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Investigating the mechanisms by which bisphenol A affects osteoarthritis through a novel network toxicology framework and experimental validation.

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Title: Investigating the mechanisms by which bisphenol A affects osteoarthritis through a novel network toxicology framework and experimental validation.
Authors: He Q; Hubei University of Chinese Medicine, Wuhan, 430061, China.; Hubei Provincial Hospital of Traditional Chinese Medicine, Affiliated Hospital of Hubei University of Chinese Medicine, Hubei Key Laboratory of Theory and Application Research of Liver and Kidney in Traditional Chinese Medicine, Hubei Province Academy of Traditional Chinese Medicine, Wuhan, 430061, China.; Hubei Shizhen Laboratory, Wuhan, 430061, China., Li S; Key Laboratory of Clinical Cohort Research on Bone and Joint Degenerative Diseases of Guangxi, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, 533000, China., Chen Y; Fujian University of Traditional Chinese Medicine, Fuzhou, 350108, China., Liu Y; General Hospital of Western Theater Command, Chengdu, 610083, China., Li Y; Hubei University of Chinese Medicine, Wuhan, 430061, China.; Hubei Shizhen Laboratory, Wuhan, 430061, China., Min S; Changzhou Hospital of Traditional Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Changzhou, 213000, China., Yi S; Hubei University of Chinese Medicine, Wuhan, 430061, China.; Hubei Shizhen Laboratory, Wuhan, 430061, China., Li F; Hubei University of Chinese Medicine, Wuhan, 430061, China.; Hubei Shizhen Laboratory, Wuhan, 430061, China., Zhou X; Hubei University of Chinese Medicine, Wuhan, 430061, China. 1686090116@qq.com.; Hubei Shizhen Laboratory, Wuhan, 430061, China. 1686090116@qq.com.
Source: BMC pharmacology & toxicology [BMC Pharmacol Toxicol] 2026 Feb 25; Vol. 27 (1). Date of Electronic Publication: 2026 Feb 25.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101590449 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-6511 (Electronic) Linking ISSN: 20506511 NLM ISO Abbreviation: BMC Pharmacol Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Investigating the mechanisms by which bisphenol A affects osteoarthritis through a novel network toxicology framework and experimental validation.
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  Data: <searchLink fieldCode="AU" term="%22He+Q%22">He Q</searchLink>; Hubei University of Chinese Medicine, Wuhan, 430061, China.; Hubei Provincial Hospital of Traditional Chinese Medicine, Affiliated Hospital of Hubei University of Chinese Medicine, Hubei Key Laboratory of Theory and Application Research of Liver and Kidney in Traditional Chinese Medicine, Hubei Province Academy of Traditional Chinese Medicine, Wuhan, 430061, China.; Hubei Shizhen Laboratory, Wuhan, 430061, China.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; Key Laboratory of Clinical Cohort Research on Bone and Joint Degenerative Diseases of Guangxi, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, 533000, China.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Fujian University of Traditional Chinese Medicine, Fuzhou, 350108, China.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; General Hospital of Western Theater Command, Chengdu, 610083, China.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Hubei University of Chinese Medicine, Wuhan, 430061, China.; Hubei Shizhen Laboratory, Wuhan, 430061, China.<br /><searchLink fieldCode="AU" term="%22Min+S%22">Min S</searchLink>; Changzhou Hospital of Traditional Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Changzhou, 213000, China.<br /><searchLink fieldCode="AU" term="%22Yi+S%22">Yi S</searchLink>; Hubei University of Chinese Medicine, Wuhan, 430061, China.; Hubei Shizhen Laboratory, Wuhan, 430061, China.<br /><searchLink fieldCode="AU" term="%22Li+F%22">Li F</searchLink>; Hubei University of Chinese Medicine, Wuhan, 430061, China.; Hubei Shizhen Laboratory, Wuhan, 430061, China.<br /><searchLink fieldCode="AU" term="%22Zhou+X%22">Zhou X</searchLink>; Hubei University of Chinese Medicine, Wuhan, 430061, China. 1686090116@qq.com.; Hubei Shizhen Laboratory, Wuhan, 430061, China. 1686090116@qq.com.
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  Data: <searchLink fieldCode="JN" term="%22101590449%22">BMC pharmacology & toxicology</searchLink> [BMC Pharmacol Toxicol] 2026 Feb 25; Vol. 27 (1). <i>Date of Electronic Publication: </i>2026 Feb 25.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101590449 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2050-6511 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220506511%22">20506511 </searchLink><i>NLM ISO Abbreviation: </i>BMC Pharmacol Toxicol <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41742320
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        Value: 10.1186/s40360-026-01108-0
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        Text: English
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              Text: 2026 Feb 25
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              Y: 2026
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