Biomarker for craving and acamprosate treatment response in patients with alcohol use disorder: insights from multi-omics.

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Title: Biomarker for craving and acamprosate treatment response in patients with alcohol use disorder: insights from multi-omics.
Authors: Ho MF; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA. ho.mingfen@mayo.edu.; Department of Molecular Pharmacology and Experimental Therapeutics; Mayo Clinic, Rochester, MN, USA. ho.mingfen@mayo.edu., Zhang C; Department of Molecular Pharmacology and Experimental Therapeutics; Mayo Clinic, Rochester, MN, USA., Coombes BJ; Division of Computational Biology, Quantitative Health Sciences; Mayo Clinic, Rochester, MN, USA., Biernacka JM; Division of Computational Biology, Quantitative Health Sciences; Mayo Clinic, Rochester, MN, USA., Croarkin PE; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA., Oesterle TS; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA., Karpyak VM; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA., Li H; Department of Molecular Pharmacology and Experimental Therapeutics; Mayo Clinic, Rochester, MN, USA., Weinshilboum RM; Department of Molecular Pharmacology and Experimental Therapeutics; Mayo Clinic, Rochester, MN, USA.
Source: Molecular psychiatry [Mol Psychiatry] 2026 Jul; Vol. 31 (7), pp. 3746-3757. Date of Electronic Publication: 2026 Feb 25.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Ho+MF%22">Ho MF</searchLink>; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA. ho.mingfen@mayo.edu.; Department of Molecular Pharmacology and Experimental Therapeutics; Mayo Clinic, Rochester, MN, USA. ho.mingfen@mayo.edu.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Department of Molecular Pharmacology and Experimental Therapeutics; Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Coombes+BJ%22">Coombes BJ</searchLink>; Division of Computational Biology, Quantitative Health Sciences; Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Biernacka+JM%22">Biernacka JM</searchLink>; Division of Computational Biology, Quantitative Health Sciences; Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Croarkin+PE%22">Croarkin PE</searchLink>; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Oesterle+TS%22">Oesterle TS</searchLink>; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Karpyak+VM%22">Karpyak VM</searchLink>; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Department of Molecular Pharmacology and Experimental Therapeutics; Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Weinshilboum+RM%22">Weinshilboum RM</searchLink>; Department of Molecular Pharmacology and Experimental Therapeutics; Mayo Clinic, Rochester, MN, USA.
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        Value: 10.1038/s41380-026-03506-6
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        Text: English
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              Text: 2026 Jul
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              Y: 2026
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