Transarterial Chemoembolization Combined With Camrelizumab and Rivoceranib for Unresectable Hepatocellular Carcinoma (CHANCE2005/CARES-005): A Randomized Phase II Trial.
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| Title: | Transarterial Chemoembolization Combined With Camrelizumab and Rivoceranib for Unresectable Hepatocellular Carcinoma (CHANCE2005/CARES-005): A Randomized Phase II Trial. |
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| Authors: | Zhu HD; Center of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China.; National Innovation Platform for Integration of Medical Engineering Education (NMEE) (Southeast University), Southeast University, Nanjing, China., Fan WJ; Department of Minimally Invasive Interventional Therapy, Liver Cancer Study and Service Group, Sun Yat-Sen University Cancer Center, Guangzhou, China., Zhao C; Department of Interventional Therapy, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, China., Wang S; Department of Interventional Radiology, Affiliated Hospital of Qingdao University, Qingdao, China., Li YL; Department of Intervention Medicine, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China., Jin ZC; Center of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China.; National Innovation Platform for Integration of Medical Engineering Education (NMEE) (Southeast University), Southeast University, Nanjing, China., Zhang ZW; Department of Interventional Radiology, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, China., Guo JH; Center of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China.; National Innovation Platform for Integration of Medical Engineering Education (NMEE) (Southeast University), Southeast University, Nanjing, China., Cheng HT; Department of Minimally Invasive Intervention, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China., Zhang Q; Center of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China.; National Innovation Platform for Integration of Medical Engineering Education (NMEE) (Southeast University), Southeast University, Nanjing, China., Lu J; Center of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China.; National Innovation Platform for Integration of Medical Engineering Education (NMEE) (Southeast University), Southeast University, Nanjing, China., Zeng YY; Department of Hepatobiliary Surgery, Mengchao Hepatobiliary Hospital, Fujian Medical University, Fuzhou, China., Lv WF; Department of Interventional Radiology, The First Affiliated Hospital, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China., Xu H; Department of Interventional Radiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China., Shao HB; Department of Radiology, The First Affiliated Hospital of China Medical University, Shenyang, China., Xu WG; Zhuhai Interventional Medical Center, Zhuhai Precision Medical Center, Zhuhai People's Hospital, Zhuhai Hospital Affiliated with Jinan University, Zhuhai, China., Zhao XY; Department of Interventional Radiology, Guizhou Cancer Hospital, Guiyang, China., Gu SZ; Department of Interventional Radiology, Hunan Cancer Hospital, Changsha, China., Lin HL; Department of Interventional Oncology, Fujian Medical University Cancer Hospital, Fujian Cancer Hospital, Fuzhou, China., Zheng WH; Department of Medical Imaging, Cancer Hospital of China Medical University, Liaoning Cancer Hospital and Institute, Shenyang, China., Piao LZ; Department of Oncology, The Affiliated Hospital of Yanbian University, Yanji, China., Song YS; Department of Interventional Radiology, Ganzhou People's Hospital, Ganzhou, China., Zhao JB; Interventional Department, Nanfang Hospital Affiliated to Southern Medical University, Guangzhou, China., Wang YC; National Innovation Platform for Integration of Medical Engineering Education (NMEE) (Southeast University), Southeast University, Nanjing, China.; Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China., Hou ZG; Department of Medical Affairs, Jiangsu Hengrui Pharmaceuticals Co., Ltd, Shanghai, China., Sun Y; Department of Medical Affairs, Jiangsu Hengrui Pharmaceuticals Co., Ltd, Shanghai, China., Guan N; Department of Medical Affairs, Jiangsu Hengrui Pharmaceuticals Co., Ltd, Shanghai, China., Huang M; Department of Minimally Invasive Interventional Therapy, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, China., Yang WZ; Department of Interventional Radiology, Union Hospital of Fujian Medical University, Fuzhou, China., Ji JS; Department of Radiology, Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, School of Medicine, Lishui Hospital of Zhejiang University, Lishui, China., Teng GJ; Center of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China.; National Innovation Platform for Integration of Medical Engineering Education (NMEE) (Southeast University), Southeast University, Nanjing, China.; Nurturing Center of Jiangsu Province for State Laboratory of AI Imaging & Interventional Radiology (Southeast University), Nanjing, China.; Basic Medicine Research and Innovation Center of Ministry of Education, Zhongda Hospital, Southeast University, Nanjing, China.; State Key Laboratory of Digital Medical Engineering, Southeast University, Nanjing, China. |
| Source: | Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2026 Apr 10; Vol. 44 (11), pp. 959-969. Date of Electronic Publication: 2026 Feb 24. |
| Publication Type: | Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial; Multicenter Study |
| Journal Info: | Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-7755 (Electronic) Linking ISSN: 0732183X NLM ISO Abbreviation: J Clin Oncol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41734362 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Transarterial Chemoembolization Combined With Camrelizumab and Rivoceranib for Unresectable Hepatocellular Carcinoma (CHANCE2005/CARES-005): A Randomized Phase II Trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Zhu+HD%22">Zhu HD</searchLink>; Center of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China.; National Innovation Platform for Integration of Medical Engineering Education (NMEE) (Southeast University), Southeast University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Fan+WJ%22">Fan WJ</searchLink>; Department of Minimally Invasive Interventional Therapy, Liver Cancer Study and Service Group, Sun Yat-Sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhao+C%22">Zhao C</searchLink>; Department of Interventional Therapy, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Wang+S%22">Wang S</searchLink>; Department of Interventional Radiology, Affiliated Hospital of Qingdao University, Qingdao, China.<br /><searchLink fieldCode="AU" term="%22Li+YL%22">Li YL</searchLink>; Department of Intervention Medicine, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.<br /><searchLink fieldCode="AU" term="%22Jin+ZC%22">Jin ZC</searchLink>; Center of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China.; National Innovation Platform for Integration of Medical Engineering Education (NMEE) (Southeast University), Southeast University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Zhang+ZW%22">Zhang ZW</searchLink>; Department of Interventional Radiology, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Guo+JH%22">Guo JH</searchLink>; Center of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China.; National Innovation Platform for Integration of Medical Engineering Education (NMEE) (Southeast University), Southeast University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Cheng+HT%22">Cheng HT</searchLink>; Department of Minimally Invasive Intervention, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Q%22">Zhang Q</searchLink>; Center of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China.; National Innovation Platform for Integration of Medical Engineering Education (NMEE) (Southeast University), Southeast University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Lu+J%22">Lu J</searchLink>; Center of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China.; National Innovation Platform for Integration of Medical Engineering Education (NMEE) (Southeast University), Southeast University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Zeng+YY%22">Zeng YY</searchLink>; Department of Hepatobiliary Surgery, Mengchao Hepatobiliary Hospital, Fujian Medical University, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Lv+WF%22">Lv WF</searchLink>; Department of Interventional Radiology, The First Affiliated Hospital, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.<br /><searchLink fieldCode="AU" term="%22Xu+H%22">Xu H</searchLink>; Department of Interventional Radiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.<br /><searchLink fieldCode="AU" term="%22Shao+HB%22">Shao HB</searchLink>; Department of Radiology, The First Affiliated Hospital of China Medical University, Shenyang, China.<br /><searchLink fieldCode="AU" term="%22Xu+WG%22">Xu WG</searchLink>; Zhuhai Interventional Medical Center, Zhuhai Precision Medical Center, Zhuhai People's Hospital, Zhuhai Hospital Affiliated with Jinan University, Zhuhai, China.<br /><searchLink fieldCode="AU" term="%22Zhao+XY%22">Zhao XY</searchLink>; Department of Interventional Radiology, Guizhou Cancer Hospital, Guiyang, China.<br /><searchLink fieldCode="AU" term="%22Gu+SZ%22">Gu SZ</searchLink>; Department of Interventional Radiology, Hunan Cancer Hospital, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Lin+HL%22">Lin HL</searchLink>; Department of Interventional Oncology, Fujian Medical University Cancer Hospital, Fujian Cancer Hospital, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Zheng+WH%22">Zheng WH</searchLink>; Department of Medical Imaging, Cancer Hospital of China Medical University, Liaoning Cancer Hospital and Institute, Shenyang, China.<br /><searchLink fieldCode="AU" term="%22Piao+LZ%22">Piao LZ</searchLink>; Department of Oncology, The Affiliated Hospital of Yanbian University, Yanji, China.<br /><searchLink fieldCode="AU" term="%22Song+YS%22">Song YS</searchLink>; Department of Interventional Radiology, Ganzhou People's Hospital, Ganzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhao+JB%22">Zhao JB</searchLink>; Interventional Department, Nanfang Hospital Affiliated to Southern Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+YC%22">Wang YC</searchLink>; National Innovation Platform for Integration of Medical Engineering Education (NMEE) (Southeast University), Southeast University, Nanjing, China.; Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Hou+ZG%22">Hou ZG</searchLink>; Department of Medical Affairs, Jiangsu Hengrui Pharmaceuticals Co., Ltd, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Sun+Y%22">Sun Y</searchLink>; Department of Medical Affairs, Jiangsu Hengrui Pharmaceuticals Co., Ltd, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Guan+N%22">Guan N</searchLink>; Department of Medical Affairs, Jiangsu Hengrui Pharmaceuticals Co., Ltd, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Huang+M%22">Huang M</searchLink>; Department of Minimally Invasive Interventional Therapy, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, China.<br /><searchLink fieldCode="AU" term="%22Yang+WZ%22">Yang WZ</searchLink>; Department of Interventional Radiology, Union Hospital of Fujian Medical University, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Ji+JS%22">Ji JS</searchLink>; Department of Radiology, Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, School of Medicine, Lishui Hospital of Zhejiang University, Lishui, China.<br /><searchLink fieldCode="AU" term="%22Teng+GJ%22">Teng GJ</searchLink>; Center of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China.; National Innovation Platform for Integration of Medical Engineering Education (NMEE) (Southeast University), Southeast University, Nanjing, China.; Nurturing Center of Jiangsu Province for State Laboratory of AI Imaging & Interventional Radiology (Southeast University), Nanjing, China.; Basic Medicine Research and Innovation Center of Ministry of Education, Zhongda Hospital, Southeast University, Nanjing, China.; State Key Laboratory of Digital Medical Engineering, Southeast University, Nanjing, China. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228309333%22">Journal of clinical oncology : official journal of the American Society of Clinical Oncology</searchLink> [J Clin Oncol] 2026 Apr 10; Vol. 44 (11), pp. 959-969. <i>Date of Electronic Publication: </i>2026 Feb 24. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial; Multicenter Study – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+of+Clinical+Oncology%22">American Society of Clinical Oncology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8309333 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1527-7755 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220732183X%22">0732183X </searchLink><i>NLM ISO Abbreviation: </i>J Clin Oncol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41734362 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1200/JCO-25-01796 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 959 Titles: – TitleFull: Transarterial Chemoembolization Combined With Camrelizumab and Rivoceranib for Unresectable Hepatocellular Carcinoma (CHANCE2005/CARES-005): A Randomized Phase II Trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Zhu HD – PersonEntity: Name: NameFull: Fan WJ – PersonEntity: Name: NameFull: Zhao C – PersonEntity: Name: NameFull: Wang S – PersonEntity: Name: NameFull: Li YL – PersonEntity: Name: NameFull: Jin ZC – PersonEntity: Name: NameFull: Zhang ZW – PersonEntity: Name: NameFull: Guo JH – PersonEntity: Name: NameFull: Cheng HT – PersonEntity: Name: NameFull: Zhang Q – PersonEntity: Name: NameFull: Lu J – PersonEntity: Name: NameFull: Zeng YY – PersonEntity: Name: NameFull: Lv WF – PersonEntity: Name: NameFull: Xu H – PersonEntity: Name: NameFull: Shao HB – PersonEntity: Name: NameFull: Xu WG – PersonEntity: Name: NameFull: Zhao XY – PersonEntity: Name: NameFull: Gu SZ – PersonEntity: Name: NameFull: Lin HL – PersonEntity: Name: NameFull: Zheng WH – PersonEntity: Name: NameFull: Piao LZ – PersonEntity: Name: NameFull: Song YS – PersonEntity: Name: NameFull: Zhao JB – PersonEntity: Name: NameFull: Wang YC – PersonEntity: Name: NameFull: Hou ZG – PersonEntity: Name: NameFull: Sun Y – PersonEntity: Name: NameFull: Guan N – PersonEntity: Name: NameFull: Huang M – PersonEntity: Name: NameFull: Yang WZ – PersonEntity: Name: NameFull: Ji JS – PersonEntity: Name: NameFull: Teng GJ IsPartOfRelationships: – BibEntity: Dates: – D: 10 M: 04 Text: 2026 Apr 10 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1527-7755 Numbering: – Type: volume Value: 44 – Type: issue Value: 11 Titles: – TitleFull: Journal of clinical oncology : official journal of the American Society of Clinical Oncology Type: main |
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