Hypoxic development down-regulates endothelial Piezo1 via HIF1-α signaling and impairs Piezo1-mediated vasorelaxation.
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| Title: | Hypoxic development down-regulates endothelial Piezo1 via HIF1-α signaling and impairs Piezo1-mediated vasorelaxation. |
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| Authors: | Arenas GA; Facultad de Ciencias Biológ-icas, Pontificia Universidad Católica de Chile, Santiago, Chile., Cochrane ALK; Physiology, Development & Neuroscience, University of Cambridge, U.K., Cambridge., Peñaloza E; Instituto de Ciencias de la Salud, Universidad de O'Higgins, Rancagua, Chile., Paz AA; Instituto de Ciencias Biomédicas (ICBM), Facultad de Med-icina, Universidad de Chile, Santiago, Chile., Carrasco M; Instituto de Ciencias de la Salud, Universidad de O'Higgins, Rancagua, Chile., Iturriaga R; Instituto de Ciencias Biomédicas, Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Santiago, Chile., Giussani DA; Physiology, Development & Neuroscience, University of Cambridge, U.K., Cambridge.; Loke Centre for Trophoblast Research, University of Cambridge, U.K., Cambridge.; Cambridge Cardiovascular Strategic Research Initiative, University of Cambridge, U.K., Cambridge., Krause BJ; Instituto de Ciencias de la Salud, Universidad de O'Higgins, Rancagua, Chile. |
| Source: | Clinical science (London, England : 1979) [Clin Sci (Lond)] 2026 Apr 15; Vol. 140 (4), pp. 493-507. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Portland Press on behalf of the Medical Research Society and the Biochemical Society Country of Publication: England NLM ID: 7905731 Publication Model: Print Cited Medium: Internet ISSN: 1470-8736 (Electronic) Linking ISSN: 01435221 NLM ISO Abbreviation: Clin Sci (Lond) Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41736699 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Hypoxic development down-regulates endothelial Piezo1 via HIF1-α signaling and impairs Piezo1-mediated vasorelaxation. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Arenas+GA%22">Arenas GA</searchLink>; Facultad de Ciencias Biológ-icas, Pontificia Universidad Católica de Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Cochrane+ALK%22">Cochrane ALK</searchLink>; Physiology, Development & Neuroscience, University of Cambridge, U.K., Cambridge.<br /><searchLink fieldCode="AU" term="%22Peñaloza+E%22">Peñaloza E</searchLink>; Instituto de Ciencias de la Salud, Universidad de O'Higgins, Rancagua, Chile.<br /><searchLink fieldCode="AU" term="%22Paz+AA%22">Paz AA</searchLink>; Instituto de Ciencias Biomédicas (ICBM), Facultad de Med-icina, Universidad de Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Carrasco+M%22">Carrasco M</searchLink>; Instituto de Ciencias de la Salud, Universidad de O'Higgins, Rancagua, Chile.<br /><searchLink fieldCode="AU" term="%22Iturriaga+R%22">Iturriaga R</searchLink>; Instituto de Ciencias Biomédicas, Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Giussani+DA%22">Giussani DA</searchLink>; Physiology, Development & Neuroscience, University of Cambridge, U.K., Cambridge.; Loke Centre for Trophoblast Research, University of Cambridge, U.K., Cambridge.; Cambridge Cardiovascular Strategic Research Initiative, University of Cambridge, U.K., Cambridge.<br /><searchLink fieldCode="AU" term="%22Krause+BJ%22">Krause BJ</searchLink>; Instituto de Ciencias de la Salud, Universidad de O'Higgins, Rancagua, Chile. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227905731%22">Clinical science (London, England : 1979)</searchLink> [Clin Sci (Lond)] 2026 Apr 15; Vol. 140 (4), pp. 493-507. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Portland+Press+on+behalf+of+the+Medical+Research+Society+and+the+Biochemical+Society%22">Portland Press on behalf of the Medical Research Society and the Biochemical Society </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>7905731 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1470-8736 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201435221%22">01435221 </searchLink><i>NLM ISO Abbreviation: </i>Clin Sci (Lond) <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41736699 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1042/CS20258735 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 493 Titles: – TitleFull: Hypoxic development down-regulates endothelial Piezo1 via HIF1-α signaling and impairs Piezo1-mediated vasorelaxation. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Arenas GA – PersonEntity: Name: NameFull: Cochrane ALK – PersonEntity: Name: NameFull: Peñaloza E – PersonEntity: Name: NameFull: Paz AA – PersonEntity: Name: NameFull: Carrasco M – PersonEntity: Name: NameFull: Iturriaga R – PersonEntity: Name: NameFull: Giussani DA – PersonEntity: Name: NameFull: Krause BJ IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 04 Text: 2026 Apr 15 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1470-8736 Numbering: – Type: volume Value: 140 – Type: issue Value: 4 Titles: – TitleFull: Clinical science (London, England : 1979) Type: main |
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