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In Vivo Clearance of Immune Complexes: Insights Into Human Drug/Anti-Drug Antibody Complex Clearance Dynamics.

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Title: In Vivo Clearance of Immune Complexes: Insights Into Human Drug/Anti-Drug Antibody Complex Clearance Dynamics.
Authors: Opolka-Hoffmann E; Pharmaceutical Sciences, Roche Pharma Research and Early Development, Roche Innovation Center Munich, Roche Diagnostics GmbH, Nonnenwald 2, DE-82377, Penzberg, Germany. Eugenia.opolka-hoffmann@roche.com., Fowler S; Pharmaceutical Sciences, Roche Pharma Research and Early Development, Roche Innovation Center Basel, F.Hoffmann-La Roche Ltd, CH-4070, Basel, Switzerland., Bach T; Pharmaceutical Sciences, Roche Pharma Research and Early Development, Roche Innovation Center Munich, Roche Diagnostics GmbH, Nonnenwald 2, DE-82377, Penzberg, Germany., Jordan G; Pharmaceutical Sciences, Roche Pharma Research and Early Development, Roche Innovation Center Munich, Roche Diagnostics GmbH, Nonnenwald 2, DE-82377, Penzberg, Germany., Staack RF; Pharmaceutical Sciences, Roche Pharma Research and Early Development, Roche Innovation Center Munich, Roche Diagnostics GmbH, Nonnenwald 2, DE-82377, Penzberg, Germany.
Source: The AAPS journal [AAPS J] 2026 Feb 20; Vol. 28 (2). Date of Electronic Publication: 2026 Feb 20.
Publication Type: Journal Article; Clinical Trial, Phase I
Journal Info: Publisher: American Association of Pharmaceutical Scientists Country of Publication: United States NLM ID: 101223209 Publication Model: Electronic Cited Medium: Internet ISSN: 1550-7416 (Electronic) Linking ISSN: 15507416 NLM ISO Abbreviation: AAPS J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Opolka-Hoffmann+E%22">Opolka-Hoffmann E</searchLink>; Pharmaceutical Sciences, Roche Pharma Research and Early Development, Roche Innovation Center Munich, Roche Diagnostics GmbH, Nonnenwald 2, DE-82377, Penzberg, Germany. Eugenia.opolka-hoffmann@roche.com.<br /><searchLink fieldCode="AU" term="%22Fowler+S%22">Fowler S</searchLink>; Pharmaceutical Sciences, Roche Pharma Research and Early Development, Roche Innovation Center Basel, F.Hoffmann-La Roche Ltd, CH-4070, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bach+T%22">Bach T</searchLink>; Pharmaceutical Sciences, Roche Pharma Research and Early Development, Roche Innovation Center Munich, Roche Diagnostics GmbH, Nonnenwald 2, DE-82377, Penzberg, Germany.<br /><searchLink fieldCode="AU" term="%22Jordan+G%22">Jordan G</searchLink>; Pharmaceutical Sciences, Roche Pharma Research and Early Development, Roche Innovation Center Munich, Roche Diagnostics GmbH, Nonnenwald 2, DE-82377, Penzberg, Germany.<br /><searchLink fieldCode="AU" term="%22Staack+RF%22">Staack RF</searchLink>; Pharmaceutical Sciences, Roche Pharma Research and Early Development, Roche Innovation Center Munich, Roche Diagnostics GmbH, Nonnenwald 2, DE-82377, Penzberg, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101223209%22">The AAPS journal</searchLink> [AAPS J] 2026 Feb 20; Vol. 28 (2). <i>Date of Electronic Publication: </i>2026 Feb 20.
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