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Heme limitation induces LHR2, an essential gene for Leishmania pathogenesis.

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Title: Heme limitation induces LHR2, an essential gene for Leishmania pathogenesis.
Authors: Juez-Castillo G; Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC, (IPBLN-CSIC), PTS Granada, Granada, Spain.; Universidad El Bosque, Faculty of Engineering, Osiris and Bioaxis Research Group, Bogotá D.C., Colombia., García-Hernández R; Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC, (IPBLN-CSIC), PTS Granada, Granada, Spain., Guerra-Arias D; Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC, (IPBLN-CSIC), PTS Granada, Granada, Spain.; Programa de Estudio y Control de Enfermedades Tropicales PECET, Faculty of Medicine, University of Antioquía, Medellín, Colombia., Vargas P; Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC, (IPBLN-CSIC), PTS Granada, Granada, Spain., Cabello-Donayre M; Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC, (IPBLN-CSIC), PTS Granada, Granada, Spain.; Universidad Internacional de La Rioja, Facultad de Ciencias de la Educación y Humanidades, Logroño, Spain., Monteiro JM; Centro de Investigaciones Biológicas Margarita Salas, CSIC, Madrid, Spain., Valencia-Vidal B; Universidad El Bosque, Faculty of Engineering, Osiris and Bioaxis Research Group, Bogotá D.C., Colombia., Rivas L; Centro de Investigaciones Biológicas Margarita Salas, CSIC, Madrid, Spain., Andrés-León E; Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC, (IPBLN-CSIC), PTS Granada, Granada, Spain., Castanys S; Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC, (IPBLN-CSIC), PTS Granada, Granada, Spain., Orrego LM; Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC, (IPBLN-CSIC), PTS Granada, Granada, Spain., Pérez-Victoria JM; Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC, (IPBLN-CSIC), PTS Granada, Granada, Spain.
Source: PLoS pathogens [PLoS Pathog] 2026 Feb 25; Vol. 22 (2), pp. e1013993. Date of Electronic Publication: 2026 Feb 25 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Heme limitation induces LHR2, an essential gene for Leishmania pathogenesis.
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  Data: <searchLink fieldCode="AU" term="%22Juez-Castillo+G%22">Juez-Castillo G</searchLink>; Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC, (IPBLN-CSIC), PTS Granada, Granada, Spain.; Universidad El Bosque, Faculty of Engineering, Osiris and Bioaxis Research Group, Bogotá D.C., Colombia.<br /><searchLink fieldCode="AU" term="%22García-Hernández+R%22">García-Hernández R</searchLink>; Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC, (IPBLN-CSIC), PTS Granada, Granada, Spain.<br /><searchLink fieldCode="AU" term="%22Guerra-Arias+D%22">Guerra-Arias D</searchLink>; Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC, (IPBLN-CSIC), PTS Granada, Granada, Spain.; Programa de Estudio y Control de Enfermedades Tropicales PECET, Faculty of Medicine, University of Antioquía, Medellín, Colombia.<br /><searchLink fieldCode="AU" term="%22Vargas+P%22">Vargas P</searchLink>; Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC, (IPBLN-CSIC), PTS Granada, Granada, Spain.<br /><searchLink fieldCode="AU" term="%22Cabello-Donayre+M%22">Cabello-Donayre M</searchLink>; Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC, (IPBLN-CSIC), PTS Granada, Granada, Spain.; Universidad Internacional de La Rioja, Facultad de Ciencias de la Educación y Humanidades, Logroño, Spain.<br /><searchLink fieldCode="AU" term="%22Monteiro+JM%22">Monteiro JM</searchLink>; Centro de Investigaciones Biológicas Margarita Salas, CSIC, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Valencia-Vidal+B%22">Valencia-Vidal B</searchLink>; Universidad El Bosque, Faculty of Engineering, Osiris and Bioaxis Research Group, Bogotá D.C., Colombia.<br /><searchLink fieldCode="AU" term="%22Rivas+L%22">Rivas L</searchLink>; Centro de Investigaciones Biológicas Margarita Salas, CSIC, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Andrés-León+E%22">Andrés-León E</searchLink>; Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC, (IPBLN-CSIC), PTS Granada, Granada, Spain.<br /><searchLink fieldCode="AU" term="%22Castanys+S%22">Castanys S</searchLink>; Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC, (IPBLN-CSIC), PTS Granada, Granada, Spain.<br /><searchLink fieldCode="AU" term="%22Orrego+LM%22">Orrego LM</searchLink>; Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC, (IPBLN-CSIC), PTS Granada, Granada, Spain.<br /><searchLink fieldCode="AU" term="%22Pérez-Victoria+JM%22">Pérez-Victoria JM</searchLink>; Instituto de Parasitología y Biomedicina 'López-Neyra', CSIC, (IPBLN-CSIC), PTS Granada, Granada, Spain.
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  Data: <searchLink fieldCode="JN" term="%22101238921%22">PLoS pathogens</searchLink> [PLoS Pathog] 2026 Feb 25; Vol. 22 (2), pp. e1013993. <i>Date of Electronic Publication: </i>2026 Feb 25 (<i>Print Publication: </i>2026).
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