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Apixaban Versus Aspirin and Risk of Hemorrhage in the ARCADIA Trial.

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Title: Apixaban Versus Aspirin and Risk of Hemorrhage in the ARCADIA Trial.
Authors: Kamel H; Clinical and Translational Neuroscience Unit, Department of Neurology and Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY., Longstreth WT Jr; Department of Neurology, University of Washington, Seattle, WA.; Department of Medicine, University of Washington, Seattle, WA.; Department of Epidemiology, University of Washington, Seattle, WA., Tirschwell DL; Department of Neurology, University of Washington, Seattle, WA., Kronmal RA; Department of Biostatistics, University of Washington, Seattle, WA., Elkind MSV; Department of Neurology, Vagelos College of Physicians and Surgeons, New York, NY.; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY., Pauls Q; Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC., Garcia RA; Department of Neurology, Vagelos College of Physicians and Surgeons, New York, NY., Plummer P; Department of Neurology and Rehabilitation Medicine, University of Cincinnati College of Medicine, Cincinnati, OH., Sabagha N; Department of Neurology and Rehabilitation Medicine, University of Cincinnati College of Medicine, Cincinnati, OH., Ammar A; Clinical and Translational Neuroscience Unit, Department of Neurology and Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY., Healey JS; Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada., Shoamanesh A; Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada., Sheth KN; Department of Neurology, Yale School of Medicine, New Haven, CT., Broderick JP; Department of Neurology and Rehabilitation Medicine, University of Cincinnati College of Medicine, Cincinnati, OH., Navi BB; Clinical and Translational Neuroscience Unit, Department of Neurology and Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.
Corporate Authors: ARCADIA Investigators
Source: Annals of neurology [Ann Neurol] 2026 Jun; Vol. 99 (6), pp. 1589-1597. Date of Electronic Publication: 2026 Feb 25.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Comparative Study
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7707449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-8249 (Electronic) Linking ISSN: 03645134 NLM ISO Abbreviation: Ann Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Apixaban Versus Aspirin and Risk of Hemorrhage in the ARCADIA Trial.
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  Data: <searchLink fieldCode="AU" term="%22Kamel+H%22">Kamel H</searchLink>; Clinical and Translational Neuroscience Unit, Department of Neurology and Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.<br /><searchLink fieldCode="AU" term="%22Longstreth+WT+Jr%22">Longstreth WT Jr</searchLink>; Department of Neurology, University of Washington, Seattle, WA.; Department of Medicine, University of Washington, Seattle, WA.; Department of Epidemiology, University of Washington, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Tirschwell+DL%22">Tirschwell DL</searchLink>; Department of Neurology, University of Washington, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Kronmal+RA%22">Kronmal RA</searchLink>; Department of Biostatistics, University of Washington, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Elkind+MSV%22">Elkind MSV</searchLink>; Department of Neurology, Vagelos College of Physicians and Surgeons, New York, NY.; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY.<br /><searchLink fieldCode="AU" term="%22Pauls+Q%22">Pauls Q</searchLink>; Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC.<br /><searchLink fieldCode="AU" term="%22Garcia+RA%22">Garcia RA</searchLink>; Department of Neurology, Vagelos College of Physicians and Surgeons, New York, NY.<br /><searchLink fieldCode="AU" term="%22Plummer+P%22">Plummer P</searchLink>; Department of Neurology and Rehabilitation Medicine, University of Cincinnati College of Medicine, Cincinnati, OH.<br /><searchLink fieldCode="AU" term="%22Sabagha+N%22">Sabagha N</searchLink>; Department of Neurology and Rehabilitation Medicine, University of Cincinnati College of Medicine, Cincinnati, OH.<br /><searchLink fieldCode="AU" term="%22Ammar+A%22">Ammar A</searchLink>; Clinical and Translational Neuroscience Unit, Department of Neurology and Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.<br /><searchLink fieldCode="AU" term="%22Healey+JS%22">Healey JS</searchLink>; Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Shoamanesh+A%22">Shoamanesh A</searchLink>; Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Sheth+KN%22">Sheth KN</searchLink>; Department of Neurology, Yale School of Medicine, New Haven, CT.<br /><searchLink fieldCode="AU" term="%22Broderick+JP%22">Broderick JP</searchLink>; Department of Neurology and Rehabilitation Medicine, University of Cincinnati College of Medicine, Cincinnati, OH.<br /><searchLink fieldCode="AU" term="%22Navi+BB%22">Navi BB</searchLink>; Clinical and Translational Neuroscience Unit, Department of Neurology and Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY.
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              Text: 2026 Jun
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