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Blinatumomab-driven T-cell activation in αβ and γδ T-cell subsets: insights from in vitro assays.

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Title: Blinatumomab-driven T-cell activation in αβ and γδ T-cell subsets: insights from in vitro assays.
Authors: Kelm M; Medical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany., Nasr N; Institute of Immunology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany., Bendig S; Medical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.; Clinical Research Unit Towards a Cure for Adults and Children with Acute Lymphoblastic Leukemia (CATCH ALL) (KFO 5010), Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), Kiel, Germany.; University Cancer Center Schleswig-Holstein (UCCSH), University Hospital Schleswig-Holstein, Kiel, Germany., Kabelitz D; Institute of Immunology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany., Lustig M; Clinical Research Unit Towards a Cure for Adults and Children with Acute Lymphoblastic Leukemia (CATCH ALL) (KFO 5010), Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), Kiel, Germany.; University Cancer Center Schleswig-Holstein (UCCSH), University Hospital Schleswig-Holstein, Kiel, Germany.; Medical Department II, Division of Stem Cell Transplantation and Cellular Immunotherapies, University Hospital Schleswig-Holstein and Christian-Albrechts-University of Kiel, Kiel, Germany., Trautmann H; Medical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany., Laqua A; Medical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany., Peters C; Institute of Immunology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany., Wesch D; Institute of Immunology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany., Oberg HH; Institute of Immunology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany., Janssen O; Institute of Immunology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany., Valerius T; Clinical Research Unit Towards a Cure for Adults and Children with Acute Lymphoblastic Leukemia (CATCH ALL) (KFO 5010), Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), Kiel, Germany.; University Cancer Center Schleswig-Holstein (UCCSH), University Hospital Schleswig-Holstein, Kiel, Germany.; Medical Department II, Division of Stem Cell Transplantation and Cellular Immunotherapies, University Hospital Schleswig-Holstein and Christian-Albrechts-University of Kiel, Kiel, Germany., Baldus CD; Medical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.; Clinical Research Unit Towards a Cure for Adults and Children with Acute Lymphoblastic Leukemia (CATCH ALL) (KFO 5010), Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), Kiel, Germany.; University Cancer Center Schleswig-Holstein (UCCSH), University Hospital Schleswig-Holstein, Kiel, Germany., Scheffold A; Institute of Immunology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.; Clinical Research Unit Towards a Cure for Adults and Children with Acute Lymphoblastic Leukemia (CATCH ALL) (KFO 5010), Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), Kiel, Germany.; Technische Universität Berlin, Institute for Biotechnology, Berlin, Germany., Brüggemann M; Medical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.; Clinical Research Unit Towards a Cure for Adults and Children with Acute Lymphoblastic Leukemia (CATCH ALL) (KFO 5010), Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), Kiel, Germany.; University Cancer Center Schleswig-Holstein (UCCSH), University Hospital Schleswig-Holstein, Kiel, Germany., Chitadze G; Medical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.; Clinical Research Unit Towards a Cure for Adults and Children with Acute Lymphoblastic Leukemia (CATCH ALL) (KFO 5010), Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), Kiel, Germany.; University Cancer Center Schleswig-Holstein (UCCSH), University Hospital Schleswig-Holstein, Kiel, Germany.
Source: Frontiers in immunology [Front Immunol] 2026 Feb 06; Vol. 17, pp. 1739493. Date of Electronic Publication: 2026 Feb 06 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Blinatumomab-driven T-cell activation in αβ and γδ T-cell subsets: insights from in vitro assays.
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  Data: <searchLink fieldCode="AU" term="%22Kelm+M%22">Kelm M</searchLink>; Medical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Nasr+N%22">Nasr N</searchLink>; Institute of Immunology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Bendig+S%22">Bendig S</searchLink>; Medical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.; Clinical Research Unit Towards a Cure for Adults and Children with Acute Lymphoblastic Leukemia (CATCH ALL) (KFO 5010), Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), Kiel, Germany.; University Cancer Center Schleswig-Holstein (UCCSH), University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Kabelitz+D%22">Kabelitz D</searchLink>; Institute of Immunology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Lustig+M%22">Lustig M</searchLink>; Clinical Research Unit Towards a Cure for Adults and Children with Acute Lymphoblastic Leukemia (CATCH ALL) (KFO 5010), Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), Kiel, Germany.; University Cancer Center Schleswig-Holstein (UCCSH), University Hospital Schleswig-Holstein, Kiel, Germany.; Medical Department II, Division of Stem Cell Transplantation and Cellular Immunotherapies, University Hospital Schleswig-Holstein and Christian-Albrechts-University of Kiel, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Trautmann+H%22">Trautmann H</searchLink>; Medical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Laqua+A%22">Laqua A</searchLink>; Medical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Peters+C%22">Peters C</searchLink>; Institute of Immunology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Wesch+D%22">Wesch D</searchLink>; Institute of Immunology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Oberg+HH%22">Oberg HH</searchLink>; Institute of Immunology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Janssen+O%22">Janssen O</searchLink>; Institute of Immunology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Valerius+T%22">Valerius T</searchLink>; Clinical Research Unit Towards a Cure for Adults and Children with Acute Lymphoblastic Leukemia (CATCH ALL) (KFO 5010), Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), Kiel, Germany.; University Cancer Center Schleswig-Holstein (UCCSH), University Hospital Schleswig-Holstein, Kiel, Germany.; Medical Department II, Division of Stem Cell Transplantation and Cellular Immunotherapies, University Hospital Schleswig-Holstein and Christian-Albrechts-University of Kiel, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Baldus+CD%22">Baldus CD</searchLink>; Medical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.; Clinical Research Unit Towards a Cure for Adults and Children with Acute Lymphoblastic Leukemia (CATCH ALL) (KFO 5010), Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), Kiel, Germany.; University Cancer Center Schleswig-Holstein (UCCSH), University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Scheffold+A%22">Scheffold A</searchLink>; Institute of Immunology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.; Clinical Research Unit Towards a Cure for Adults and Children with Acute Lymphoblastic Leukemia (CATCH ALL) (KFO 5010), Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), Kiel, Germany.; Technische Universität Berlin, Institute for Biotechnology, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Brüggemann+M%22">Brüggemann M</searchLink>; Medical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.; Clinical Research Unit Towards a Cure for Adults and Children with Acute Lymphoblastic Leukemia (CATCH ALL) (KFO 5010), Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), Kiel, Germany.; University Cancer Center Schleswig-Holstein (UCCSH), University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Chitadze+G%22">Chitadze G</searchLink>; Medical Department II, Hematology and Oncology, Christian-Albrechts University of Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.; Clinical Research Unit Towards a Cure for Adults and Children with Acute Lymphoblastic Leukemia (CATCH ALL) (KFO 5010), Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), Kiel, Germany.; University Cancer Center Schleswig-Holstein (UCCSH), University Hospital Schleswig-Holstein, Kiel, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Feb 06; Vol. 17, pp. 1739493. <i>Date of Electronic Publication: </i>2026 Feb 06 (<i>Print Publication: </i>2026).
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