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Chronic complication risk and benefits of fenofibrate in type 2 diabetes by a PPARα polymorphism (rs6008845, C/T): a FIELD trial substudy.

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Title: Chronic complication risk and benefits of fenofibrate in type 2 diabetes by a PPARα polymorphism (rs6008845, C/T): a FIELD trial substudy.
Authors: Januszewski AS; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia; Sydney Pharmacy School, The University of Sydney, Camperdown, NSW, Australia., Huang MLH; Baker Heart and Diabetes Institute, Melbourne, VIC, Australia., Mangani AS; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia., Ong KL; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia., Dalton C; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia., O'Connell RL; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia., Li L; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia., Sullivan DR; Department of Chemical Pathology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia; Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia., Strbenac D; Sydney Precision Data Science Centre, Charles Perkins Centre, The University of Sydney, Camperdown, NSW, Australia., Donoghoe MW; Clinical Research Unit and Kirby Institute, University of New South Wales, Kensington, NSW, Australia., Brown C; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia., Carroll LM; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia., Gebski V; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia., Scott RS; Christchurch Hospital, Christchurch, New Zealand; NZ Clinical Research Ltd, Christchurch, New Zealand., John Simes R; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia., Jenkins AJ; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia; Baker Heart and Diabetes Institute, Melbourne, VIC, Australia., Keech AC; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia. Electronic address: anthony.keech@sydney.edu.au.
Corporate Authors: FIELD trial investigators
Source: Diabetes research and clinical practice [Diabetes Res Clin Pract] 2026 Apr; Vol. 234, pp. 113168. Date of Electronic Publication: 2026 Feb 21.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8508335 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8227 (Electronic) Linking ISSN: 01688227 NLM ISO Abbreviation: Diabetes Res Clin Pract Subsets: MEDLINE
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  Data: Chronic complication risk and benefits of fenofibrate in type 2 diabetes by a PPARα polymorphism (rs6008845, C/T): a FIELD trial substudy.
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  Data: <searchLink fieldCode="AU" term="%22Januszewski+AS%22">Januszewski AS</searchLink>; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia; Sydney Pharmacy School, The University of Sydney, Camperdown, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Huang+MLH%22">Huang MLH</searchLink>; Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Mangani+AS%22">Mangani AS</searchLink>; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Ong+KL%22">Ong KL</searchLink>; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Dalton+C%22">Dalton C</searchLink>; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22O'Connell+RL%22">O'Connell RL</searchLink>; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Sullivan+DR%22">Sullivan DR</searchLink>; Department of Chemical Pathology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia; Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Strbenac+D%22">Strbenac D</searchLink>; Sydney Precision Data Science Centre, Charles Perkins Centre, The University of Sydney, Camperdown, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Donoghoe+MW%22">Donoghoe MW</searchLink>; Clinical Research Unit and Kirby Institute, University of New South Wales, Kensington, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Brown+C%22">Brown C</searchLink>; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Carroll+LM%22">Carroll LM</searchLink>; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Gebski+V%22">Gebski V</searchLink>; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Scott+RS%22">Scott RS</searchLink>; Christchurch Hospital, Christchurch, New Zealand; NZ Clinical Research Ltd, Christchurch, New Zealand.<br /><searchLink fieldCode="AU" term="%22John+Simes+R%22">John Simes R</searchLink>; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Jenkins+AJ%22">Jenkins AJ</searchLink>; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia; Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Keech+AC%22">Keech AC</searchLink>; NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW, Australia. Electronic address: anthony.keech@sydney.edu.au.
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