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Marrow leptin-LEPR signaling rewires mitochondrial oxidative metabolism to confer chemoresistance in acute myeloid leukemia.

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Title: Marrow leptin-LEPR signaling rewires mitochondrial oxidative metabolism to confer chemoresistance in acute myeloid leukemia.
Authors: Liao X; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China., Dai W; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China., Xu X; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China., Cai D; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China., Tan M; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China., Wang Z; Department of Colorectal Surgery, the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, 350005, China., Huang Y; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China., Hou D; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China., Liu J; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China., Wang L; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China., Wang J; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China., Wang X; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China., Zhang S; Fujian Institute of Hematology, Fujian Provincial Key Laboratory on Hematology, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China., Lin X; Key Laboratory of Gastrointestinal Cancer (Fujian Medical University), Ministry of Education, Fuzhou, Fujian, 350122, China. xlin@fjmu.edu.cn., Huang H; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China. huanghuif@fjmu.edu.cn.
Source: Cell death & disease [Cell Death Dis] 2026 Feb 23; Vol. 17 (1). Date of Electronic Publication: 2026 Feb 23.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Marrow leptin-LEPR signaling rewires mitochondrial oxidative metabolism to confer chemoresistance in acute myeloid leukemia.
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  Data: <searchLink fieldCode="AU" term="%22Liao+X%22">Liao X</searchLink>; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China.<br /><searchLink fieldCode="AU" term="%22Dai+W%22">Dai W</searchLink>; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China.<br /><searchLink fieldCode="AU" term="%22Xu+X%22">Xu X</searchLink>; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China.<br /><searchLink fieldCode="AU" term="%22Cai+D%22">Cai D</searchLink>; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China.<br /><searchLink fieldCode="AU" term="%22Tan+M%22">Tan M</searchLink>; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Department of Colorectal Surgery, the First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, 350005, China.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China.<br /><searchLink fieldCode="AU" term="%22Hou+D%22">Hou D</searchLink>; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; Fujian Institute of Hematology, Fujian Provincial Key Laboratory on Hematology, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China.<br /><searchLink fieldCode="AU" term="%22Lin+X%22">Lin X</searchLink>; Key Laboratory of Gastrointestinal Cancer (Fujian Medical University), Ministry of Education, Fuzhou, Fujian, 350122, China. xlin@fjmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Huang+H%22">Huang H</searchLink>; Central Laboratory, Fujian Medical University Union Hospital, Fuzhou, Fujian, 350001, China. huanghuif@fjmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2026 Feb 23; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Feb 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101524092 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-4889 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Death Dis <i>Subsets: </i>MEDLINE
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