Exploring neural correlates of automated speech-based cognitive markers through resting-state functional connectivity in aging and at-risk Alzheimer's disease.

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Title: Exploring neural correlates of automated speech-based cognitive markers through resting-state functional connectivity in aging and at-risk Alzheimer's disease.
Authors: Li Q; Department of Psychosomatic Medicine, Rostock University Medical Center, Gehlsheimer Str. 20, Rostock, 18147, Germany. Qingyue.Li@med.uni-rostock.de., Alexopoulou ZS; Cognition-Behavior-Technology Lab (CoBtek), Université Côte d'Azur, Nice, France., Dyrba M; German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany., Mallick E; ki:Elements GmbH, Saarbrücken, Germany., Tröger J; ki:Elements GmbH, Saarbrücken, Germany., Spruth E; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Berlin, Germany., Altenstein S; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Berlin, Germany., Bartels C; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, University of Göttingen, Göttingen, Germany., Glanz W; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-Von-Guericke University, Magdeburg, Germany., Incesoy EI; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany., Butryn M; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-Von-Guericke University, Magdeburg, Germany., Kilimann I; German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany., Sodenkamp S; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany., Maier F; Department of Psychiatry, Medical Faculty, University of Cologne, Cologne, Germany., Rostamzadeh A; Department of Psychiatry, Medical Faculty, University of Cologne, Cologne, Germany., Osterrath A; German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany.; Department of Neurology, Carl Gustav Carus, Tec, University Hospital, hnische Universität Dresden, Dresden, Germany., Priller J; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Berlin, Germany.; University of Edinburgh and UK DRI, Edinburgh, UK.; Department of Psychiatry and Psychotherapy, School of Medicine and Health, Technical University of Munich, and German Center for Mental Health (DZPG), Munich, Germany., Schneider A; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Clinic of Old Age Psychiatry and Cognitive Disorders, University Hospital Bonn and University of Bonn, Bonn, Germany., Wiltfang J; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, University of Göttingen, Göttingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Göttingen, Germany.; Department of Medical Sciences, Neurosciences and Signaling Group, Institute of Biomedicine (iBiMED), University of Aveiro, Aveiro, Portugal., Laske C; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany., Falkenburger B; German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany.; Department of Neurology, Carl Gustav Carus, Tec, University Hospital, hnische Universität Dresden, Dresden, Germany., Wagner M; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Clinic of Old Age Psychiatry and Cognitive Disorders, University Hospital Bonn and University of Bonn, Bonn, Germany., Duezel E; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-Von-Guericke University, Magdeburg, Germany., Spottke A; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Clinic for Parkinson's, Sleep and Movement Disorders, Centre for Neurology, University Hospital Bonn, Bonn, Germany., Petzold GC; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Vascular Neurology, University Hospital Bonn, Bonn, Germany., Jessen F; Department of Psychiatry, Medical Faculty, University of Cologne, Cologne, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Excellence Cluster On Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany., König A; Cognition-Behavior-Technology Lab (CoBtek), Université Côte d'Azur, Nice, France.; ki:Elements GmbH, Saarbrücken, Germany.; Centre Hospitalier Et Universitaire, Clinique Gériatrique du Cerveau Et du Mouvement, Centre Mémoire de Ressources Et de Recherche, Université Côte d'Azur, Nice, France., Köhler S; German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany., Teipel S; Department of Psychosomatic Medicine, Rostock University Medical Center, Gehlsheimer Str. 20, Rostock, 18147, Germany.; German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.
Corporate Authors: DELCODE, DESCRIBE study groups
Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2026 Feb 24; Vol. 18 (1). Date of Electronic Publication: 2026 Feb 24.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN: 1758-9193 (Electronic) NLM ISO Abbreviation: Alzheimers Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Exploring neural correlates of automated speech-based cognitive markers through resting-state functional connectivity in aging and at-risk Alzheimer's disease.
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  Data: <searchLink fieldCode="AU" term="%22Li+Q%22">Li Q</searchLink>; Department of Psychosomatic Medicine, Rostock University Medical Center, Gehlsheimer Str. 20, Rostock, 18147, Germany. Qingyue.Li@med.uni-rostock.de.<br /><searchLink fieldCode="AU" term="%22Alexopoulou+ZS%22">Alexopoulou ZS</searchLink>; Cognition-Behavior-Technology Lab (CoBtek), Université Côte d'Azur, Nice, France.<br /><searchLink fieldCode="AU" term="%22Dyrba+M%22">Dyrba M</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Mallick+E%22">Mallick E</searchLink>; ki:Elements GmbH, Saarbrücken, Germany.<br /><searchLink fieldCode="AU" term="%22Tröger+J%22">Tröger J</searchLink>; ki:Elements GmbH, Saarbrücken, Germany.<br /><searchLink fieldCode="AU" term="%22Spruth+E%22">Spruth E</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Altenstein+S%22">Altenstein S</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Bartels+C%22">Bartels C</searchLink>; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, University of Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Glanz+W%22">Glanz W</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-Von-Guericke University, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Incesoy+EI%22">Incesoy EI</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Butryn+M%22">Butryn M</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-Von-Guericke University, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Kilimann+I%22">Kilimann I</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Sodenkamp+S%22">Sodenkamp S</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Maier+F%22">Maier F</searchLink>; Department of Psychiatry, Medical Faculty, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Rostamzadeh+A%22">Rostamzadeh A</searchLink>; Department of Psychiatry, Medical Faculty, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Osterrath+A%22">Osterrath A</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany.; Department of Neurology, Carl Gustav Carus, Tec, University Hospital, hnische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Priller+J%22">Priller J</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Berlin, Germany.; University of Edinburgh and UK DRI, Edinburgh, UK.; Department of Psychiatry and Psychotherapy, School of Medicine and Health, Technical University of Munich, and German Center for Mental Health (DZPG), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Schneider+A%22">Schneider A</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Clinic of Old Age Psychiatry and Cognitive Disorders, University Hospital Bonn and University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Wiltfang+J%22">Wiltfang J</searchLink>; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, University of Göttingen, Göttingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Göttingen, Germany.; Department of Medical Sciences, Neurosciences and Signaling Group, Institute of Biomedicine (iBiMED), University of Aveiro, Aveiro, Portugal.<br /><searchLink fieldCode="AU" term="%22Laske+C%22">Laske C</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.; Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Falkenburger+B%22">Falkenburger B</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany.; Department of Neurology, Carl Gustav Carus, Tec, University Hospital, hnische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Wagner+M%22">Wagner M</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Clinic of Old Age Psychiatry and Cognitive Disorders, University Hospital Bonn and University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Duezel+E%22">Duezel E</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-Von-Guericke University, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Spottke+A%22">Spottke A</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Clinic for Parkinson's, Sleep and Movement Disorders, Centre for Neurology, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Petzold+GC%22">Petzold GC</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Vascular Neurology, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Jessen+F%22">Jessen F</searchLink>; Department of Psychiatry, Medical Faculty, University of Cologne, Cologne, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Excellence Cluster On Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22König+A%22">König A</searchLink>; Cognition-Behavior-Technology Lab (CoBtek), Université Côte d'Azur, Nice, France.; ki:Elements GmbH, Saarbrücken, Germany.; Centre Hospitalier Et Universitaire, Clinique Gériatrique du Cerveau Et du Mouvement, Centre Mémoire de Ressources Et de Recherche, Université Côte d'Azur, Nice, France.<br /><searchLink fieldCode="AU" term="%22Köhler+S%22">Köhler S</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Teipel+S%22">Teipel S</searchLink>; Department of Psychosomatic Medicine, Rostock University Medical Center, Gehlsheimer Str. 20, Rostock, 18147, Germany.; German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.
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