Association of duration of amino acids infusion and renal protection: a secondary analysis of the PROTECTION trial.
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| Title: | Association of duration of amino acids infusion and renal protection: a secondary analysis of the PROTECTION trial. |
|---|---|
| Authors: | Landoni G; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy; School of Medicine, Vita-Salute San Raffaele University, Milan, Italy. Electronic address: landoni.giovanni@hsr.it., Oriani A; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy., Ti LK; Department of Anaesthesia, National University Hospital, Singapore., Losiggio R; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy., Bradic N; Clinic for Anaesthesiology, Resuscitation and Intensive Medicine, University Hospital Dubrava, Zagreb, Croatia; Department of Nursing, University North, Varazdin, Croatia., Pruna A; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy., Burrell A; Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia; Department of Intensive Care and Hyperbaric Medicine, The Alfred, Melbourne, Australia., Pieri M; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy; School of Medicine, Vita-Salute San Raffaele University, Milan, Italy., Hodgson CL; Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia; Intensive Care Unit and Physiotherapy Department, The Alfred Hospital, Melbourne, Australia; Department of Critical Care, University of Melbourne, Melbourne, Australia., D'Amico F; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy., Ranucci M; Department of Cardiovascular Anaesthesia and Intensive Care, IRCCS Policlinico San Donato, San Donato Milanese, Italy., Oliva FM; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy., Comis M; S.C. Anestesia e Rianimazione Cardiovascolare, A.O. Ordine Mauriziano Umberto I di Torino, Turin, Italy., Calabrò MG; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy., Viscido C; S.C. Anestesia e Rianimazione Cardiovascolare, A.O. Ordine Mauriziano Umberto I di Torino, Turin, Italy., Ajello S; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy., Ferrod F; S.C. Anestesia e Rianimazione Cardiovascolare, A.O. Ordine Mauriziano Umberto I di Torino, Turin, Italy., Fresilli S; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy., Guarracino F; Department of Cardiothoracic and Vascular Anaesthesia and Intensive Care, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy., Damiani D; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy., Pisano A; Cardiac Anesthesia and Intensive Care Unit, AORN 'Dei Colli', Monaldi Hospital, Naples, Italy., Bonizzoni MA; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy., Silvetti S; Department of Cardiac Anaesthesia and Intensive Care, Ospedale Policlinico San Martino IRCCS-IRCCS Cardiovascular Network, Genoa, Italy., Pontillo D; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy., Neri G; Anesthesia and Intensive Care, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy., Scquizzato T; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy., Bosco V; Anesthesia and Intensive Care, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy., Marmiere M; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy., Carmosino M; Department of Health Sciences, School of Medicine, University of Basilicata, Potenza, Italy., Labanca R; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy., Federici F; Anestesia e Rianimazione, Azienda Ospedaliero-Universitaria Sant'Andrea, Rome, Italy., Giardina G; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy., Baiardo Redaelli M; Department of Biotechnologies and Life Sciences, University of Insubria, Varese, Italy; General and Neurosurgical Intensive Care Units, Ospedale di Circolo e Fondazione Macchi, ASST Sette Laghi, Varese, Italy., Belletti A; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy., Costamagna A; Department of Anaesthesia, Intensive Care and Emergency, 'Citta della Salute e della Scienza' University Hospital, Turin, Italy., Fominskiy E; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy., Arangino C; Department of Cardiothoracic Anaesthesia and Intensive Care, IRCCS Centro Cardiologico Monzino, Milan, Italy., Scandroglio AM; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy., Monti G; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy; School of Medicine, Vita-Salute San Raffaele University, Milan, Italy., Cortegiani A; Department of Precision Medicine in Medical, Surgical and Critical Care Area (Me.Pre.C.C.), University of Palermo, Palermo, Italy; General Intensive Care Unit, University Hospital Policlinico 'Paolo Giaccone', Palermo, Italy., Paternoster G; Department of Health Sciences, School of Medicine, University of Basilicata, Potenza, Italy; Department of Health Sciences, School of Medicine, University of Basilicata, Anaesthesia and ICU, San Carlo Hospital, Potenza, Italy., Bove T; Department of Basic Biotechnological Sciences, Intensive Care Peri-Operative Clinics, Università Cattolica del Sacro Cuore, Rome, Italy; Department of Emergency, Anaesthesiology and Reanimetion Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy., Bellomo R; Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia; Department of Critical Care, University of Melbourne, Melbourne, Australia., Zangrillo A; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy; School of Medicine, Vita-Salute San Raffaele University, Milan, Italy., Monaco F; Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum - University of Bologna, Bologna, Italy; Cardiothoracic and Vascular Anaesthesia and Intensive Care, IRCCS Azienda Ospedaliero-Universitaria Sant'Orsola, Bologna, Italy. |
| Corporate Authors: | PROTECTION Study Group Collaborators |
| Source: | British journal of anaesthesia [Br J Anaesth] 2026 Jul; Vol. 137 (1), pp. 110-117. Date of Electronic Publication: 2026 Feb 24. |
| Publication Type: | Journal Article; Randomized Controlled Trial |
| Journal Info: | Publisher: Elsevier Country of Publication: England NLM ID: 0372541 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-6771 (Electronic) Linking ISSN: 00070912 NLM ISO Abbreviation: Br J Anaesth Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41741282 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Association of duration of amino acids infusion and renal protection: a secondary analysis of the PROTECTION trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Landoni+G%22">Landoni G</searchLink>; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy; School of Medicine, Vita-Salute San Raffaele University, Milan, Italy. Electronic address: landoni.giovanni@hsr.it.<br /><searchLink fieldCode="AU" term="%22Oriani+A%22">Oriani A</searchLink>; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ti+LK%22">Ti LK</searchLink>; Department of Anaesthesia, National University Hospital, Singapore.<br /><searchLink fieldCode="AU" term="%22Losiggio+R%22">Losiggio R</searchLink>; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bradic+N%22">Bradic N</searchLink>; Clinic for Anaesthesiology, Resuscitation and Intensive Medicine, University Hospital Dubrava, Zagreb, Croatia; Department of Nursing, University North, Varazdin, Croatia.<br /><searchLink fieldCode="AU" term="%22Pruna+A%22">Pruna A</searchLink>; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Burrell+A%22">Burrell A</searchLink>; Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia; Department of Intensive Care and Hyperbaric Medicine, The Alfred, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Pieri+M%22">Pieri M</searchLink>; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy; School of Medicine, Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Hodgson+CL%22">Hodgson CL</searchLink>; Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia; Intensive Care Unit and Physiotherapy Department, The Alfred Hospital, Melbourne, Australia; Department of Critical Care, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22D'Amico+F%22">D'Amico F</searchLink>; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ranucci+M%22">Ranucci M</searchLink>; Department of Cardiovascular Anaesthesia and Intensive Care, IRCCS Policlinico San Donato, San Donato Milanese, Italy.<br /><searchLink fieldCode="AU" term="%22Oliva+FM%22">Oliva FM</searchLink>; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Comis+M%22">Comis M</searchLink>; S.C. Anestesia e Rianimazione Cardiovascolare, A.O. Ordine Mauriziano Umberto I di Torino, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Calabrò+MG%22">Calabrò MG</searchLink>; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Viscido+C%22">Viscido C</searchLink>; S.C. Anestesia e Rianimazione Cardiovascolare, A.O. Ordine Mauriziano Umberto I di Torino, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Ajello+S%22">Ajello S</searchLink>; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ferrod+F%22">Ferrod F</searchLink>; S.C. Anestesia e Rianimazione Cardiovascolare, A.O. Ordine Mauriziano Umberto I di Torino, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Fresilli+S%22">Fresilli S</searchLink>; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Guarracino+F%22">Guarracino F</searchLink>; Department of Cardiothoracic and Vascular Anaesthesia and Intensive Care, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Damiani+D%22">Damiani D</searchLink>; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pisano+A%22">Pisano A</searchLink>; Cardiac Anesthesia and Intensive Care Unit, AORN 'Dei Colli', Monaldi Hospital, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Bonizzoni+MA%22">Bonizzoni MA</searchLink>; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Silvetti+S%22">Silvetti S</searchLink>; Department of Cardiac Anaesthesia and Intensive Care, Ospedale Policlinico San Martino IRCCS-IRCCS Cardiovascular Network, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Pontillo+D%22">Pontillo D</searchLink>; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Neri+G%22">Neri G</searchLink>; Anesthesia and Intensive Care, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Scquizzato+T%22">Scquizzato T</searchLink>; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bosco+V%22">Bosco V</searchLink>; Anesthesia and Intensive Care, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Marmiere+M%22">Marmiere M</searchLink>; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Carmosino+M%22">Carmosino M</searchLink>; Department of Health Sciences, School of Medicine, University of Basilicata, Potenza, Italy.<br /><searchLink fieldCode="AU" term="%22Labanca+R%22">Labanca R</searchLink>; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Federici+F%22">Federici F</searchLink>; Anestesia e Rianimazione, Azienda Ospedaliero-Universitaria Sant'Andrea, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Giardina+G%22">Giardina G</searchLink>; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Baiardo+Redaelli+M%22">Baiardo Redaelli M</searchLink>; Department of Biotechnologies and Life Sciences, University of Insubria, Varese, Italy; General and Neurosurgical Intensive Care Units, Ospedale di Circolo e Fondazione Macchi, ASST Sette Laghi, Varese, Italy.<br /><searchLink fieldCode="AU" term="%22Belletti+A%22">Belletti A</searchLink>; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Costamagna+A%22">Costamagna A</searchLink>; Department of Anaesthesia, Intensive Care and Emergency, 'Citta della Salute e della Scienza' University Hospital, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Fominskiy+E%22">Fominskiy E</searchLink>; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Arangino+C%22">Arangino C</searchLink>; Department of Cardiothoracic Anaesthesia and Intensive Care, IRCCS Centro Cardiologico Monzino, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Scandroglio+AM%22">Scandroglio AM</searchLink>; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Monti+G%22">Monti G</searchLink>; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy; School of Medicine, Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cortegiani+A%22">Cortegiani A</searchLink>; Department of Precision Medicine in Medical, Surgical and Critical Care Area (Me.Pre.C.C.), University of Palermo, Palermo, Italy; General Intensive Care Unit, University Hospital Policlinico 'Paolo Giaccone', Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Paternoster+G%22">Paternoster G</searchLink>; Department of Health Sciences, School of Medicine, University of Basilicata, Potenza, Italy; Department of Health Sciences, School of Medicine, University of Basilicata, Anaesthesia and ICU, San Carlo Hospital, Potenza, Italy.<br /><searchLink fieldCode="AU" term="%22Bove+T%22">Bove T</searchLink>; Department of Basic Biotechnological Sciences, Intensive Care Peri-Operative Clinics, Università Cattolica del Sacro Cuore, Rome, Italy; Department of Emergency, Anaesthesiology and Reanimetion Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Bellomo+R%22">Bellomo R</searchLink>; Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia; Department of Critical Care, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Zangrillo+A%22">Zangrillo A</searchLink>; Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy; School of Medicine, Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Monaco+F%22">Monaco F</searchLink>; Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum - University of Bologna, Bologna, Italy; Cardiothoracic and Vascular Anaesthesia and Intensive Care, IRCCS Azienda Ospedaliero-Universitaria Sant'Orsola, Bologna, Italy. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22PROTECTION+Study+Group+Collaborators%22">PROTECTION Study Group Collaborators</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220372541%22">British journal of anaesthesia</searchLink> [Br J Anaesth] 2026 Jul; Vol. 137 (1), pp. 110-117. <i>Date of Electronic Publication: </i>2026 Feb 24. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Randomized Controlled Trial – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0372541 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1471-6771 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200070912%22">00070912 </searchLink><i>NLM ISO Abbreviation: </i>Br J Anaesth <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.bja.2025.12.054 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 110 Titles: – TitleFull: Association of duration of amino acids infusion and renal protection: a secondary analysis of the PROTECTION trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Landoni G – PersonEntity: Name: NameFull: Oriani A – PersonEntity: Name: NameFull: Ti LK – PersonEntity: Name: NameFull: Losiggio R – PersonEntity: Name: NameFull: Bradic N – PersonEntity: Name: NameFull: Pruna A – PersonEntity: Name: NameFull: Burrell A – PersonEntity: Name: NameFull: Pieri M – PersonEntity: Name: NameFull: Hodgson CL – PersonEntity: Name: NameFull: D'Amico F – PersonEntity: Name: NameFull: Ranucci M – PersonEntity: Name: NameFull: Oliva FM – PersonEntity: Name: NameFull: Comis M – PersonEntity: Name: NameFull: Calabrò MG – PersonEntity: Name: NameFull: Viscido C – PersonEntity: Name: NameFull: Ajello S – PersonEntity: Name: NameFull: Ferrod F – PersonEntity: Name: NameFull: Fresilli S – PersonEntity: Name: NameFull: Guarracino F – PersonEntity: Name: NameFull: Damiani D – PersonEntity: Name: NameFull: Pisano A – PersonEntity: Name: NameFull: Bonizzoni MA – PersonEntity: Name: NameFull: Silvetti S – PersonEntity: Name: NameFull: Pontillo D – PersonEntity: Name: NameFull: Neri G – PersonEntity: Name: NameFull: Scquizzato T – PersonEntity: Name: NameFull: Bosco V – PersonEntity: Name: NameFull: Marmiere M – PersonEntity: Name: NameFull: Carmosino M – PersonEntity: Name: NameFull: Labanca R – PersonEntity: Name: NameFull: Federici F – PersonEntity: Name: NameFull: Giardina G – PersonEntity: Name: NameFull: Baiardo Redaelli M – PersonEntity: Name: NameFull: Belletti A – PersonEntity: Name: NameFull: Costamagna A – PersonEntity: Name: NameFull: Fominskiy E – PersonEntity: Name: NameFull: Arangino C – PersonEntity: Name: NameFull: Scandroglio AM – PersonEntity: Name: NameFull: Monti G – PersonEntity: Name: NameFull: Cortegiani A – PersonEntity: Name: NameFull: Paternoster G – PersonEntity: Name: NameFull: Bove T – PersonEntity: Name: NameFull: Bellomo R – PersonEntity: Name: NameFull: Zangrillo A – PersonEntity: Name: NameFull: Monaco F IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: 2026 Jul Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1471-6771 Numbering: – Type: volume Value: 137 – Type: issue Value: 1 Titles: – TitleFull: British journal of anaesthesia Type: main |
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