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BAP1 Loss Induces Senescence and Enhances the Response to Radiation Therapy and Senolytics.

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Title: BAP1 Loss Induces Senescence and Enhances the Response to Radiation Therapy and Senolytics.
Authors: Elsayed AM; Havener Eye Institute, Department of Ophthalmology and Visual Science, The Ohio State University Wexner Medical Center, Columbus, OH, 43210, USA.; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Nasr City, Cairo, 11651, Egypt., Mosbeh A; Havener Eye Institute, Department of Ophthalmology and Visual Science, The Ohio State University Wexner Medical Center, Columbus, OH, 43210, USA.; Pathology Department, National Liver Institute, Menoufia University, Shibin Al Kawm, Egypt., Eltasawi EG; Bioinformatics Group, Center for Informatics Sciences (CIS), School of Information Technology and Computer Science (ITCS), Nile University, Giza, Egypt., Hanpude P; Havener Eye Institute, Department of Ophthalmology and Visual Science, The Ohio State University Wexner Medical Center, Columbus, OH, 43210, USA.; Department of Biochemistry and Molecular Biology, Robert Wood Johnson Medical school, Rutgers University, Piscataway, NJ 088540, USA., Uddin MN; Havener Eye Institute, Department of Ophthalmology and Visual Science, The Ohio State University Wexner Medical Center, Columbus, OH, 43210, USA., Cebulla CM; Havener Eye Institute, Department of Ophthalmology and Visual Science, The Ohio State University Wexner Medical Center, Columbus, OH, 43210, USA., Abdel-Rahman MH; Havener Eye Institute, Department of Ophthalmology and Visual Science, The Ohio State University Wexner Medical Center, Columbus, OH, 43210, USA.; Division of Human Genetics, Department of Internal Medicine, The Ohio State University Columbus, OH, 43210, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Feb 09. Date of Electronic Publication: 2026 Feb 09.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Elsayed+AM%22">Elsayed AM</searchLink>; Havener Eye Institute, Department of Ophthalmology and Visual Science, The Ohio State University Wexner Medical Center, Columbus, OH, 43210, USA.; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Nasr City, Cairo, 11651, Egypt.<br /><searchLink fieldCode="AU" term="%22Mosbeh+A%22">Mosbeh A</searchLink>; Havener Eye Institute, Department of Ophthalmology and Visual Science, The Ohio State University Wexner Medical Center, Columbus, OH, 43210, USA.; Pathology Department, National Liver Institute, Menoufia University, Shibin Al Kawm, Egypt.<br /><searchLink fieldCode="AU" term="%22Eltasawi+EG%22">Eltasawi EG</searchLink>; Bioinformatics Group, Center for Informatics Sciences (CIS), School of Information Technology and Computer Science (ITCS), Nile University, Giza, Egypt.<br /><searchLink fieldCode="AU" term="%22Hanpude+P%22">Hanpude P</searchLink>; Havener Eye Institute, Department of Ophthalmology and Visual Science, The Ohio State University Wexner Medical Center, Columbus, OH, 43210, USA.; Department of Biochemistry and Molecular Biology, Robert Wood Johnson Medical school, Rutgers University, Piscataway, NJ 088540, USA.<br /><searchLink fieldCode="AU" term="%22Uddin+MN%22">Uddin MN</searchLink>; Havener Eye Institute, Department of Ophthalmology and Visual Science, The Ohio State University Wexner Medical Center, Columbus, OH, 43210, USA.<br /><searchLink fieldCode="AU" term="%22Cebulla+CM%22">Cebulla CM</searchLink>; Havener Eye Institute, Department of Ophthalmology and Visual Science, The Ohio State University Wexner Medical Center, Columbus, OH, 43210, USA.<br /><searchLink fieldCode="AU" term="%22Abdel-Rahman+MH%22">Abdel-Rahman MH</searchLink>; Havener Eye Institute, Department of Ophthalmology and Visual Science, The Ohio State University Wexner Medical Center, Columbus, OH, 43210, USA.; Division of Human Genetics, Department of Internal Medicine, The Ohio State University Columbus, OH, 43210, USA.
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        Value: 10.64898/2026.02.05.704104
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              Text: 2026 Feb 09
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