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Crosstalk between EZH2 and DNA methylation mediates neuroendocrine prostate cancer lineage plasticity.

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Title: Crosstalk between EZH2 and DNA methylation mediates neuroendocrine prostate cancer lineage plasticity.
Authors: Singh R; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Venkadakrishnan VB; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Imada E; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Yamada Y; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Brady NJ; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Dunmore KE; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.; Biochemistry, Cellular, and Molecular Biology Graduate Program, Weill Cornell Medicine, New York, NY, USA., Garner R; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.; Biochemistry, Cellular, and Molecular Biology Graduate Program, Weill Cornell Medicine, New York, NY, USA., Booker MA; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA, USA., Hanratty B; Division of Human Biology, Fred Hutchinson Cancer Center, Seattle, WA, USA., Haffner MC; Division of Human Biology, Fred Hutchinson Cancer Center, Seattle, WA, USA.; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA., Tolstorukov MY; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA, USA., Marchionni L; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Robinson BD; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Rickman DS; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA. dsr2005@med.cornell.edu.; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA. dsr2005@med.cornell.edu., Beltran H; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. himisha_beltran@dfci.harvard.edu.; Harvard Medical School, Boston, MA, USA. himisha_beltran@dfci.harvard.edu.; The Broad Institute of MIT and Harvard, Cambridge, MA, USA. himisha_beltran@dfci.harvard.edu.
Source: Nature communications [Nat Commun] 2026 Feb 21; Vol. 17 (1). Date of Electronic Publication: 2026 Feb 21.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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