Mateos MV</searchLink>; Hematology Department IBSAL, Instituto de Biología Molecular y Celular del Cáncer-Consejo Superior de Investigaciones Científicas (IBMCC-CSIC), Centro de Investigación Biomédica en Red de Cáncer (CIBERONC) Salamanca Spain.
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