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Comparative analysis of deep mutational scanning datasets in enteroviruses A and B identifies functional divergence and therapeutic targets.

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Title: Comparative analysis of deep mutational scanning datasets in enteroviruses A and B identifies functional divergence and therapeutic targets.
Authors: Álvarez-Rodríguez B; Institute for Integrative Systems Biology (I2SysBio), Universitat de Valencia-CSIC, Valencia, Spain., Bakhache W; Quantitative Virology and Evolution Unit, Laboratory of Viral Diseases, NIH-NIAID Division of Intramural Research, Bethesda, MD, USA., McCormick L; Quantitative Virology and Evolution Unit, Laboratory of Viral Diseases, NIH-NIAID Division of Intramural Research, Bethesda, MD, USA.; Department of Biology, University of Oxford, Oxford, UK., Geller R; Institute for Integrative Systems Biology (I2SysBio), Universitat de Valencia-CSIC, Valencia, Spain. ron.geller@csic.es., Dolan PT; Quantitative Virology and Evolution Unit, Laboratory of Viral Diseases, NIH-NIAID Division of Intramural Research, Bethesda, MD, USA. Patrick.Dolan@nih.gov.
Source: Nature ecology & evolution [Nat Ecol Evol] 2026 Mar; Vol. 10 (3), pp. 467-480. Date of Electronic Publication: 2026 Feb 23.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 101698577 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2397-334X (Electronic) Linking ISSN: 2397334X NLM ISO Abbreviation: Nat Ecol Evol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Comparative analysis of deep mutational scanning datasets in enteroviruses A and B identifies functional divergence and therapeutic targets.
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  Data: <searchLink fieldCode="AU" term="%22Álvarez-Rodríguez+B%22">Álvarez-Rodríguez B</searchLink>; Institute for Integrative Systems Biology (I2SysBio), Universitat de Valencia-CSIC, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Bakhache+W%22">Bakhache W</searchLink>; Quantitative Virology and Evolution Unit, Laboratory of Viral Diseases, NIH-NIAID Division of Intramural Research, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22McCormick+L%22">McCormick L</searchLink>; Quantitative Virology and Evolution Unit, Laboratory of Viral Diseases, NIH-NIAID Division of Intramural Research, Bethesda, MD, USA.; Department of Biology, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Geller+R%22">Geller R</searchLink>; Institute for Integrative Systems Biology (I2SysBio), Universitat de Valencia-CSIC, Valencia, Spain. ron.geller@csic.es.<br /><searchLink fieldCode="AU" term="%22Dolan+PT%22">Dolan PT</searchLink>; Quantitative Virology and Evolution Unit, Laboratory of Viral Diseases, NIH-NIAID Division of Intramural Research, Bethesda, MD, USA. Patrick.Dolan@nih.gov.
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  Data: <searchLink fieldCode="JN" term="%22101698577%22">Nature ecology & evolution</searchLink> [Nat Ecol Evol] 2026 Mar; Vol. 10 (3), pp. 467-480. <i>Date of Electronic Publication: </i>2026 Feb 23.
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        Value: 10.1038/s41559-026-02993-8
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              Text: 2026 Mar
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