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MCT4 mediates hypoxia-induced extracellular lactate release from IPF fibroblasts.

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Title: MCT4 mediates hypoxia-induced extracellular lactate release from IPF fibroblasts.
Authors: Nho RS; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States., Nielsen L; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States., Roberts J; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States., Diep S; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States., Taylor A; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States., Hager K; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States., Yengo R; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States., Rosas L; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States., Farkas L; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States., Prasad J; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States., Mebratu YA; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States., Rojas M; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States., Chan SY; Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States., Horowitz JC; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States.
Source: American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2026 Jul 01; Vol. 74 (7), pp. 924-935.
Publication Type: Journal Article
Journal Info: Publisher: American Thoracic Society Country of Publication: England NLM ID: 8917225 Publication Model: Print Cited Medium: Internet ISSN: 1535-4989 (Electronic) Linking ISSN: 10441549 NLM ISO Abbreviation: Am J Respir Cell Mol Biol Subsets: MEDLINE
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  Data: MCT4 mediates hypoxia-induced extracellular lactate release from IPF fibroblasts.
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  Data: <searchLink fieldCode="AU" term="%22Nho+RS%22">Nho RS</searchLink>; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States.<br /><searchLink fieldCode="AU" term="%22Nielsen+L%22">Nielsen L</searchLink>; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States.<br /><searchLink fieldCode="AU" term="%22Roberts+J%22">Roberts J</searchLink>; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States.<br /><searchLink fieldCode="AU" term="%22Diep+S%22">Diep S</searchLink>; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States.<br /><searchLink fieldCode="AU" term="%22Taylor+A%22">Taylor A</searchLink>; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States.<br /><searchLink fieldCode="AU" term="%22Hager+K%22">Hager K</searchLink>; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States.<br /><searchLink fieldCode="AU" term="%22Yengo+R%22">Yengo R</searchLink>; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States.<br /><searchLink fieldCode="AU" term="%22Rosas+L%22">Rosas L</searchLink>; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States.<br /><searchLink fieldCode="AU" term="%22Farkas+L%22">Farkas L</searchLink>; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States.<br /><searchLink fieldCode="AU" term="%22Prasad+J%22">Prasad J</searchLink>; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States.<br /><searchLink fieldCode="AU" term="%22Mebratu+YA%22">Mebratu YA</searchLink>; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States.<br /><searchLink fieldCode="AU" term="%22Rojas+M%22">Rojas M</searchLink>; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States.<br /><searchLink fieldCode="AU" term="%22Chan+SY%22">Chan SY</searchLink>; Department of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.<br /><searchLink fieldCode="AU" term="%22Horowitz+JC%22">Horowitz JC</searchLink>; Division of Pulmonary, Department of Internal Medicine and The Davis Heart and Lung Research Institute, Critical Care and Sleep Medicine, The Ohio State University, Columbus, OH, United States.
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              Text: 2026 Jul 01
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