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Association between shoulder joint radiation dose and arm morbidity in the randomized breast cancer trial SENOMAC.

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Title: Association between shoulder joint radiation dose and arm morbidity in the randomized breast cancer trial SENOMAC.
Authors: Alkner S; Department of Oncology, Faculty of Medicine, Institute of Clinical Sciences Lund, Lund University, Lund, Sweden; Skåne University Hospital Lund, Department of Hematology, Oncology and Radiation Physics, Lund, Sweden. Electronic address: sara.alkner@med.lu.se., Appelgren M; Department of Medical Epidemiology and Biostatistics. Karolinska Institutet, Stockholm, Sweden., Szulkin R; Department of Medical Epidemiology and Biostatistics. Karolinska Institutet, Stockholm, Sweden., Wieslander E; Radiation Physics, Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Sweden., Rogowski V; Radiation Physics, Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Sweden; Medical Radiation Physics, Department of Clinical Sciences Lund, Lund University, Lund, Sweden., Gustafsson CJ; Radiation Physics, Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Sweden; Department of Translational Medicine, Medical Radiation Physics, Lund University, Malmö, Sweden., Nissen HD; Department of Oncology, Vejle Hospital, University Hospital of Southern Denmark, Vejle, Denmark., Sackey H; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden; Department of Breast, Endocrine Tumors and Sarcoma, Karolinska Comprehensive Cancer Center, Karolinska University Hospital, Stockholm, Sweden., Lundstedt D; Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Department of Oncology at Sahlgrenska University Hospital, Gothenburg, Sweden., Andersson Y; Department of Surgery, Vastmanland Hospital Vasteras, Vasteras, Sweden; Centre for Clinical Research, Uppsala University and Region Vastmanland, Vastmanland Hospital Vasteras, Sweden., Bergkvist L; Centre for Clinical Research, Uppsala University and Region Vastmanland, Vastmanland Hospital Vasteras, Sweden., Frisell J; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden; Department of Breast, Endocrine Tumors and Sarcoma, Karolinska Comprehensive Cancer Center, Karolinska University Hospital, Stockholm, Sweden., Olofsson Bagge R; Sahlgrenska Center for Cancer Research, Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden., Sund M; Department of Surgery, University of Helsinki and Helsinki University Hospital, Finland; Department of Diagnostics and Intervention/ Surgery, Umeå University, Sweden., Rydén L; Department of Oncology, Faculty of Medicine, Institute of Clinical Sciences Lund, Lund University, Lund, Sweden; Skåne University Hospital, Department of Gastroenterology and Surgery, Malmö, Sweden., Offersen BV; Department of Oncology, Aarhus University Hospital, Aarhus University, Aarhus, Denmark; Department of Experimental Clinical Oncology, Danish Center for Particle Therapy, Aarhus, Denmark., de Boniface J; Department of Medical Epidemiology and Biostatistics. Karolinska Institutet, Stockholm, Sweden; Department of Surgery, Capio St. Goran's Hospital, Stockholm, Sweden.
Source: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology [Radiother Oncol] 2026 May; Vol. 218, pp. 111454. Date of Electronic Publication: 2026 Feb 21.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8407192 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0887 (Electronic) Linking ISSN: 01678140 NLM ISO Abbreviation: Radiother Oncol Subsets: MEDLINE
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  Data: Association between shoulder joint radiation dose and arm morbidity in the randomized breast cancer trial SENOMAC.
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  Data: <searchLink fieldCode="AU" term="%22Alkner+S%22">Alkner S</searchLink>; Department of Oncology, Faculty of Medicine, Institute of Clinical Sciences Lund, Lund University, Lund, Sweden; Skåne University Hospital Lund, Department of Hematology, Oncology and Radiation Physics, Lund, Sweden. Electronic address: sara.alkner@med.lu.se.<br /><searchLink fieldCode="AU" term="%22Appelgren+M%22">Appelgren M</searchLink>; Department of Medical Epidemiology and Biostatistics. Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Szulkin+R%22">Szulkin R</searchLink>; Department of Medical Epidemiology and Biostatistics. Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Wieslander+E%22">Wieslander E</searchLink>; Radiation Physics, Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Sweden.<br /><searchLink fieldCode="AU" term="%22Rogowski+V%22">Rogowski V</searchLink>; Radiation Physics, Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Sweden; Medical Radiation Physics, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Gustafsson+CJ%22">Gustafsson CJ</searchLink>; Radiation Physics, Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Sweden; Department of Translational Medicine, Medical Radiation Physics, Lund University, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Nissen+HD%22">Nissen HD</searchLink>; Department of Oncology, Vejle Hospital, University Hospital of Southern Denmark, Vejle, Denmark.<br /><searchLink fieldCode="AU" term="%22Sackey+H%22">Sackey H</searchLink>; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden; Department of Breast, Endocrine Tumors and Sarcoma, Karolinska Comprehensive Cancer Center, Karolinska University Hospital, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Lundstedt+D%22">Lundstedt D</searchLink>; Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Department of Oncology at Sahlgrenska University Hospital, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Andersson+Y%22">Andersson Y</searchLink>; Department of Surgery, Vastmanland Hospital Vasteras, Vasteras, Sweden; Centre for Clinical Research, Uppsala University and Region Vastmanland, Vastmanland Hospital Vasteras, Sweden.<br /><searchLink fieldCode="AU" term="%22Bergkvist+L%22">Bergkvist L</searchLink>; Centre for Clinical Research, Uppsala University and Region Vastmanland, Vastmanland Hospital Vasteras, Sweden.<br /><searchLink fieldCode="AU" term="%22Frisell+J%22">Frisell J</searchLink>; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden; Department of Breast, Endocrine Tumors and Sarcoma, Karolinska Comprehensive Cancer Center, Karolinska University Hospital, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Olofsson+Bagge+R%22">Olofsson Bagge R</searchLink>; Sahlgrenska Center for Cancer Research, Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Sund+M%22">Sund M</searchLink>; Department of Surgery, University of Helsinki and Helsinki University Hospital, Finland; Department of Diagnostics and Intervention/ Surgery, Umeå University, Sweden.<br /><searchLink fieldCode="AU" term="%22Rydén+L%22">Rydén L</searchLink>; Department of Oncology, Faculty of Medicine, Institute of Clinical Sciences Lund, Lund University, Lund, Sweden; Skåne University Hospital, Department of Gastroenterology and Surgery, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Offersen+BV%22">Offersen BV</searchLink>; Department of Oncology, Aarhus University Hospital, Aarhus University, Aarhus, Denmark; Department of Experimental Clinical Oncology, Danish Center for Particle Therapy, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22de+Boniface+J%22">de Boniface J</searchLink>; Department of Medical Epidemiology and Biostatistics. Karolinska Institutet, Stockholm, Sweden; Department of Surgery, Capio St. Goran's Hospital, Stockholm, Sweden.
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