Gut microbiota and metabolite disruption during breast cancer chemotherapy is associated with peripheral neuropathy sensory symptoms and pain.

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Title: Gut microbiota and metabolite disruption during breast cancer chemotherapy is associated with peripheral neuropathy sensory symptoms and pain.
Authors: Beales JT; Institute of Brain, Behavior and Immunology, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA; Neuroscience Graduate Program, The Ohio State University, Columbus, OH, USA; Medical Scientist Training Program, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA., Mohanty V; Department of Chemistry, University of Illinois Chicago, Chicago, IL, USA., Seng MM; Institute of Brain, Behavior and Immunology, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA., Tapp ZM; Institute of Brain, Behavior and Immunology, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA., Sardesai SD; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA., Williams NO; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA., Gatti-Mays ME; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA., Stover DG; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA., Sudheendra PK; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA., Wesolowski R; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA., Bailey MT; Institute of Brain, Behavior and Immunology, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA; Center for Microbial Pathogenesis, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA; Department of Pediatrics, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA., Ni A; Division of Biostatistics, College of Public Health, The Ohio State University, Columbus, OH, USA., Cologna SM; Department of Chemistry, University of Illinois Chicago, Chicago, IL, USA., Pyter LM; Institute of Brain, Behavior and Immunology, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA; Department of Psychiatry and Behavioral Health, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA. Electronic address: leah.pyter@osumc.edu.
Source: Brain, behavior, and immunity [Brain Behav Immun] 2026 Jul; Vol. 135, pp. 106489. Date of Electronic Publication: 2026 Feb 19.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8800478 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2139 (Electronic) Linking ISSN: 08891591 NLM ISO Abbreviation: Brain Behav Immun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1090-2139
DOI:10.1016/j.bbi.2026.106489