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Antiviral drug discovery and development: challenges and future directions.

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Title: Antiviral drug discovery and development: challenges and future directions.
Authors: Du S; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, P. R. China.; College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao, Shandong, P. R. China., Hu X; Institute of Frontier Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Qingdao, Shandong, P. R. China., Li P; Department of Medicinal Chemistry, School of Pharmacy, Qingdao University, Qingdao, China., Xu S; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, P. R. China., Kim M; Infectious Diseases Therapeutic Research Center, Korea Research Institute of Chemical Technology (KRICT), Daejeon, Republic of Korea. mkim@krict.re.kr., Liu X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, P. R. China. xinyongl@sdu.edu.cn., Zhan P; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, P. R. China. zhanpeng1982@sdu.edu.cn.
Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2026 Feb 25; Vol. 11 (1). Date of Electronic Publication: 2026 Feb 25.
Publication Type: Journal Article; Review
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Du+S%22">Du S</searchLink>; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, P. R. China.; College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao, Shandong, P. R. China.<br /><searchLink fieldCode="AU" term="%22Hu+X%22">Hu X</searchLink>; Institute of Frontier Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Qingdao, Shandong, P. R. China.<br /><searchLink fieldCode="AU" term="%22Li+P%22">Li P</searchLink>; Department of Medicinal Chemistry, School of Pharmacy, Qingdao University, Qingdao, China.<br /><searchLink fieldCode="AU" term="%22Xu+S%22">Xu S</searchLink>; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, P. R. China.<br /><searchLink fieldCode="AU" term="%22Kim+M%22">Kim M</searchLink>; Infectious Diseases Therapeutic Research Center, Korea Research Institute of Chemical Technology (KRICT), Daejeon, Republic of Korea. mkim@krict.re.kr.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, P. R. China. xinyongl@sdu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zhan+P%22">Zhan P</searchLink>; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, P. R. China. zhanpeng1982@sdu.edu.cn.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101676423 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2059-3635 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220593635%22">20593635 </searchLink><i>NLM ISO Abbreviation: </i>Signal Transduct Target Ther <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41392-025-02539-7
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              Text: 2026 Feb 25
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