View in EDS

Phase 1 Study of Rezatapopt, a p53 Reactivator, in TP53 Y220C-Mutated Tumors.

Saved in:
Bibliographic Details
Title: Phase 1 Study of Rezatapopt, a p53 Reactivator, in TP53 Y220C-Mutated Tumors.
Authors: Dumbrava EE; University of Texas M.D. Anderson Cancer Center, Houston., Shapiro GI; Dana-Farber Cancer Institute, Boston., Parikh AR; Massachusetts General Hospital, Boston., Johnson ML; Sarah Cannon Research Institute, Nashville., Tolcher AW; NEXT Oncology, Austin, Texas., Thompson JA; Fred Hutchinson Cancer Center, Seattle., El-Khoueiry AB; University of Southern California Norris Comprehensive Cancer Center, Los Angeles., Vandross AL; NEXT Oncology, Austin, Texas., Kummar S; Oregon Health and Science University Knight Cancer Institute, Portland., Shepard DR; Cleveland Clinic Foundation, Cleveland., LeDuke K; PMV Pharmaceuticals, Princeton, NJ., Sheehan L; PMV Pharmaceuticals, Princeton, NJ., Alland L; Leila Alland MD Consultancy, New York., Haque A; PMV Pharmaceuticals, Princeton, NJ., Jalota D; PMV Pharmaceuticals, Princeton, NJ., Fellous M; PMV Pharmaceuticals, Princeton, NJ., Schram AM; Memorial Sloan Kettering Cancer Center, New York.
Source: The New England journal of medicine [N Engl J Med] 2026 Feb 26; Vol. 394 (9), pp. 872-883.
Publication Type: Journal Article; Clinical Trial, Phase I; Multicenter Study
Journal Info: Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print Cited Medium: Internet ISSN: 1533-4406 (Electronic) Linking ISSN: 00284793 NLM ISO Abbreviation: N Engl J Med Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41740031
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Phase 1 Study of Rezatapopt, a p53 Reactivator, in TP53 Y220C-Mutated Tumors.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Dumbrava+EE%22">Dumbrava EE</searchLink>; University of Texas M.D. Anderson Cancer Center, Houston.<br /><searchLink fieldCode="AU" term="%22Shapiro+GI%22">Shapiro GI</searchLink>; Dana-Farber Cancer Institute, Boston.<br /><searchLink fieldCode="AU" term="%22Parikh+AR%22">Parikh AR</searchLink>; Massachusetts General Hospital, Boston.<br /><searchLink fieldCode="AU" term="%22Johnson+ML%22">Johnson ML</searchLink>; Sarah Cannon Research Institute, Nashville.<br /><searchLink fieldCode="AU" term="%22Tolcher+AW%22">Tolcher AW</searchLink>; NEXT Oncology, Austin, Texas.<br /><searchLink fieldCode="AU" term="%22Thompson+JA%22">Thompson JA</searchLink>; Fred Hutchinson Cancer Center, Seattle.<br /><searchLink fieldCode="AU" term="%22El-Khoueiry+AB%22">El-Khoueiry AB</searchLink>; University of Southern California Norris Comprehensive Cancer Center, Los Angeles.<br /><searchLink fieldCode="AU" term="%22Vandross+AL%22">Vandross AL</searchLink>; NEXT Oncology, Austin, Texas.<br /><searchLink fieldCode="AU" term="%22Kummar+S%22">Kummar S</searchLink>; Oregon Health and Science University Knight Cancer Institute, Portland.<br /><searchLink fieldCode="AU" term="%22Shepard+DR%22">Shepard DR</searchLink>; Cleveland Clinic Foundation, Cleveland.<br /><searchLink fieldCode="AU" term="%22LeDuke+K%22">LeDuke K</searchLink>; PMV Pharmaceuticals, Princeton, NJ.<br /><searchLink fieldCode="AU" term="%22Sheehan+L%22">Sheehan L</searchLink>; PMV Pharmaceuticals, Princeton, NJ.<br /><searchLink fieldCode="AU" term="%22Alland+L%22">Alland L</searchLink>; Leila Alland MD Consultancy, New York.<br /><searchLink fieldCode="AU" term="%22Haque+A%22">Haque A</searchLink>; PMV Pharmaceuticals, Princeton, NJ.<br /><searchLink fieldCode="AU" term="%22Jalota+D%22">Jalota D</searchLink>; PMV Pharmaceuticals, Princeton, NJ.<br /><searchLink fieldCode="AU" term="%22Fellous+M%22">Fellous M</searchLink>; PMV Pharmaceuticals, Princeton, NJ.<br /><searchLink fieldCode="AU" term="%22Schram+AM%22">Schram AM</searchLink>; Memorial Sloan Kettering Cancer Center, New York.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%220255562%22">The New England journal of medicine</searchLink> [N Engl J Med] 2026 Feb 26; Vol. 394 (9), pp. 872-883.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Clinical Trial, Phase I; Multicenter Study
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Massachusetts+Medical+Society%22">Massachusetts Medical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0255562 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1533-4406 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200284793%22">00284793 </searchLink><i>NLM ISO Abbreviation: </i>N Engl J Med <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41740031
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1056/NEJMoa2508820
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 872
    Titles:
      – TitleFull: Phase 1 Study of Rezatapopt, a p53 Reactivator, in TP53 Y220C-Mutated Tumors.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Dumbrava EE
      – PersonEntity:
          Name:
            NameFull: Shapiro GI
      – PersonEntity:
          Name:
            NameFull: Parikh AR
      – PersonEntity:
          Name:
            NameFull: Johnson ML
      – PersonEntity:
          Name:
            NameFull: Tolcher AW
      – PersonEntity:
          Name:
            NameFull: Thompson JA
      – PersonEntity:
          Name:
            NameFull: El-Khoueiry AB
      – PersonEntity:
          Name:
            NameFull: Vandross AL
      – PersonEntity:
          Name:
            NameFull: Kummar S
      – PersonEntity:
          Name:
            NameFull: Shepard DR
      – PersonEntity:
          Name:
            NameFull: LeDuke K
      – PersonEntity:
          Name:
            NameFull: Sheehan L
      – PersonEntity:
          Name:
            NameFull: Alland L
      – PersonEntity:
          Name:
            NameFull: Haque A
      – PersonEntity:
          Name:
            NameFull: Jalota D
      – PersonEntity:
          Name:
            NameFull: Fellous M
      – PersonEntity:
          Name:
            NameFull: Schram AM
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 26
              M: 02
              Text: 2026 Feb 26
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1533-4406
          Numbering:
            – Type: volume
              Value: 394
            – Type: issue
              Value: 9
          Titles:
            – TitleFull: The New England journal of medicine
              Type: main
ResultId 1