An adenoviral-vectored vaccine protects mice against aerosol challenge with Yersinia pestis.

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Title: An adenoviral-vectored vaccine protects mice against aerosol challenge with Yersinia pestis.
Authors: Dold C; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, OX37LE Oxford, UK., Silva-Reyes L; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, OX37LE Oxford, UK., Kim YC; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, OX37LE Oxford, UK. Electronic address: young.kim@paediatrics.ox.ac.uk., Blackwell L; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, OX37LE Oxford, UK., Campos P; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, OX37LE Oxford, UK., Linder A; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, OX37LE Oxford, UK., Bridges-Webb A; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, OX37LE Oxford, UK., Kasanyinga M; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, OX37LE Oxford, UK., Lopez-Camacho C; Jenner Institute, University of Oxford, Old Road Campus Research Building, OX3 7DQ Oxford, UK., Challis A; United Kingdom Health Security Agency, Manor Farm Road, Porton Down, SP4 0JG Salisbury, UK., Hatch G; United Kingdom Health Security Agency, Manor Farm Road, Porton Down, SP4 0JG Salisbury, UK., Fotheringham S; United Kingdom Health Security Agency, Manor Farm Road, Porton Down, SP4 0JG Salisbury, UK., Beernink PT; Department of Pediatrics, University of California, San Francisco, Oakland, CA, USA., Hill AV; Jenner Institute, University of Oxford, Old Road Campus Research Building, OX3 7DQ Oxford, UK., Funnell SGP; United Kingdom Health Security Agency, Manor Farm Road, Porton Down, SP4 0JG Salisbury, UK; Quadram Institute Bioscience, Norwich Research Park, Norfolk, UK., Pollard AJ; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, OX37LE Oxford, UK., Rollier CS; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, OX37LE Oxford, UK; Faculty of Health and Medical Sciences, School of Biosciences, Department of Biochemistry and Physiology, University of Surrey, Guildford, UK.
Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2026 Jun 03; Vol. 34 (6), pp. 3518-3534. Date of Electronic Publication: 2026 Feb 24.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: An adenoviral-vectored vaccine protects mice against aerosol challenge with Yersinia pestis.
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  Data: <searchLink fieldCode="AU" term="%22Dold+C%22">Dold C</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, OX37LE Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Silva-Reyes+L%22">Silva-Reyes L</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, OX37LE Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Kim+YC%22">Kim YC</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, OX37LE Oxford, UK. Electronic address: young.kim@paediatrics.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Blackwell+L%22">Blackwell L</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, OX37LE Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Campos+P%22">Campos P</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, OX37LE Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Linder+A%22">Linder A</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, OX37LE Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Bridges-Webb+A%22">Bridges-Webb A</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, OX37LE Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Kasanyinga+M%22">Kasanyinga M</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, OX37LE Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Lopez-Camacho+C%22">Lopez-Camacho C</searchLink>; Jenner Institute, University of Oxford, Old Road Campus Research Building, OX3 7DQ Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Challis+A%22">Challis A</searchLink>; United Kingdom Health Security Agency, Manor Farm Road, Porton Down, SP4 0JG Salisbury, UK.<br /><searchLink fieldCode="AU" term="%22Hatch+G%22">Hatch G</searchLink>; United Kingdom Health Security Agency, Manor Farm Road, Porton Down, SP4 0JG Salisbury, UK.<br /><searchLink fieldCode="AU" term="%22Fotheringham+S%22">Fotheringham S</searchLink>; United Kingdom Health Security Agency, Manor Farm Road, Porton Down, SP4 0JG Salisbury, UK.<br /><searchLink fieldCode="AU" term="%22Beernink+PT%22">Beernink PT</searchLink>; Department of Pediatrics, University of California, San Francisco, Oakland, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hill+AV%22">Hill AV</searchLink>; Jenner Institute, University of Oxford, Old Road Campus Research Building, OX3 7DQ Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Funnell+SGP%22">Funnell SGP</searchLink>; United Kingdom Health Security Agency, Manor Farm Road, Porton Down, SP4 0JG Salisbury, UK; Quadram Institute Bioscience, Norwich Research Park, Norfolk, UK.<br /><searchLink fieldCode="AU" term="%22Pollard+AJ%22">Pollard AJ</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, OX37LE Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Rollier+CS%22">Rollier CS</searchLink>; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and the NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, OX37LE Oxford, UK; Faculty of Health and Medical Sciences, School of Biosciences, Department of Biochemistry and Physiology, University of Surrey, Guildford, UK.
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        Value: 10.1016/j.ymthe.2026.02.036
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        Text: English
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